Journal of Natural Medicines

, Volume 72, Issue 2, pp 576–581 | Cite as

Rigenolides D–H, norsecoiridoid and secoiridoids from Gentiana rigescens Franch

  • Yoshihiro Suyama
  • Naonobu Tanaka
  • Kazuyoshi Kawazoe
  • Kotaro Murakami
  • Shun-Lin Li
  • Han-Dong Sun
  • Yoshiki KashiwadaEmail author


Five new compounds, rigenolides D–H (15), were isolated from the aerial parts of Gentiana rigescens Franch. Their structures were assigned by detailed spectroscopic analyses and chemical conversions. Rigenolides D (1) and E (2) were elucidated to be a secoiridoid and a norsecoiridoid, respectively, possessing a dienone moiety in common. Rigenolides F–H (35) were assigned as acylated secoiridoid glucosides.


Norsecoiridoid Secoiridoid Secoiridoid glucoside Gentiana rigescens Rigenolides D–H 



This work was partly supported by JSPS KAKENHI Grant numbers JP18406028 and JP17K08337.


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Copyright information

© The Japanese Society of Pharmacognosy and Springer Japan KK, part of Springer Nature 2018

Authors and Affiliations

  • Yoshihiro Suyama
    • 1
  • Naonobu Tanaka
    • 1
    • 2
  • Kazuyoshi Kawazoe
    • 3
  • Kotaro Murakami
    • 4
  • Shun-Lin Li
    • 5
  • Han-Dong Sun
    • 5
  • Yoshiki Kashiwada
    • 1
    Email author
  1. 1.Graduate School of Pharmaceutical SciencesTokushima UniversityTokushimaJapan
  2. 2.Graduate School of Technology, Industrial and Social SciencesTokushima UniversityTokushimaJapan
  3. 3.School of PharmacyShowa UniversityShinagawaJapan
  4. 4.Faculty of Pharmaceutical SciencesSojo UniversityKumamotoJapan
  5. 5.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kumming Institute of BotanyChinese Academy of SciencesKummingChina

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