Advertisement

Environmental Science and Pollution Research

, Volume 24, Issue 25, pp 20261–20272 | Cite as

Time series analysis of ambient air pollution effects on daily mortality

  • Yinsheng Guo
  • Yue Ma
  • Yanwei Zhang
  • Suli Huang
  • Yongsheng Wu
  • Shuyuan Yu
  • Fei ZouEmail author
  • Jinquan ChengEmail author
Research Article

Abstract

Although the growths of ambient pollutants have been attracting public concern, the characteristic of the associations between air pollutants and mortality remains elusive. Time series analysis with a generalized additive model was performed to estimate the associations between ambient air pollutants and mortality outcomes in Shenzhen City for the period of 2012–2014. The results showed that nitrogen dioxide (NO2)-induced excess risks (ER) of total non-accidental mortality and cardiovascular mortality were significantly increased (6.05% (95% CI 3.38%, 8.78%); 6.88% (95% CI 2.98%, 10.93%), respectively) in interquartile range (IQR) increase analysis. Also, these associations were strengthened after adjusting for other pollutants. Moreover, similar associations were estimated for sulfur dioxide (SO2), particulate matter with an aerodynamic diameter of <10 μm (PM10), and total non-accidental mortality. There were significant higher ERs of associations between PM10 and mortality for men than women; while there were significant higher ERs of associations between PM10/NO2 and mortality for elders (65 or elder) than youngers (64 or younger). Season analyses showed that associations between NO2 and total non-accidental mortality were more pronounced in hot seasons than in warm seasons. Taken together, NO2 was positively associated with total non-accidental mortality and cardiovascular mortality in Shenzhen even when the concentrations were below the ambient air quality standard. Policy measures should aim at reducing residents’ exposure to anthropogenic NO2 emissions.

Keywords

Air pollutants Cardiovascular mortality Non-accidental mortality Respiratory mortality Time series analysis 

Notes

Acknowledgements

Authors thank the Shenzhen Environmental Monitoring Center and Meteorological Bureau of Shenzhen Municipality for supplying the air monitoring data. This work was supported by the National Natural Science Foundation of China (Grant No. 81573242) and China Postdoctoral Science Foundation funded project (Grant No. 2016M602537).

Compliance with ethical standards

Conflict of interest

The authors’ declare that there is no conflict of interest.

Supplementary material

11356_2017_9502_Fig4_ESM.gif (188 kb)
Supplementary Fig. 1

(GIF 188 kb)

11356_2017_9502_MOESM1_ESM.tif (4.3 mb)
High resolution image (TIFF 4425 kb)
11356_2017_9502_Fig5_ESM.gif (386 kb)
Supplementary Fig. 2

(GIF 385 kb)

11356_2017_9502_MOESM2_ESM.tif (12.2 mb)
High resolution image (TIFF 12498 kb)
11356_2017_9502_Fig6_ESM.gif (354 kb)
Supplementary Fig. 3

(GIF 354 kb)

11356_2017_9502_MOESM3_ESM.tif (12 mb)
High resolution image (TIFF 12305 kb)
11356_2017_9502_Fig7_ESM.gif (44 kb)
Supplementary Fig. 4

(GIF 43 kb)

11356_2017_9502_MOESM4_ESM.tif (1009 kb)
High resolution image (TIFF 1008 kb)
11356_2017_9502_MOESM5_ESM.docx (18 kb)
Supplementary Table 1 (DOCX 18 kb)
11356_2017_9502_MOESM6_ESM.docx (18 kb)
Supplementary Table 2 (DOCX 18 kb)
11356_2017_9502_MOESM7_ESM.docx (15 kb)
Supplementary Table 3 (DOCX 15 kb)

