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Analysis of multiclass organic pollutant in municipal landfill leachate by dispersive liquid-liquid microextraction and comprehensive two-dimensional gas chromatography coupled with mass spectrometry

  • Mihail Simion Beldean-GaleaEmail author
  • Jerôme Vial
  • Didier Thiébaut
  • Maria-Virginia Coman
Research Article

Abstract

We propose a simple, fast, and inexpensive method for the analyses of 72 organic compounds in municipal landfill leachate, based on dispersive liquid-liquid microextraction and comprehensive two-dimensional gas chromatography coupled with mass spectrometry. Forty-one organic compounds belonging to several classes including hydrocarbons, mono- and polyaromatic hydrocarbons, carbonyl compounds, terpenes, terpenoids, phenols, amines, and phthalates, covering a wide range of physicochemical properties and linked to municipal landfill leachate, were quantitatively determined. Another 31 organic compounds such as indoles, pyrroles, glycols, organophosphate flame retardants, aromatic amines and amides, pharmaceuticals, and bisphenol A have been identified based on their mass spectra. The developed method provides good performances in terms of extraction recovery (63.8–127%), intra-day and inter-day precisions (< 7.7 and < 13.9 respectively), linearity (R2 between 0.9669 and 0.9999), detection limit (1.01–69.30 μg L-1), quantification limit (1.87–138.6 μg L-1), and enrichment factor (69.6–138.5). Detailed information on the organic pollutants contained in municipal landfill leachate could be obtained with this method during a 40-min analysis of a 4-mL leachate sample, using only 75 μL of extraction solvent.

Keywords

Municipal landfill leachate Organic pollutants Dispersive liquid-liquid microextraction GC×GC-qMS 

Notes

Acknowledgments

This work was performed in the frame of the Romania—France Bilateral Cooperation, Program Brâncuși, Project No. 774/2014 funded by UEFISCDI—Romania, Project No. 32654NJ funded by Campus-France and Program Chaire Joliot founded by ESPCI-Paris.

Supplementary material

11356_2019_7064_MOESM1_ESM.docx (3.4 mb)
ESM 1 (DOCX 3637 kb).

