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Forensic Toxicology

, Volume 26, Issue 1, pp 6–12 | Cite as

Simultaneous analysis of six phenethylamine-type designer drugs by TLC, LC-MS, and GC-MS

  • Kohei Kanai
  • Kenichi Takekawa
  • Takuya Kumamoto
  • Tsutomu Ishikawa
  • Takeshi OhmoriEmail author
Original Article

Abstract

Extensive data are presented for simultaneous analysis of six phenethylamine-type designer drugs. The drugs are 2,5-dimethoxyphenethylamine (2C-H), 2,5-dimethoxyamphetamine (2,5-DMA), 4-bromo-2,5-dimethoxyphenethylamine (2C-B), 4-bromo-2,5-dimethoxyamphetamine (DOB), 4-iodo-2,5-dimethoxyphenethylamine (2C-I), and 4-iodo-2,5-dimethoxyamphetamine (DOI). The data include their proton nuclear magnetic resonance (NMR) spectra, infrared spectra, retention times detected by liquid chromatography (LC) and gas chromatography (GC), thin-layer chromatography (TLC) data using seven solvent mixture systems, electrospray ionization (ESI) mass spectra without derivatization, and electron ionization (EI) mass spectra with trifl uoroacetyl (TFA) derivatization. Quantitative reliability was also tested for these compounds by LC-mass spectrometry (MS) and GC-MS in high concentration ranges. The data concerned is intended to serve for screening, identification, and quantitation of the drugs contained in seized tablets, crystals, and powder; the data are very useful for such purposes in actual forensic toxicological practice.

Keywords

2,5-Dimethoxyphenethylamine analogues Designer drugs 2C-B DOB 2C-I DOI 

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Copyright information

© Japanese Association of Forensic Toxicology 2008

Authors and Affiliations

  • Kohei Kanai
    • 1
  • Kenichi Takekawa
    • 1
  • Takuya Kumamoto
    • 2
  • Tsutomu Ishikawa
    • 2
  • Takeshi Ohmori
    • 3
    Email author
  1. 1.Forensic Science LaboratoryYamanashi Prefectural Police H.Q.YamanashiJapan
  2. 2.Graduate School of Pharmaceutical ScienceChiba UniversityChibaJapan
  3. 3.National Research Institute of Police ScienceKashiwa, ChibaJapan

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