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Potential dietary factors for reducing lead burden of Chinese preschool children

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Dietary approaches to treat children’s low lead exposure are implemented routinely in China, while evidence for the effect could not be provided until now. The aim of this study was to examine the relationship between diets including nutrition supplementation and blood lead level of preschool children of China. In total, 17,859 preschool children from 14 cities were recruited, and their social-demography, living environment, and dietary intakes were collected, and capillary blood sample was tested for lead concentration. The average blood lead concentration was 34.5 μg/L, and after adjusting children’s social-demography factors, the consumption of milk or dairy production, fruits, and calcium supplementation had negative dose-response relationships with blood lead level. Conversely, intake of iron-rich food and supplementation was not associated. Further studies are needed to prove the causal relationships.

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Fig. 1



Blood lead levels


Confidence interval


Geometric mean


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Tao Li wrote the first draft of this paper. All authors contributed to the intellectual content and approved the final version. Yaohua Dai is the guarantor.


This study was financially supported by Beijing Bohui Innovation Technology Co., Ltd.

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Correspondence to Yaohua Dai.

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The authors declare that they have no conflict of interest.

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This study was approved by the Ethics Committee of the Capital Institute of Pediatrics.


The funding agencies have no role in the study design, implementation, data analysis, and interpretation.

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Li, T., Zhang, S., Tan, Z. et al. Potential dietary factors for reducing lead burden of Chinese preschool children. Environ Sci Pollut Res 26, 22922–22928 (2019). https://doi.org/10.1007/s11356-019-05527-x

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  • Preschool
  • Blood lead
  • Dietary
  • China