Background, aim, and scope
This study developed an integrated approach to identify pollutant sources of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) of workers based on their blood contents.
Materials and methods
We first measured blood PCDD/F contents of sinter plant workers and residents living near the plant. By comparing those blood indicatory PCDD/Fs found for residents with those for sinter plant workers, exposure-related blood indicatory PCDD/Fs were identified for each selected worker. We then measured PCDD/F concentrations of four different sinter plant workplaces and three different ambient environments of the background. By comparing those airborne indicatory PCDD/Fs found for ambient environments with those for sinter plant workplaces, exposure-related airborne indicatory PCDD/Fs for each workplace were obtained. Finally, by matching exposure-related blood indicatory PCDD/Fs with exposure-related airborne indicatory PCDD/Fs, all suspected pollutant sources were identified for each selected worker.
Poor Pearson correlations were found between workers’ blood contents and their corresponding PCDD/F exposures. Significant differences were found in the top three blood indicatory PCDD/Fs among the selected workers. By matching exposure-related blood indicatory PCDD/Fs with exposure-related airborne indicatory PCDD/Fs, two to three suspected pollutant sources were identified for each selected worker.
The poor Pearson correlation found between workers’ airborne PCDD/Fs exposures and their blood contents was because workers’ blood PCDD/Fs contents were contributed not only by workers’ occupational exposures, but also by other exposure sources and exposure routes. The difference in blood indicatory PCDD/Fs among the selected workers were obviously due to the intrinsic differences in their time/activity patterns in the involved workplaces. While workers used a dust respirator to perform their jobs, gas phase exposure-related airborne indicatory PCDD/Fs played an important role on identifying suspected pollutant sources. But if a dust respirator was not used, the gas + particle phase exposure-related airborne indicatory PCDD/Fs would become the key factor for identifying suspected pollutant sources.
The developed integrated approach could identify all suspected pollutant sources effectively for selected workers based on their blood contents. The identified pollutant sources were theoretically plausible since they could be verified by examining workers’ time/activity patterns, their status in using dust respirators, and the concentrations of PCDD/Fs found in the selected workplace atmospheres.
Recommendations and perspectives
The developed technique can be used to identify possible pollutant sources not only for workers but also for many other exposure groups associated with various emission sources and exposure routes in the future.
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Agramunt MC, Schuhmacher M, Hernandez JM, Domingo JL (2005) Levels of dioxins and furans in plasma of nonoccupationally exposed subjects living near a hazardous waste incinerator. J Expo Anal Environ Epidemiol 15:29–34
Alcock RE, Gemmill R, Jones KC (1999) Improvements to the UK PCDD/F and PCB atmospheric emission inventory following an emissions measurement programme. Chemosphere 38:759–770
Anderson DR, Fisher R (2002) Sources of dioxins in the United Kingdom: the steel industry and other sources. Chemosphere 46:371–381
Aries E, Anderson DR, Fisher R, Fray TAT, Hemfrey D (2006) PCDD/F and "Dioxin-like" PCB emissions from iron ore sintering plants in the UK. Chemosphere 65:1470–1480
Chen HL, Liao PC, Su HJ, Guo YL, Chen CH, Lee CC (2005) Profile of PCDD/F levels in serum of general Taiwanese between different gender, age and smoking status. Sci Total Environ 337:31–43
Chen HL, Shih TS, Huang PC, Hsieh CY, Lee CC (2006) Exposure of arc-furnace-plant workers to polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs). Chemosphere 64:666–671
Cohen J, Cohen P, West SG, Aiken LS (2003) Applied multiple regression/correlation analysis for the behavioral sciences, 3rd edn. Erlbaum, Hillsdale, NJ
Hu SW, ChangChien GP, Chan CC (2004) PCDD/Fs levels in indoor environments and blood of workers of three municipal waste incinerators in Taiwan. Chemosphere 55:611–620
Kim BH, Ikonomou MG, Lee SJ, Kim HS, Chang YS (2005) Concentrations of polybrominated diphenyl ethers, polychlorinated dibenzo-p-dioxins and dibenzofurans, and polychlorinated biphenyls in human blood samples from Korea. Sci Total Environ 336:45–56
Kiviranta H, Tuomisto JT, Tuomisto J, Tukiainen E, Vartiainen T (2005) Polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls in the general population in Finland. Chemosphere 60:854–869
Kumagai S, Koda S, Miyakita T, Ueno M (2002) Polychlorinated dibenzo-p-dioxin and dibenzofuran concentrations in serum samples of workers at intermittently burning municipal waste incinerators in Japan. Occup Environ Med 59:362–368
Lee WS, ChangChien GP, Wang LC, Lee WJ, Tsai PJ, Wu KY, Lin C (2004) Source identification of PCDD/Fs for various atmospheric environments in a highly industrialized city. Environ Sci Technol 38:4937–4944
Oh JE, Choi SD, Lee SJ, Chang YS (2006) Influence of a municipal solid waste incinerator on ambient air and soil PCDD/Fs levels. Chemosphere 64:579–587
Olie K, Vermeulen PL, Hutzinger O (1977) Chlorodibenzo-p-dioxins and chlorodibenzofurans are trace components of fly ash and flue gas of some municipal incinerators in The Netherlands. Chemosphere 6:455–459
Park H, Ikonomou MG, Kim HS, Choi JW, Chang YS (2009) Dioxin and dioxin-like PCB profiles in the serum of industrial and municipal waste incinerator workers in Korea. Environ Int 35:580–587
Schecter A, Papke O, Ball M, Lis A, Brandt-Rauf P (1995) Dioxin concentrations in the blood of workers at municipal waste incinerators. Occup Environ Med 52:385–387
Schuhmacher M, Domingo JL, Llobet JM, Lindstrom G, Wingfors H (1999) Dioxin and dibenzofuran concentrations in blood of a general population from Tarragona, Spain. Chemosphere 38:1123–1133
Shih M, Lee WJ, Shih TS, Huang SL, ChangChien GP, Wang LC, Tsai PJ (2006a) Characterization of dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) in the atmosphere of different workplaces of a sinter plant. Sci Total Environ 366:197–205
Shih TS, Chen HL, Wu YL, Lin YC, Lee CC (2006b) Exposure assessment of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) in temporary municipal-waste-incinerator maintenance workers before and after annual maintenance. Chemosphere 64:1444–1449
Tepper A, Burt S, Piacitelli L, Patterson JDG (1997) Serum levels of polychlorinated dibenzo-p-dioxins and dibenzofurans in pulp and paper mill workers. Chemosphere 34:1587–1603
USEPA (United States Environmental Protection Agency) (1994) Method 1613: Tetra-Through Octa-Chlorinated Dioxins and Furans by Isotope Dilution HRGC/HRM; Revision B. EPA 821/B-94-005.
Yang HH, Lee WJ, Chen SJ, Lai SO (1998) PAH emission from various industrial stacks. J Hazard Mater 60:159–174
We are grateful to the Institute of Occupational Safety and Health (IOSH) in Taiwan for supporting this research project. The co-author, Lin-Chi Wang, has the equal contribution to this paper as the corresponding author.
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Chen, Y., Tsai, P., Wang, L. et al. An integrated approach for identification of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) pollutant sources based on human blood contents. Environ Sci Pollut Res 17, 759–769 (2010). https://doi.org/10.1007/s11356-009-0162-0
- Ambient environments
- Blood PCDD/Fs
- Indicatory analysis
- Sinter plant workers
- Source identification