Journal of Natural Medicines

, Volume 61, Issue 4, pp 480–482 | Cite as

Lignan glycosides and flavonoids from Saraca asoca with antioxidant activity

  • Samir Kumar Sadhu
  • Amina Khatun
  • Panadda Phattanawasin
  • Takashi Ohtsuki
  • Masami IshibashiEmail author
Natural Medicine Note


Five lignan glycosides, lyoniside, nudiposide, 5-methoxy-9-β-xylopyranosyl-(−)-isolariciresinol, icariside E3, and schizandriside, and three flavonoids, (−)-epicatechin, epiafzelechin-(4β→8)-epicatechin and procyanidin B2, together with β-sitosterol glucoside, were isolated from a methyl alcohol (MeOH) extract of Saraca asoca dried bark. Their structures were determined by 1D and 2D nuclear magnetic resonance (NMR) and mass spectroscopic analysis. Antioxidant activities were evaluated by 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging assay.


Saraca asoca Caesalpiniaceae Lignan glycoside Flavonoid Antioxidant activity 



This work was partly supported by a Grant-in-Aid from Tokyo Biochemical Research Foundation (TBRF), Japan.


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Copyright information

© The Japanese Society of Pharmacognosy and Springer 2007

Authors and Affiliations

  • Samir Kumar Sadhu
    • 1
    • 2
  • Amina Khatun
    • 2
  • Panadda Phattanawasin
    • 3
  • Takashi Ohtsuki
    • 1
  • Masami Ishibashi
    • 1
    Email author
  1. 1.Graduate School of Pharmaceutical SciencesChiba UniversityChibaJapan
  2. 2.Pharmacy Discipline, Life Science SchoolKhulna UniversityKhulnaBangladesh
  3. 3.Faculty of PharmacySilpakorn UniversityNakorn PathomThailand

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