Journal of Natural Medicines

, Volume 61, Issue 4, pp 474–475 | Cite as

Monoterpene glycoside and flavonoids from Blumea lacera

  • Consolacion Y. RagasaEmail author
  • Jeannie Wong
  • John A. Rideout
Natural Medicine Note


The dichloromethane extract of air-dried leaves of Blumea lacera (Asteraceae) afforded α-pinene-7β-O-β-d-2,6-diacetylglucopyranoside (1), 5,4′-dihydroxy-6,7,3′-trimethoxyflavone (2), and 3,5,4′-trihydroxy-6,7,3′-trimethoxyflavone (3). Compounds 13 showed moderate activity against Candida albicans, low activity against Trichophyton mentagrophytes, and were inactive against Aspergillus niger. Compounds 1 and 3 indicated low activity against Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus and were inactive against Bacillus subtilis, while 2 was inactive against all four bacteria tested.


Blumea lacera Asteraceae Monoterpene glycoside Flavonoids Antimicrobial 



The antimicrobial tests were conducted at the University of the Philippines-Natural Sciences Research Institute (UP-NSRI). A research grant from the National Research Council of the Philippines is gratefully acknowledged.


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Copyright information

© The Japanese Society of Pharmacognosy and Springer 2007

Authors and Affiliations

  • Consolacion Y. Ragasa
    • 1
    Email author
  • Jeannie Wong
    • 2
  • John A. Rideout
    • 3
  1. 1.Chemistry Department and Center for Natural Sciences and Ecological ResearchDe La Salle UniversityManilaPhilippines
  2. 2.Chemistry DepartmentDe La Salle UniversityManilaPhilippines
  3. 3.School of Chemical and Biomedical SciencesCentral Queensland UniversityQueenslandAustralia

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