Environmental Science and Pollution Research

, Volume 24, Issue 13, pp 12261–12272 | Cite as

Cadmium and copper induced changes in growth, oxidative metabolism and terpenoids of Tanacetum parthenium

  • Mostafa Hojati
  • Seyed Ali Mohammad Modarres-SanavyEmail author
  • Sattar Tahmasebi Enferadi
  • Mohammad Majdi
  • Faezeh Ghanati
  • Soudeh Farzadfar
  • Alireza Pazoki
Research Article


Morphological and biochemical responses of feverfew plants exposed to low (5 μM) and high (35 and 70 μM) levels of Cd or Cu were investigated. Increasing metal supply notably reduced the plant biomass. Elevated Cd and Cu levels also resulted in an increase in the leaf proline content. Besides, decrease in ascorbic acid (AsA) and glutathione (GSH) contents was similar in the leaves of Cd- and Cu-treated plants, indicating altered biosynthesis of AsA and GSH under metal excess. High metal doses stimulated increase in antioxidative enzyme activities that could be related to elevated hydrogen peroxide (H2O2) content and subsequent lipid peroxidation. Cd was typically more accumulated in shoots and roots than Cu, leading to higher translocation factor at high Cd doses. In terms of essential oil content, it seems that Cd had an inhibitory effect during the experiment, whereas Cu was found to stimulate it only at 5 μM. Furthermore, high Cd supply enhanced the relative proportion of monoterpene hydrocarbons, while Cu increased the proportion of sesquiterpenes, especially at 5 μM. This result provides the first evidence of the response of feverfew plants to Cd or Cu by associating stress-related responses with changes in terpenoids.


Bioaccumulation Heavy metals Feverfew Oxidative stress Terpenoids 



This work was financially supported by Tarbiat Modares University.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

11356_2017_8846_MOESM1_ESM.docx (346 kb)
ESM 1 (DOCX 345 kb)


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Copyright information

© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  • Mostafa Hojati
    • 1
  • Seyed Ali Mohammad Modarres-Sanavy
    • 1
    Email author
  • Sattar Tahmasebi Enferadi
    • 2
  • Mohammad Majdi
    • 3
  • Faezeh Ghanati
    • 4
  • Soudeh Farzadfar
    • 4
  • Alireza Pazoki
    • 5
  1. 1.Department of Agronomy, Faculty of AgricultureTarbiat Modares UniversityTehranIran
  2. 2.National Institute of Genetic Engineering and Biotechnology (NIGEB)TehranIran
  3. 3.Agricultural Biotechnology Department, Faculty of AgricultureUniversity of KurdistanSanandajIran
  4. 4.Department of Plant Biology, Faculty of Biological ScienceTarbiat Modares UniversityTehranIran
  5. 5.Department of Agronomy and Plant Breeding, Shahr-e-Rey BranchIslamic Azad UniversityTehranIran

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