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Phenylethanoid and flavone glycosides from Ruellia tuberosa L.

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Abstract

A new phenylethanoid glycoside, isocassifolioside (8), and two new flavone glycosides, hispidulin 7-O-α-l-rhamnopyranosyl-(1′″ → 2″)-O-β-d-glucuronopyranoside (11) and pectolinaringenin 7-O-α-l-rhamnopyranosyl-(1′″ → 2″)-O-β-d-glucuronopyranoside (12) were isolated from the aerial portions of Ruellia tuberosa L., together with verbascoside (1), isoverbascoside (2), nuomioside (3), isonuomioside (4), forsythoside B (5), paucifloside (6), cassifolioside (7), hispidulin 7-O-β-d-glucuronopyranoside (9) and comanthoside B (10). The structure elucidations were based on analyses of chemical and spectroscopic data including 1D- and 2D-NMR. The isolated compounds 1–12 exhibited radical scavenging activity using ORAC assay.

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Acknowledgments

This study was financially supported by The Thailand Research Fund (Grant No. DBG5480007) and Chulabhorn Research Institute. Also, C.P. would like to thank Thailand International Development Cooperation Agency (TICA) for providing financial support during study in Thailand.

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Authors and Affiliations

  1. Chemial Biology Program, Chulabhorn Graduate Institute, Kamphaeng Phet 6, Bangkok, 10210, Thailand

    Chiobouaphong Phakeovilay, Wannaporn Disadee, Poolsak Sahakitpichan, Prasat Kittakoop & Somsak Ruchirawat

  2. Chulabhorn Research Institute, Kamphaeng Phet 6, Bangkok, 10210, Thailand

    Wannaporn Disadee, Poolsak Sahakitpichan, Somkit Sitthimonchai, Prasat Kittakoop, Somsak Ruchirawat & Tripetch Kanchanapoom

  3. Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, 40002, Thailand

    Tripetch Kanchanapoom

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  1. Chiobouaphong Phakeovilay
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  2. Wannaporn Disadee
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  7. Tripetch Kanchanapoom
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Correspondence to Tripetch Kanchanapoom.

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Phakeovilay, C., Disadee, W., Sahakitpichan, P. et al. Phenylethanoid and flavone glycosides from Ruellia tuberosa L.. J Nat Med 67, 228–233 (2013). https://doi.org/10.1007/s11418-012-0658-7

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  • DOI: https://doi.org/10.1007/s11418-012-0658-7

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