Journal of Natural Medicines

, Volume 62, Issue 2, pp 168–173 | Cite as

Cesdiurins I–III, steroidal saponins from Cestrum diurnum L.

  • Mostafa A. Fouad
  • Khaled M. Mohamed
  • Mohamed S. Kamel
  • Katsuyoshi Matsunami
  • Hideaki Otsuka
Original Paper


Phytochemical investigation of a methanolic extract of leaves of Cestrum diurnum L (Solanaceae) resulted in isolation of several furostanol steroidal saponins, named cesdiurins I–III (13). Their structures of the isolated compounds were determined by spectroscopic analyses, including by use of 1D and 2D NMR spectroscopic techniques as well as by mass spectral analyses.


Cestrum diurnum Solanaceae Furostanol Steroidal saponin 



The authors are grateful to The Japan Society of The Promotion of Science for the financial support of this work (M.S.K.), and the Research Center of Molecular Medicine of the Graduate School of Biomedical Sciences, Hiroshima University, for the NMR measurements. This work also was supported in part by Grant-in-Aid from the Ministry of Education, Science, Sports, Culture and Technology of Japan (No. 18590117 and 18032050). Thanks are also due to Astellas Foundation for Research on Medicinal Resources and Takeda Science Foundation for financial supports.


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Copyright information

© The Japanese Society of Pharmacognosy and Springer 2007

Authors and Affiliations

  • Mostafa A. Fouad
    • 1
  • Khaled M. Mohamed
    • 2
  • Mohamed S. Kamel
    • 1
  • Katsuyoshi Matsunami
    • 3
  • Hideaki Otsuka
    • 3
  1. 1.Department of Pharmacognosy, Faculty of PharmacyEl-Minia UniversityEl-MiniaEgypt
  2. 2.Department of Pharmacognosy, Faculty of PharmacyAssiut UniversityAssiutEgypt
  3. 3.Department of Pharmacognosy, Graduate School of Biomedical SciencesHiroshima UniversityMinami-kuJapan

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