Effect of resistance training on C-reactive protein, blood glucose and lipid profile in older women with differing levels of RT experience
- 359 Downloads
The purpose of this study was to analyze the effects of a progressive resistance training (RT) program on C-reactive protein (CRP), blood glucose (GLU), and lipid profile in older women with differing levels of RT experience. Sixty-five older women (68.9 ± 6.1 years, 67.1 ± 13.1 kg) were separated according to RT experience: an advanced group composed by 35 participants who previously carried out 24 weeks of RT and a novice group composed by 30 participants without previous experience in RT (n = 30). Both groups performed a RT program comprised of eight exercises targeting all the major muscles. Training was carried out 3 days/week for 8 weeks. Serum triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), GLU, and CRP concentrations were determined pre- and post- intervention after 12 h fasting. A significant group by time interaction (P < 0.05) for the TC (novice = −1.9 % vs. advanced = 1.0 %), and CRP (novice = −22.9 % vs. advanced = −54.5 %) was observed. A main effect of time (P < 0.05) was identified for the GLU (novice = −2.6 % vs. advanced = −6.6 %), TG (novice = −12.9 % vs. advanced = −5.7 %), HDL-C (novice = +6.7 % vs. advanced = +2.6 %), and LDL-C (novice = −34.0 % vs. advanced = −25.4 %). These results suggest that RT improves the metabolic profile of older women and that training for a longer period of time seems to produce more pronounced reductions mainly on CRP.
KeywordsAging C-reactive protein Lipoproteins Strength training
Compliance with ethical standards
Written informed consent was obtained from all participants after a detailed description of study procedures was provided. This investigation was conducted according to the Declaration of Helsinki and was approved by the local University Ethics Committee.
- Cohen J (1988) Statistical power analysis for the behavioral sciences. Lawrence Erlbaum Associate, HillsdaleGoogle Scholar
- Donges CE, Duffield R, Guelfi KJ, Smith GC, Adams DR, Edge JA (2013) Comparative effects of single-mode vs. duration-matched concurrent exercise training on body composition, low-grade inflammation, and glucose regulation in sedentary, overweight, middle-aged men. Appl Physiol Nutr Metab 38:779–788. doi: 10.1139/apnm-2012-0443 PubMedCrossRefGoogle Scholar
- Garber CE et al. (2011) American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc 43:1334–1359. doi: 10.1249/MSS.0b013e318213fefb PubMedCrossRefGoogle Scholar
- Kengne AP, Batty GD, Hamer M, Stamatakis E, Czernichow S (2012) Association of C-reactive protein with cardiovascular disease mortality according to diabetes status: pooled analyses of 25,979 participants from four U.K. prospective cohort studies. Diabetes Care 35:396–403. doi: 10.2337/dc11-1588 PubMedPubMedCentralCrossRefGoogle Scholar
- Mann S, Beedie C, Jimenez A (2014) Differential effects of aerobic exercise, resistance training and combined exercise modalities on cholesterol and the lipid profile: review, synthesis and recommendations. Sports Med 44:211–221. doi: 10.1007/s40279-013-0110-5 PubMedPubMedCentralCrossRefGoogle Scholar
- Mavros Y et al. (2014) Reductions in C-reactive protein in older adults with type 2 diabetes are related to improvements in body composition following a randomized controlled trial of resistance training. J Cachexia Sarcopenia Muscle 5:111–120. doi: 10.1007/s13539-014-0134-1 PubMedPubMedCentralCrossRefGoogle Scholar
- Simonavice E, Liu PY, Ilich JZ, Kim JS, Arjmandi B, Panton LB (2014) The effects of a 6-month resistance training and dried plum consumption intervention on strength, body composition, blood markers of bone turnover, and inflammation in breast cancer survivors. Appl Physiol Nutr Metab 39:730–739. doi: 10.1139/apnm-2013-0281 PubMedCrossRefGoogle Scholar