Occurrence of endocrine disrupters and selected pharmaceuticals in Aisonas River (Greece) and environmental risk assessment using hazard indexes
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The presence of four phenolic endocrine disrupting compounds (EDCs: nonylphenol [NP], NP monoethoxylate[NP1EO], bisphenol A [BPA], triclosan, [TCS]) and four nonsteroidal anti-inflammatory drugs (NSAIDs: ibuprofen[IBF], ketoprofen [KFN], naproxen [NPX], diclofenac [DCF]) in a Greek river receiving treated municipal wastewater was investigated in this study.
Samples were taken from four different points of the river and from the outlet of a sewage treatment plant (STP) during six sampling campaigns, and they were analyzed using gas chromatography–mass spectrometry.
According to the results, EDCs were detected in almost all samples, whereas NSAIDs were detected mainly in wastewater and in the part of the river that receives wastewater from the STP. Among the target compounds, the highest mean concentrations in the river were detected for NP (1,345 ng L−1) and DCF (432 ng L−1). Calculation of daily loads of the target compounds showed that STP seems to be the major source of NSAIDs to the river, whereas other sources contribute significantly to the occurrence of EDCs. The environmental risk due to the presence of target compounds in river water was estimated, calculating risk quotients for different aquatic organisms (algae, daphnids, and fish). Results denoted the possible threat for the aquatic environment due to the presence of NP and TCS in the river.
KeywordsEmerging contaminants Surface waters Wastewater Risk assessment
- APHA (1998) Standard methods for the examination of water and wastewater, 20th ed. American Public Health Association, Port City Press, Baltimore, Maryland, USAGoogle Scholar
- Birkett JW, Lester JN (2003) Endocrine disrupters in wastewater and sludge treatment processes, CRC Press LLCGoogle Scholar
- Brooke LT (1993) Acute and chronic toxicity of nonylphenol to ten species of aquatic organisms. USEPA Draft Report, EPA Contract No 68-C1-0034Google Scholar
- European Union (2001) Decision No 2455/2001/EC of the European Parliament and of the council of 20 November 2001 establishing the list of priority substances in the field of water policy and amending directive 2000/60/EC, Off. J. L331, 15/12/2001Google Scholar
- European Union (2003) Technical Guidance Document on Risk Assessment (Part II), European Chemicals BureauGoogle Scholar
- European Union (2006) Proposal for a Directive of the European Parliament and of the Council on environmental quality standards in the field of water policy and amending Directive 2000/60/EC, 2006/0129, Brussels, 17.7.2006Google Scholar
- Ferrari B, Mons R, Vollat B, Fraysse B, Paxeus N, Lo Gindice R, Pollio A, Garric J (2004) Environmental risk assessment of six human pharmaceuticals: Are the current environmental risk assessment procedures sufficient for the protection of the aquatic environment? Environ Tox Chem 23:1344–1354CrossRefGoogle Scholar
- Kopf W (1997) Wirkung endokriner stoffe in biotests mit wasserogranismen. In Stoffe mit endokriner wirkung in wasser. Bayerisches landesamt fur wasserwitschaft, Institut fur Wasserforschung Munchen (ed) OldenbourgGoogle Scholar
- Möder M, Braun P, Lange F, Schrader S, Lorenz W (2007) Determination of endocrine disrupting compounds and acidic drugs in water by coupling of derivatization, gas chromatography and negative-chemical ionization mass spectrometry. Clean 35:444–451Google Scholar
- Nassef M, Matsumoto S, Seki M, Kang IJ, Moroishi J, Shimasaki Y, Oshima Y (2009) Pharmaceuticals and personal care products toxicity to Japanese medaka fish (Oryzias latipes). J Fac Agr Kyushu U 54:407–411Google Scholar
- Samaras VG, Thomaidis NS, Stasinakis AS, Lekkas TD (2011) An analytical method for the simultaneous trace determination of acidic pharmaceuticals and phenolic endocrine disrupting chemicals in wastewater and sewage sludge by gas chromatography–mass spectrometry. Anal Bioanal Chem 399:2549–2561CrossRefGoogle Scholar
- Stephenson RR (1983) Diphenylol propane: acute toxicity to Daphna magna and Selenastrum capricornutum. Shell group research report SBGR.83.216Google Scholar