References

  1. Bae S, Lim YH, Kashima S, Yorifuji T, Honda Y, Kim H, Hong YC (2015) Non-linear concentration-response relationships between ambient ozone and daily mortality. PLoS One 10:e0129423CrossRefGoogle Scholar
  2. Brunekreef B, Holgate ST (2002) Air pollution and health. Lancet 360:1233–1242CrossRefGoogle Scholar
  3. Carreras H, Zanobetti A, Koutrakis P (2015) Effect of daily temperature range on respiratory health in Argentina and its modification by impaired socio-economic conditions and PM10 exposures. Environ Pollut 206:175–182CrossRefGoogle Scholar
  4. Chan PK, Tam WW, Lee TC, Hon KL, Lee N, Chan MC, Mok HY, Wong MC, Leung TF, Lai RW, Yeung AC, Ho WC, Nelson EA, Hui DS (2015) Hospitalization incidence, mortality, and seasonality of common respiratory viruses over a period of 15 years in a developed subtropical city. Medicine 94:e2024CrossRefGoogle Scholar
  5. Chen B, Hong C, Kan H (2004) Exposures and health outcomes from outdoor air pollutants in China. Toxicology 198:291–300CrossRefGoogle Scholar
  6. Chen L, Villeneuve PJ, Rowe BH, Liu L, Stieb DM (2014) The Air Quality Health Index as a predictor of emergency department visits for ischemic stroke in Edmonton, Canada. J Expo Sci Environl Epidemiol 24:358–364CrossRefGoogle Scholar
  7. Chiusolo M, Cadum E, Stafoggia M, Galassi C, Berti G, Faustini A, Bisanti L, Vigotti MA, Dessi MP, Cernigliaro A, Mallone S, Pacelli B, Minerba S, Simonato L, Forastiere F, EpiAir Collaborative G (2011) Short-term effects of nitrogen dioxide on mortality and susceptibility factors in 10 Italian cities: the EpiAir Study. Environ Health Perspect 119:1233–1238CrossRefGoogle Scholar
  8. Dai X, He X, Zhou Z, Chen J, Wei S, Chen R, Yang B, Feng W, Shan A, Wu T, Guo H (2015) Short-term effects of air pollution on out-of-hospital cardiac arrest in Shenzhen, China. Int J Cardiol 192:56–60CrossRefGoogle Scholar
  9. Ferrari J, Shiue I, Seyfang L, Matzarakis A, Lang W, Austrian Stroke Registry C (2015) Weather as physiologically equivalent was not associated with ischemic stroke onsets in Vienna, 2004–2010. Environ Sci Pollut Res Int 22:8756–8762CrossRefGoogle Scholar
  10. Gleason JA, Fagliano JA (2015) Associations of daily pediatric asthma emergency department visits with air pollution in Newark, NJ: utilizing time-series and case-crossover study designs. J Asthma: Off J Assoc Care Asthma 52:815–822Google Scholar
  11. Lang-Yona N, Shuster-Meiseles T, Mazar Y, Yarden O, Rudich Y (2016) Impact of urban air pollution on the allergenicity of Aspergillus fumigatus conidia: outdoor exposure study supported by laboratory experiments. Sci Total Environ 541:365–371CrossRefGoogle Scholar
  12. Lee H, Honda Y, Hashizume M, Guo YL, Wu CF, Kan H, Jung K, Lim YH, Yi S, Kim H (2015) Short-term exposure to fine and coarse particles and mortality: a multicity time-series study in East Asia. Environ Pollut 207:43–51CrossRefGoogle Scholar
  13. Li H, Chen R, Meng X, Zhao Z, Cai J, Wang C, Yang C, Kan H (2015) Short-term exposure to ambient air pollution and coronary heart disease mortality in 8 Chinese cities. Int J Cardiol 197:265–270CrossRefGoogle Scholar
  14. Lin H, Zhang Y, Liu T, Xiao J, Xu Y, Xu X, Qian Z, Tong S, Luo Y, Zeng W, Ma W (2014) Mortality reduction following the air pollution control measures during the 2010 Asian Games. Atmos Environ 91:24–31CrossRefGoogle Scholar
  15. Lin H, Tao J, Du Y, Liu T, Qian Z, Tian L, Di Q, Rutherford S, Guo L, Zeng W, Xiao J, Li X, He Z, Xu Y, Ma W (2015) Particle size and chemical constituents of ambient particulate pollution associated with cardiovascular mortality in Guangzhou, China. Environ PollutGoogle Scholar
  16. Lin H, Liu T, Xiao J, Zeng W, Li X, Guo L, Zhang Y, Xu Y, Tao J, Xian H, Syberg KM, Qian ZM, Ma W (2016a) Mortality burden of ambient fine particulate air pollution in six Chinese cities: results from the Pearl River Delta Study. Environ Int 96:91–97CrossRefGoogle Scholar
