Fate and toxicity of silver nanoparticles in freshwater from laboratory to realistic environments: a review
- 58 Downloads
The fate and risk assessment of silver nanoparticles (Ag NPs) is an important environmental health issue. The toxic effects, mechanisms, and modes of action of Ag NPs on aquatic organisms have been extensively determined in the laboratory. However, knowledge gaps and discrepancies exist between laboratory studies and realistic environmental research; such inconsistencies hinder the development of health and safety regulations. To bridge these gaps, this review summarizes how environmental conditions and the physicochemical properties of Ag NPs affect the inconsistent findings between laboratory studies and realistic environmental research. Moreover, this paper systematically reviews different toxic effects of Ag NPs in a realistic environment and compares these effects with those in the laboratory, which is helpful for assessing the environmental fate and risk of Ag NPs. The hazardous effects of Ag NPs on the whole aquatic ecosystem with low concentrations (μg L−1) and long-term periods (months to years) are detailed. Furthermore, two perspectives of future toxicity studies of Ag NPs in realistic freshwater environments are emphasized.
KeywordsFate Toxicity Silver nanoparticles Environmental risk
We acknowledge financial support from the Joint Funds of the National Natural Science Foundation of China (No. U1804109), the Scientific Research and Service Platform Fund of Henan Province (No. 2016151), the scientific and technological innovation team of water ecological security for the Water Source Region of Mid-line of the South-to-North Diversion Project of Henan Province (No. 17454), the Foundation of Henan educational committee (No. 19A330003), and the Foundation of Nanyang Normal University (No. 18023). We greatly thank the anonymous reviewers for their helpful comments.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
- Chen S, Goode AE, Sweeney S, Theodorou IG, Thorley AJ, Ruenraroengsak P, Chang Y, Gow A, Schwander S, Skepper J, Zhang J, Shaffer MS, Chung KF, Tetley TD, Ryan MP, Porter AE (2013) Sulfidation of silver nanowires inside human alveolar epithelial cells: a potential detoxification mechanism. Nanoscale 5:9839–9847CrossRefGoogle Scholar
- Colman BP, Arnaout CL, Anciaux S, Gunsch CK, Hochella MF Jr, Kim B, Lowry GV, McGill BM, Reinsch BC, Richardson CJ, Unrine JM, Wright JP, Yin L, Bernhardt ES (2013) Low concentrations of silver nanoparticles in biosolids cause adverse ecosystem responses under realistic field scenario. PLoS One 8:e57189CrossRefGoogle Scholar
- Gliga AR, Skoglund S, Wallinder IO, Fadeel B, Karlsson HL (2014) Size-dependent cytotoxicity of silver nanoparticles in human lung cells: the role of cellular uptake, agglomeration and Ag release. Part Fibre Toxicol 11:11Google Scholar
- Lowry GV, Espinasse BP, Badireddy AR, Richardson CJ, Reinsch BC, Bryant LD, Bone AJ, Deonarine A, Chae S, Therezien M, Colman BP, Hsu-Kim H, Bernhardt ES, Matson CW, Wiesner MR (2012) Long-term transformation and fate of manufactured Ag nanoparticles in a simulated large scale freshwater emergent wetland. Environ Sci Technol 46:7027–7036CrossRefGoogle Scholar
- Peijnenburg WJGM, Baalousha M, Chen J, Chaudry Q, Von der kammer F, Kuhlbusch TAJ, Lead J, Nickel C, Quik JTK, Renker M, Wang Z, Koelmans AA (2015) A review of the properties and processes determining the fate of engineered nanomaterials in the aquatic environment. Crit Rev Environ Sci Technol 45:2084–2134CrossRefGoogle Scholar
- Scanlan LD, Reed RB, Loguinov AV, Antczak P, Tagmount A, Aloni S, Nowinski DT, Luong P, Tran C, Karunaratne N, Pham D, Lin XX, Falciani F, Higgins CP, Ranville JF, Vulpe CD, Gilbert B (2013) Silver nanowire exposure results in internalization and toxicity to Daphnia magna. ACS Nano 7:10681–10694CrossRefGoogle Scholar
- Sohn EK, Johari SA, Kim TG, Kim JK, Kim E, Lee JH, Chung YS, Yu IJ (2015) Aquatic toxicity comparison of silver nanoparticles and silver nanowires. Biomed Res Int 2015:12Google Scholar
- Taylor C, Matzke M, Kroll A, Read DS, Svendsen C, Crossley A (2016) Toxic interactions of different silver forms with freshwater green algae and cyanobacteria and their effects on mechanistic endpoints and the production of extracellular polymeric substances. Environ Sci Nano 3:396–408CrossRefGoogle Scholar