Monoterpene glycoside and flavonoids from Blumea lacera
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The dichloromethane extract of air-dried leaves of Blumea lacera (Asteraceae) afforded α-pinene-7β-O-β-d-2,6-diacetylglucopyranoside (1), 5,4′-dihydroxy-6,7,3′-trimethoxyflavone (2), and 3,5,4′-trihydroxy-6,7,3′-trimethoxyflavone (3). Compounds 1–3 showed moderate activity against Candida albicans, low activity against Trichophyton mentagrophytes, and were inactive against Aspergillus niger. Compounds 1 and 3 indicated low activity against Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus and were inactive against Bacillus subtilis, while 2 was inactive against all four bacteria tested.
KeywordsBlumea lacera Asteraceae Monoterpene glycoside Flavonoids Antimicrobial
The antimicrobial tests were conducted at the University of the Philippines-Natural Sciences Research Institute (UP-NSRI). A research grant from the National Research Council of the Philippines is gratefully acknowledged.
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