, 38:40 | Cite as

Effect of resistance training on muscular strength and indicators of abdominal adiposity, metabolic risk, and inflammation in postmenopausal women: controlled and randomized clinical trial of efficacy of training volume

  • Paulo Ricardo Prado Nunes
  • Larissa Corrêa Barcelos
  • Anselmo Alves Oliveira
  • Roberto Furlanetto Júnior
  • Fernanda Maria Martins
  • Cláudio Lera Orsatti
  • Elisabete Aparecida Mantovani Rodrigues Resende
  • Fábio Lera Orsatti


This study evaluated the effect of resistance training (RT) volume on muscular strength and on indicators of abdominal adiposity, metabolic risk, and inflammation in post-menopausal women (PW). Thirty-two volunteers were randomly allocated into the following three groups: control (CT, no exercise, n = 11), low-volume RT (LV, three sets/exercise, n = 10), and high-volume RT (HV, six sets/exercise, n = 11). The LV and HV groups performed eight exercises at 70 % of one maximal repetition, three times a week, for 16 weeks. Muscular strength and indicators of abdominal adiposity, metabolic risk, and inflammation were measured at baseline and after 16 weeks. No differences were found in baseline measures between the groups. The PW showed excess weight and fat percentage (F%), large waist circumference (WC), high waist-hip ratio (WHR), and hypercholesterolemia and borderline values of glycated hemoglobin (HbA1c%). Following the RT, a similar increase in muscle strength and reduction in F% from baseline were found in both trained groups. In HV, a decrease in total cholesterol, LDL-c, WC, and WHR was noted. Moreover, the HV showed a lower change (delta%) of interleukin-6 (IL-6) when compared to CT (HV = 11.2 %, P 25–75 = −7.6–28.4 % vs. CT = 99.55 %, P 25–75 = 18.5–377.0 %, p = 0.049). In LV, a decrease was noted for HbA1c%. There were positive correlations (delta%) between WHR and IL-6 and between IL-6 and TC. These results suggest that while a low-volume RT improves HbA1c%, F%, and muscular strength, a high-volume RT is necessary to improve indicators of abdominal adiposity and lipid metabolism and also prevent IL-6 increases in PW.


Exercise Sarcopenia Obesity Glycosylated hemoglobin Menopause 



We thank Camila Botelho Miguel and Luanna Margato for assisting us with the subjects. This investigation was supported by Fundação de Amparo à Pesquisa do estado de Minas Gerais–FAPEMIG, by Fundação de Ensino e Pesquisa de Uberaba–FUNEPU, and by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior–CAPES.


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Copyright information

© American Aging Association 2016

Authors and Affiliations

  • Paulo Ricardo Prado Nunes
    • 1
  • Larissa Corrêa Barcelos
    • 1
  • Anselmo Alves Oliveira
    • 1
  • Roberto Furlanetto Júnior
    • 1
  • Fernanda Maria Martins
    • 1
  • Cláudio Lera Orsatti
    • 1
  • Elisabete Aparecida Mantovani Rodrigues Resende
    • 1
  • Fábio Lera Orsatti
    • 1
    • 2
  1. 1.Postgraduate Course of Physical Education, Exercise Biology Laboratory (BioEx)Federal University of Triângulo Mineiro (UFTM)UberabaBrazil
  2. 2.Department of Sport Sciences, Health Science InstituteFederal University of Triangulo Mineiro (UFTM)UberabaBrazil

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