Journal of Natural Medicines

, Volume 61, Issue 4, pp 387–390 | Cite as

Effects of silkworm powder on glucose absorption by human intestinal epithelial cell line Caco-2

Original Paper


Inhibitors of glucose absorption play an important role in the treatment of diabetes. In this research, we report that silkworm powder has inhibitory effects on glucose absorption in human intestinal epithelial cells. Silkworm powder inhibited α-glucosidase activation and glucose transporter (SGLT1) expression. These results suggest that silkworm powder can be used as a natural functional food for the prevention and alleviation of type-2 diabetes.


Silkworm powder Caco-2 cells Glucose absorption α-Glucosidase Sodium-dependent glucose transporter Type-2 diabetes 


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Copyright information

© The Japanese Society of Pharmacognosy and Springer 2007

Authors and Affiliations

  1. 1.Graduate School of Life and Environmental SciencesUniversity of TsukubaTsukubaJapan
  2. 2.CB Japan, Co., LtdTsurugashimaJapan

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