  17. Lin H, Tao J, Du Y, Liu T, Qian Z, Tian L, Di Q, Rutherford S, Guo L, Zeng W, Xiao J, Li X, He Z, Xu Y, Ma W (2016b) Particle size and chemical constituents of ambient particulate pollution associated with cardiovascular mortality in Guangzhou, China. Environ Pollut 208:758–766CrossRefGoogle Scholar
  18. Liu T, Zhang YH, Xu YJ, Lin HL, Xu XJ, Luo Y, Xiao J, Zeng WL, Zhang WF, Chu C, Keogh K, Rutherford S, Qian Z, Du YD, Hu M, Ma WJ (2014) The effects of dust-haze on mortality are modified by seasons and individual characteristics in Guangzhou, China. Environ Pollut 187:116–123CrossRefGoogle Scholar
  19. Lu F, Zhou L, Xu Y, Zheng T, Guo Y, Wellenius GA, Bassig BA, Chen X, Wang H, Zheng X (2015) Short-term effects of air pollution on daily mortality and years of life lost in Nanjing, China. Sci Total Environ 536:123–129CrossRefGoogle Scholar
  20. Nasser Z, Salameh P, Nasser W, Abou Abbas L, Elias E, Leveque A (2015) Outdoor particulate matter (PM) and associated cardiovascular diseases in the Middle East. Int J Occup Med Environ Health 28:641–661CrossRefGoogle Scholar
  21. Perez L, Grize L, Infanger D, Kunzli N, Sommer H, Alt GM, Schindler C (2015) Associations of daily levels of PM10 and NO(2) with emergency hospital admissions and mortality in Switzerland: trends and missed prevention potential over the last decade. Environ Res 140:554–561CrossRefGoogle Scholar
  22. Pinheiro Sde L, Saldiva PH, Schwartz J, Zanobetti A (2014) Isolated and synergistic effects of PM10 and average temperature on cardiovascular and respiratory mortality. Rev Saude Publica 48:881–888CrossRefGoogle Scholar
  23. Rodopoulou S, Samoli E, Chalbot MC, Kavouras IG (2015) Air pollution and cardiovascular and respiratory emergency visits in Central Arkansas: a time-series analysis. Sci Total Environ 536:872–879CrossRefGoogle Scholar
  24. Samoli E, Peng R, Ramsay T, Pipikou M, Touloumi G, Dominici F, Burnett R, Cohen A, Krewski D, Samet J, Katsouyanni K (2008) Acute effects of ambient particulate matter on mortality in Europe and North America: results from the APHENA study. Environ Health Perspect 116:1480–1486CrossRefGoogle Scholar
  25. Scheers H, Jacobs L, Casas L, Nemery B, Nawrot TS (2015) Long-term exposure to particulate matter air pollution is a risk factor for stroke: meta-analytical evidence. Stroke 46:3058–3066CrossRefGoogle Scholar
  26. Shenzhen Statistics Bureau (2015) Statistics annual report in Shenzhen ChinaGoogle Scholar
  27. Shenzhen Traffic Management Bureau (2015) Transportation statistics annual report in Shenzhen, ChinaGoogle Scholar
  28. Silverman RA, Ito K (2010) Age-related association of fine particles and ozone with severe acute asthma in New York City. J Allergy Clin Immunol 125(367–373):e5Google Scholar
  29. Stafoggia M et al (2015) Desert dust outbreaks in southern Europe: contribution to daily PM concentrations and short-term associations with mortality and hospital admissions. Environ Health PerspectGoogle Scholar
  30. Tian L, Qiu H, Pun VC, Ho KF, Chan CS, Yu IT (2015) Carbon monoxide and stroke: a time series study of ambient air pollution and emergency hospitalizations. Int J Cardiol 201:4–9CrossRefGoogle Scholar
  31. Xie SH, Wu YS, Liu XJ, Fu YB, Li SS, Ma HW, Zou F, Cheng JQ (2016) Mortality from road traffic accidents in a rapidly urbanizing Chinese city: a 20-year analysis in Shenzhen, 1994–2013. Traffic Inj Prev 17:39–43CrossRefGoogle Scholar
  32. World Health Organization (2006) The international classification of diseases ICD-10, 2nd edn., vol 1Google Scholar

Copyright information

© Springer-Verlag GmbH Germany 2017

Authors and Affiliations

  • Yinsheng Guo
    • 1
    • 2
  • Yue Ma
    • 1
  • Yanwei Zhang
    • 1
  • Suli Huang
    • 1
  • Yongsheng Wu
    • 1
  • Shuyuan Yu
    • 1
  • Fei Zou
    • 2
    Email author
  • Jinquan Cheng
    • 1
    Email author
  1. 1.Shenzhen Center for Disease Control and PreventionShenzhenChina
  2. 2.Department of Occupational Health and Occupational Medicine, School of Public Health and Tropical MedicineSouthern Medical UniversityGuangzhouChina

Personalised recommendations