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Journal of Natural Medicines

, Volume 64, Issue 3, pp 354–357 | Cite as

A pterocarpan from the seeds of Bituminaria morisiana

  • Marco Leonti
  • Laura Casu
  • Jürg Gertsch
  • Leonardo Bonsignore
  • Costantino Floris
  • Mariano Casu
  • Filippo Cottiglia
Note

Abstract

A new prenylated pterocarpan, named morisianine, was isolated together with the known secondary metabolites erybraedin C, psoralen and angelicin from the seeds of Bituminaria morisiana. The structures of the compounds were elucidated mainly by 1D and 2D NMR experiments as well as mass spectrometry. The new compound was subjected to cytotoxicity screening against a panel of human cancer cells.

Keywords

Bituminaria morisiana Psoralea Fabaceae Pterocarpans Cytotoxicity 

Notes

Acknowledgments

The authors thank Prof. Bruno De Martis of Dipartimento di Scienze Botaniche, University of Cagliari, for identification of plant material. We would also like to thank Dr. Pierluigi Caboni for high-resolution mass spectrum measurement. This work was supported by grants from Fondazione Banco di Sardegna.

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Copyright information

© The Japanese Society of Pharmacognosy and Springer 2010

Authors and Affiliations

  • Marco Leonti
    • 1
  • Laura Casu
    • 1
  • Jürg Gertsch
    • 3
  • Leonardo Bonsignore
    • 1
  • Costantino Floris
    • 2
  • Mariano Casu
    • 2
  • Filippo Cottiglia
    • 1
  1. 1.Dipartimento Farmaco Chimico TecnologicoUniversity of CagliariCagliariItaly
  2. 2.Dipartimento di Scienze ChimicheUniversity of Cagliari, Complesso di MonserratoMonserratoItaly
  3. 3.Institute of Biochemistry and Molecular MedicineUniversity of BernBernSwitzerland

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