References

  1. Abdulra’uf LB, Tan GH (2013) Multivariate study of parameters in the determination of pesticide residues in apple by headspace solid phase microextraction coupled to gas chromatography–mass spectrometry using experimental factorial design. Food Chem 141:4344–4348.  https://doi.org/10.1016/j.foodchem.2013.07.022 CrossRefGoogle Scholar
  2. Adahchour M, Beens J, Vreuls RJJ, Brinkman UAT (2006) Recent developments in comprehensive two-dimensional gas chromatography (GC×GC): I. Introduction and instrumental set-up. TrAC-Trends Anal Chem 25(5):438–454.  https://doi.org/10.1016/j.trac.2006.03.002 CrossRefGoogle Scholar
  3. Alinat E, Delaunay N, Archer X, Vial J, Gareil P (2015) Multivariate optimization of the denitration reaction of nitrocelluloses for safer determination of their nitrogen content. Forensic Sci Int 250:68–76.  https://doi.org/10.1016/j.forsciint.2015.03.001 CrossRefGoogle Scholar
  4. Asati A, Satyanarayana GNV, Patel DK (2017) Comparison of two microextraction methods based on solidification of floating organic droplet for the determination of multiclass analytes in river water samples by liquid chromatography tandem mass spectrometry using Central Composite Design. J Chromatogr A 1513:157–171.  https://doi.org/10.1016/j.chroma.2017.07.048 CrossRefGoogle Scholar
  5. Baderna D, Maggioni S, Boriani E, Gemmab S, Molteni M, Lombardo A, Colombo A, Bordonali S, Rotella G, Lodi M, Benfenati E (2011) A combined approach to investigate the toxicity of an industrial landfill’s leachate: chemical analyses, risk assessment and in vitro assays. Environ Res 111:603–613.  https://doi.org/10.1016/j.envres.2011.01.015 CrossRefGoogle Scholar
  6. Beldean-Galea MS, Vial J, Thiebaut D (2013) Development of a screening method for the determination of xenobiotic organic pollutants in municipal landfill leachate using solvent extraction and comprehensive GCxGC-qMS analysis. Cent Eur J Chem 11:1563–1574.  https://doi.org/10.2478/s11532-013-0298-0 CrossRefGoogle Scholar
  7. Beldean-Galea MS, Thiebaut D, Vial J, Coman V (2017) Identification of complex volatile organic compounds in municipal landfill leachate by head space solid phase microextraction and GCxGC-qMS analysis. Stud U Babes-Bol Che LXII(3):35–44.  https://doi.org/10.24193/subbchem.2017.3.03 CrossRefGoogle Scholar
  8. Borrás E, Tortajada-Genaro LA, Muñoz A (2016) Determination of reduced sulphur compounds in air samples for the monitoring of malodour caused by landfills. Talanta 148:472–477.  https://doi.org/10.1016/j.talanta.2015.11.021 CrossRefGoogle Scholar
  9. Budi S, Suliasih BA, Othman MS, Heng LY, Surif S (2016) Toxicity identification evaluation of landfill leachate using fish, prawn and seed plant. Waste Manag 55:231–237.  https://doi.org/10.1016/j.wasman.2015.09.022 CrossRefGoogle Scholar
  10. Callao MP (2014) Multivariate experimental design in environmental analysis. TrAC-Trends Anal Chem 62:86–92.  https://doi.org/10.1016/j.trac.2014.07.009 CrossRefGoogle Scholar
  11. Chormey DS, Bodur S, Baskın D, Fırat M, Bakırdere S (2018) Accurate and sensitive determination of selected hormones, endocrine disruptors, and pesticides by gas chromatography–mass spectrometry after the multivariate optimization of switchable solvent liquid-phase microextraction. J Sep Sci 41:2895–2902.  https://doi.org/10.1002/jssc.201800223 CrossRefGoogle Scholar
  12. de Vos J, Dixon R, Vermeulen G, Gorst-Allman P, Cochran J, Rohwer E, Focant JF (2011) Comprehensive two-dimensional gas chromatography time of flight mass spectrometry (GCxGC–TOFMS) for environmental forensic investigations in developing countries. Chemosphere 82:1230–1239.  https://doi.org/10.1016/j.chemosphere.2010.12.039 CrossRefGoogle Scholar
