Journal of Natural Medicines

, Volume 63, Issue 1, pp 102–104 | Cite as

Sesquiterpenes from Curcuma comosa

  • Yang Qu
  • Fengming Xu
  • Seikou Nakamura
  • Hisashi Matsuda
  • Yutana Pongpiriyadacha
  • Lijun Wu
  • Masayuki YoshikawaEmail author
Natural Medicine Note


From the dried rhizomes of Curcuma comosa cultivating in Thailand, 26 known sesquiterpenes were isolated: zederone, zederone epoxide, furanodienone, isofuranodienone, 1(10)Z,4Z-furanodiene-6-one, glechomanolide, dehydrocurdione, neocurdione, curdione, 7α-hydroxyneocurdione, 7β-hydroxycurdione, germacrone-1(10),4-diepoxide, germacrone, 13-hydroxygermacrone, curzerenone, curcolonol, alismol, alismoxide, zedoarondiol, isozedoarondiol, procurcumenol, isoprocurcumenol, aerugidiol, zedoalactone B, curcumenone, and curcumadione. Their structures were elucidated on the basis of physicochemical evidence. Among them, glechomanolide, curzerenone, curcolonol, alismol, alismoxide, and zedoarondiol showed no significant optical activities, so they may be artifact products during the isolation or drying process.


Curcuma comosa Zingiberaceae Sesquiterpenes 



This research was supported by the 21st COE Program, Academic Frontier Project, and a Grant-in-Aid for Scientific Research from MEXT (the Ministry of Education, Culture, Sports, Science and Technology of Japan).


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Copyright information

© The Japanese Society of Pharmacognosy and Springer 2008

Authors and Affiliations

  • Yang Qu
    • 1
  • Fengming Xu
    • 2
  • Seikou Nakamura
    • 2
  • Hisashi Matsuda
    • 2
  • Yutana Pongpiriyadacha
    • 3
  • Lijun Wu
    • 1
  • Masayuki Yoshikawa
    • 2
    Email author
  1. 1.School of Traditional Chinese Materia MedicaShenyang Pharmaceutical UniversityShenyangChina
  2. 2.Kyoto Pharmaceutical UniversityKyotoJapan
  3. 3.Rajamangala University of Technology SrivijayaNakhon Si ThammaratThailand

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