Mobile phones emit a radiofrequency radiation (RFR) that might have adverse health effects. We aimed to investigate the possible protective effects of aluminium foil (AF) as a physical shield against the RFR from mobile phones on the blood parameters and the myocardium in rats. The effects of whole body 2100 MHz with 0.84–1.86 W/kg of SAR, 4 h/day for 30 days Global System for Mobile Communications (GSM)-RFR exposure for 4 h/day for 30 days on blood parameters (i.e. haemoglobin, leucocytes, thrombocytes, erythrocyte sedimentation rate, white blood cell differential count, corticosterone, CKMB), and the histology of myocardium were investigated. Three-month-old male rats (n = 32) were studied and randomised equally in the following four groups: K1 (non-AF non-RFR control), K2 (AF non-RFR control), P1 (non-AF RFR-exposed), P2 (AF RFR-exposed). Data were analysed with level of significance of p < 0.05. In P1, lower leucocytes and neutrophils counts with high corticosterone levels were found compared with the control groups, whilst a significantly higher CKMB was observed compared with P2 (p = 0.034). Lower cardiomyocyte counts congruent to the area fraction of the non-fibrotic myocardium were observed in P1 compared with the other groups (p < 0.01). AF might decrease the inflammatory-oxidative stress on rodent’s blood cells and myocardium induced by the exposures of radiofrequency radiation of the mobile phones.
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Black DR, Heynick LN (2003) Radiofrequency (RF) effects on blood cells, cardiac, endocrine, and immunological functions. Bioelectromagnet Suppl 6:S187–S195
Daunoravicius D, Besusparis J, Zurauskas E, Laurinaviciene A, Bironaite D, Pankuweit S, Plancoulaine B, Herlin P, Bogomolovas J, Grabauskiene V, Laurinavicius A (2014) Quantification of myocardial fibrosis by digital image analysis and interactive stereology. BMC Diagn Pathol 9:114
De Iuliis GN, Newey RJ, King BV et al (2009) Mobile phone radiation induces reactive oxygen species production and DNA damage in human spermatozoa in vitro. PLoS One 4(7):e6446
Frohlich ED (2001) Fibrosis and ischemia: the real risks in hypertensive heart disease. Am J Hypertens 14:194S–199S
Gumral N, Saygin M, Asci H et al (2016) The effects of electromagnetic radiation (2450 MHz wireless devices) on the heart and blood tissue: role of melatonin. Bratisl Med J 117:665–671
Hales PW, Burton RAB, Bollensdorff C, Mason F, Bishop M, Gavaghan D, Kohl P, Schneider JE (2011) Progressive changes in T1, T2 and left-ventricular histo-architecture in the fixed and embedded rat heart. NMR Biomed 24:836–843
Huang AT, Mold NG (1980) Imunologic and hematopoietic alterations by 2450 MHz electromagnetic radiation. Bioelectromagnetic 1(1):77–87
Kalanjati VP, Wixey JA, Miller SM, Colditz PB, Bjorkman ST (2017) GABAA receptor expression and white matter disruption in intrauterine growth restricted piglets. Int J Dev Neurosci 59:1–9
Kovacic P, Somanathan R (2010) Electromagnetic fields: mechanism, cell signaling, other bioprocesses, toxicity, radicals, antioxidants and beneficial effects. J Recept Signal Transduct Res 30:214–226
Mahdavi SM, Sahraei H, Yaghmaei P, Tavakoli H (2014) Effects of electromagnetic radiation exposure on stress-related behaviors and stress hormones in male Wistar rats. Biomol Ther 22:570–576
Mailankot M, Kunnath AP, Jayalekshmi H, Koduru B, Valsalan R (2009) Radio frequency electromagnetic radiation (RF-EMR) from GSM (0.9/1.8GHz) mobile phones induces oxidative stress and reduces sperm motiliy in rats. Clinics 64:561–565
Nadeljkovic XS, Gokce N, dan Loscalzo J (2003) Mechanisms of oxidative stress and vascular dysfunction. Postrad Med J 79:195–200
Neumann E, Schaefer RM, Wang Y et al (1982) Gene transfer into mouse lyoma cells by electroporation in high electric fields. EMBO J 1:841–845
Safer AM (2017) A quantitative description of lipid and extracellular matrix proteinaceous fibers in hepatic fibrosis of a rat model by ImageJ using nano-images. J Nanomed Nanotechnol 8:1–6
Sirswal A, Dewan MK (2016) Modeling effect of electromagnetic interference on cardiovascular system. IJRDASE 9:1–7
Smialowicz RJ, Weil CM, Marsh P et al (1981) Biological effects on long-term exposure of rats to 970-MHz radiofrequency radiation. Bioelectromagnetic 981:279–284
Sobrino-Marquez JM, Grande-Trillo A, Cantero-Perez EM et al (2018) Prognostic value of blood panel parameters in patients with dilated cardiomyopathy and advanced heart failure. Transplant Proc 50:650–652
Venkataraman P, Khrisnamoorthy G, Selvakumar K et al (2009) Oxidative stress alters creatine kinase system in serum and brain regions of polychlorynated biphenyl (aroclor 1254)-exposed rats: protective role of melatonin. Basic Clin Pharmacol Toxycol 105:92–97
Willerson JT, Ridker PM (2004) Inflammation as a cardiovascular risk factor. Circulation 109(Suppl II):II2–II10
Thank you to all colleagues and The Head of Department of Anatomy and Histology, Faculty of Medicine, Universitas Airlangga. Special appreciation to I. Farindra, D. Krismashogi, and E. Rambung for help and supports.
This study was funded by Universitas Airlangga.
This study was approved by the Komite Etik Penelitian Kesehatan (Ethic Committee on Health Research) of the Faculty of Medicine, Universitas Airlangga (No. 141/EC/KEPK/FKUA/2018).
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Kalanjati, V.P., Purwantari, K.E. & Prasetiowati, L. Aluminium foil dampened the adverse effect of 2100 MHz mobile phone–induced radiation on the blood parameters and myocardium in rats. Environ Sci Pollut Res 26, 11686–11689 (2019). https://doi.org/10.1007/s11356-019-04601-8
- Oxidative stress