  13. Deblonde GJP, Chagnes A, Cote G, Vial J, Rivals I, Delaunay N (2016) Development of a capillary electrophoresis method for the analysis in alkaline media as polyoxoanions of two strategic metals: niobium and tantalum. J Chromatogr A 1437:210–218.  https://doi.org/10.1016/j.chroma.2016.01.075 CrossRefGoogle Scholar
  14. Dil EA, Ghaedi M, Asfaram A, Zare F, Mehrabi F, Sadeghfar F (2017) Comparison between dispersive solid-phase and dispersive liquid–liquid microextraction combined with spectrophotometric determination of malachite green in water samples based on ultrasound-assisted and preconcentration under multi-variable experimental design optimization. Ultrason Sonochem 39:374–383.  https://doi.org/10.1016/j.ultsonch.2017.05.011 CrossRefGoogle Scholar
  15. Ding Y, Cai C, Hu B, Xu Y, Zheng X, Chen Y, Wu W (2012) Characterization and control of odorous gases at a landfill site: a case study in Hangzhou, China. Waste Manag 32:317–326.  https://doi.org/10.1016/j.wasman.2011.07.016 CrossRefGoogle Scholar
  16. Eggen T, Moeder M, Arukwe A (2010) Municipal landfill leachates: a significant source for new and emerging pollutants. Sci Total Environ 408:5147–5157.  https://doi.org/10.1016/j.scitotenv.2010.07.049 CrossRefGoogle Scholar
  17. Ferey L, Delaunay N, Rutledge DN, Huertas A, Raoul Y, Gareil P, Vial J (2013) Use of response surface methodology to optimize the simultaneous separation of eight polycyclic aromatic hydrocarbons by capillary zone electrophoresis with laser-induced fluorescence detection. J Chromatogr A 1302:181–190.  https://doi.org/10.1016/j.chroma.2013.06.027 CrossRefGoogle Scholar
  18. Fuertes I, Gomez-Lavín S, Elizalde MP, Urtiaga A (2017) Perfluorinated alkyl substances (PFASs) in northern Spain municipal solid waste landfill leachates. Chemosphere 168:399–407.  https://doi.org/10.1016/j.chemosphere.2016.10.072 CrossRefGoogle Scholar
  19. Ghosh P, Thakur IS, Kaushik A (2017) Bioassays for toxicological risk assessment of landfill leachate: a review. Ecotoxicol Environ Saf 141:259–270.  https://doi.org/10.1016/j.ecoenv.2017.03.023 CrossRefGoogle Scholar
  20. Guidelines for validation of analytical methods for non-agricultural pesticide active ingredients and products (n.d.) Available at: http://www.hse.gov.uk/biocides/copr/pdfs/validation.pdf (accessed: January 20, 2019)
  21. Hashemi B, Zohrabi P, Kim KH, Shamsipur M, Deep A, Hong J (2017) Recent advances in liquid-phase microextraction techniques for the analysis of environmental pollutants. TrAC-Trends Anal Chem 97:83–95.  https://doi.org/10.1016/j.trac.2017.08.014 CrossRefGoogle Scholar
  22. Huang JH, Ilgen G, Vogel D, Michalzik B, Hantsch S, Tennhardt L, Bilitewski B (2009) Emissions of inorganic and organic arsenic compounds via the leachate pathway from pretreated municipal waste materials: a landfill reactor study. Environ Sci Technol 43:7092–7097.  https://doi.org/10.1021/es901605q CrossRefGoogle Scholar
  23. Huset CA, Barlaz MA, Barofsky DF, Field JA (2011) Quantitative determination of fluorochemicals in municipal landfill leachates. Chemosphere 82:1380–1386.  https://doi.org/10.1016/j.chemosphere.2010.11.072 CrossRefGoogle Scholar
  24. Ieda T, Hashimoto S, Isobe T, Kunisue T, Tanabe S (2019) Evaluation of a data-processing method for target and non-target screening using comprehensive two-dimensional gas chromatography coupled with high-resolution time-of-flight mass spectrometry for environmental samples. Talanta 194:461–468.  https://doi.org/10.1016/j.talanta.2018.10.050 CrossRefGoogle Scholar
  25. Jernberg J, Pellinen J, Rantalainen AL (2013) Qualitative non-target analysis of landfill leachate using gas chromatography time-of-flight mass spectrometry. Talanta 103:384–391.  https://doi.org/10.1016/j.talanta.2012.10.084 CrossRefGoogle Scholar
  26. Khalil C, Al Hageh C, Korfali S, Khnayzer RS (2018) Municipal leachates health risks: Chemical and cytotoxicity assessment from regulated and unregulated municipal dumpsites in Lebanon. Chemosphere 208:1–13.  https://doi.org/10.1016/j.chemosphere.2018.05.151 CrossRefGoogle Scholar
