The active glycosides from Urtica fissa rhizome decoction
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Using bioassay guided fractionation, 16 glycosides, including two new compounds (1 and 2), were isolated from the anticomplement and anti-inflammatory portion of an Urtica fissa rhizome decoction used for arthritis. Several compounds were found to possess significant anticomplement and anti-inflammatory activities. This study revealed that glycosides played an important role in the therapeutic effects of Urtica fissa rhizome.
KeywordsUrtica fissa Decoction Glycoside Anticomplement Anti-inflammatory
This study was financially supported by a grant of the National Natural Science Fund of China (No. 81374067). The authors would like to thank Dr. Bona Dai of the Instrumental Analysis Center of Shanghai Jiao Tong University for NMR measurement.
Compliance with ethical standards
Conflict of interest
The authors declare that there is no any conflict of interest to disclose.
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