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Silkworm, Bombyx mori, as an alternative model organism in toxicological research


Silkworms, Bombyx mori , are a promising model animal in health safety and environmental pollution assessment due to their sensitivity to chemical compounds like pesticides, drugs, and heavy metals, in addition to other features like their low cost and body characteristics and their full genome sequencing. In this review, we summarize the silkworm advantages as a model organism in toxicological research.

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This work was supported by the Project of the Priority Academic Program Development of Jiangsu Higher Education Institutions, the National Natural Science Foundation of China (Nos. 31572467, 31272507, 31570150, 31602008, and 31550110210), the National Science Foundation of Jiangsu Province (BK20150495), Postdoctoral Science Foundation of Jiangsu Province (1501012B), and Postgraduate Research and Innovation Project of Jiangsu Province (No. CXLX12-0671).

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Correspondence to Chen Keping.

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Responsible editor: Philippe Garrigues

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Abdelli, N., Peng, L. & Keping, C. Silkworm, Bombyx mori, as an alternative model organism in toxicological research. Environ Sci Pollut Res 25, 35048–35054 (2018). https://doi.org/10.1007/s11356-018-3442-8

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  • Silkworm
  • Model organism
  • Toxicity