  27. Kumarathilaka P, Jayawardhana Y, Basnayake BFA, Mowjood MIM, Nagamori M, Saito T, Kawamoto K, Vithanage M (2016) Characterizing volatile organic compounds in leachate from Gohagoda municipal solid waste dumpsite, Sri Lanka. Groundwater Sustainable Dev 2-3:1–6.  https://doi.org/10.1016/j.gsd.2016.04.001 CrossRefGoogle Scholar
  28. Mavakala BK, Le Faucheur S, Mulaji CK, Laffite A, Devarajan N, Biey EM, Giuliani G, Otamonga JP, Kabatusuila P, Mpiana PT, Poté J (2016) Leachates draining from controlled municipal solid waste landfill: detailed geochemical characterization and toxicity tests. Waste Manag 55:238–248.  https://doi.org/10.1016/j.wasman.2016.04.028 CrossRefGoogle Scholar
  29. Mukherjee S, Mukhopadhyay S, Hashim MA, Gupta BS (2015) Contemporary environmental issues of landfill leachate: assessment and remedies. Crit Rev Environ Sci Technol 45:472–590.  https://doi.org/10.1080/10643389.2013.876524 CrossRefGoogle Scholar
  30. Muscalu AM, Górecki T (2018) Comprehensive two-dimensional gas chromatography in environmental analysis. TrAC-Trends Anal Chem 106:225–245.  https://doi.org/10.1016/j.trac.2018.07.001 CrossRefGoogle Scholar
  31. Öman CB, Junestedt C (2008) Chemical characterization of landfill leachates—400 parameters and compounds. Waste Manag 28:1876–1891.  https://doi.org/10.1016/j.wasman.2007.06.018 CrossRefGoogle Scholar
  32. Pastore C, Barca E, Del Moro G, Di Iaconi C, Loos M, Singer HP, Mascolo G (2018) Comparison of different types of landfill leachate treatments by employment of non-target screening to identify residual refractory organics and principal component analysis. Sci Total Environ 635:984–994.  https://doi.org/10.1016/j.scitotenv.2018.04.135 CrossRefGoogle Scholar
  33. Pivato A, Gaspari L (2005) Acute toxicity test of leachates from traditional and sustainable landfills using luminescent bacteria. Waste Manag 26:1148–1155.  https://doi.org/10.1016/j.wasman.2005.10.008 CrossRefGoogle Scholar
  34. Prebihalo S, Brockman A, Cochran J, Dorman FL (2015) Determination of emerging contaminants in wastewater utilizing comprehensive two-dimensional gas-chromatography coupled with time-of-flight mass spectrometry. J Chromatogr A 1419:109–115.  https://doi.org/10.1016/j.chroma.2015.09.080 CrossRefGoogle Scholar
  35. Qi C, Huang J, Wang B, Deng S, Wang Y, Yu G (2018) Contaminants of emerging concern in landfill leachate in China: a review. Emerg Contam 4(1):1–10.  https://doi.org/10.1016/j.emcon.2018.06.001 CrossRefGoogle Scholar
  36. Renou S, Givaudan JG, Poulain S, Dirassouyan F, Moulin P (2008) Landfill leachate treatment: review and opportunity. J Hazard Mater 150:468–493.  https://doi.org/10.1016/j.jhazmat.2007.09.077 CrossRefGoogle Scholar
  37. Thermo Fischer chemical product data (n.d.) https://www.fishersci.fr/chemicalProductData_uk/welcome.do (accessed on July 07, 2019)
  38. Tigini V, Prigione V, Varese GC (2014) Mycological and ecotoxicological characterization of landfill leachate before and after traditional treatments. Sci Total Environ 487:335–341.  https://doi.org/10.1016/j.scitotenv.2014.04.026 CrossRefGoogle Scholar
  39. Wang Y, You J, Ren R, Xiao Y, Gao S, Zhang H, Yu A (2010) Determination of triazines in honey by dispersive liquid–liquid microextraction high-performance liquid chromatography. J Chromatogr A 1217:4241–4246.  https://doi.org/10.1016/j.chroma.2010.03.031 CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2020

Authors and Affiliations

  1. 1.Faculty of Environmental Science and EngineeringBabeș-Bolyai UniversityCluj-NapocaRomania
  2. 2.UMR CNRS CBI, PSL Research InstituteÉcole Supérieure de Physique et de Chimie Industrielles de la Ville de ParisParisFrance
  3. 3.“Raluca Ripan” Institute for Research in ChemistryBabeș-Bolyai UniversityCluj-NapocaRomania

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