Advertisement

Journal of Natural Medicines

, Volume 61, Issue 4, pp 474–475 | Cite as

Monoterpene glycoside and flavonoids from Blumea lacera

  • Consolacion Y. RagasaEmail author
  • Jeannie Wong
  • John A. Rideout
Natural Medicine Note

Abstract

The dichloromethane extract of air-dried leaves of Blumea lacera (Asteraceae) afforded α-pinene-7β-O-β-d-2,6-diacetylglucopyranoside (1), 5,4′-dihydroxy-6,7,3′-trimethoxyflavone (2), and 3,5,4′-trihydroxy-6,7,3′-trimethoxyflavone (3). Compounds 13 showed moderate activity against Candida albicans, low activity against Trichophyton mentagrophytes, and were inactive against Aspergillus niger. Compounds 1 and 3 indicated low activity against Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus and were inactive against Bacillus subtilis, while 2 was inactive against all four bacteria tested.

Keywords

Blumea lacera Asteraceae Monoterpene glycoside Flavonoids Antimicrobial 

Notes

Acknowledgments

The antimicrobial tests were conducted at the University of the Philippines-Natural Sciences Research Institute (UP-NSRI). A research grant from the National Research Council of the Philippines is gratefully acknowledged.

References

  1. 1.
    Quisumbing E (1998) Medicinal plants of the Philippines. Bureau of Printing, Manila, pp 966–967Google Scholar
  2. 2.
    Chiang LC, Cheng HY, Chen CC, Lin CC (2004) In vitro anti-leukemic and antiviral activities of traditionally used medicinal plants in Taiwan. Am J Chin Med 32:695–704PubMedCrossRefGoogle Scholar
  3. 3.
    Le VH, Tran TM, Nguyen XD (2003) Essential oils of Blumea lacera (Burm.F) DC. (Asteraceae) produced from aerial parts of plants grown in Central Vietnam. J Essential Oil-Bearing Plants 6:36–40Google Scholar
  4. 4.
    Laakso I, Seppanen-Laakso T, Hiltunen R, Ekundayo O (1989) Composition of the essential oil of Blumea lacera DC (Asteraceae) leaves from Nigeria. Flav Frag J 4:73–75CrossRefGoogle Scholar
  5. 5.
    Agarwal R, Singh R, Siddiqui I R, Singh J (1995) Triterpenoids and prenylated phenol glycosides from Blumea lacera. Phytochemistry 38:935–938CrossRefGoogle Scholar
  6. 6.
    Rao C B, Rao T N, Muralikrishna B (1997) Flavonoids from Blumea lacera. Planta Medica 31:235–237CrossRefGoogle Scholar
  7. 7.
    Pal R, Moitra SK, Chakravarti NN, Adhya RN (1972) Campesterol from Blumea lacera. Phytochemistry 11:1855–1857CrossRefGoogle Scholar
  8. 8.
    Bohlmann F, Zdero C (1969) Conyferyl alcohol derivative from Blumea lacera. Tetrahedron Lett 2:69–70CrossRefGoogle Scholar
  9. 9.
    Ragasa CY, Rideout JA, Sy JO, Alcachupas D, Inte VML, Coll JC (1997) Bioactive monoterpene glycosides from Erigeron linifolius. Phytochemistry 46:151–154CrossRefGoogle Scholar
  10. 10.
    Barberan FAT, Gil MI, Tomas F, Ferreres F, Arques A (1985) Flavonoid a glycones and glycosides from Teucrium gnaphalodes. J Nat Prod 48:859–860CrossRefGoogle Scholar
  11. 11.
    Guevara BQ, Recio BV (1985) Phytochemical, microbiological and pharmacological screening of medicinal plants. Acta Manilana Supplements, UST Research Center, Manila, pp 45–50Google Scholar

Copyright information

© The Japanese Society of Pharmacognosy and Springer 2007

Authors and Affiliations

  • Consolacion Y. Ragasa
    • 1
    Email author
  • Jeannie Wong
    • 2
  • John A. Rideout
    • 3
  1. 1.Chemistry Department and Center for Natural Sciences and Ecological ResearchDe La Salle UniversityManilaPhilippines
  2. 2.Chemistry DepartmentDe La Salle UniversityManilaPhilippines
  3. 3.School of Chemical and Biomedical SciencesCentral Queensland UniversityQueenslandAustralia

Personalised recommendations