Advertisement

Is there an association between sleep bruxism and obstructive sleep apnea syndrome? A systematic review

  • Ana Júlia da Costa Lopes
  • Thays Crosara Abrahão Cunha
  • Maria Cecília Magalhães Monteiro
  • Júnia Maria Serra-Negra
  • Luana Cardoso Cabral
  • Paulo Cézar Simamoto JúniorEmail author
Sleep Breathing Physiology and Disorders • Original Article

Abstract

Purpose

To elucidate current knowledge on the potential association and causality between sleep bruxism (SB) and obstructive sleep apnea (OSA) using full-night polysomnography.

Methods

Search strategies were developed for PubMed, Web of Science, Cochrane, LILACS, MEDLINE, and BBO-ODO and conducted until May 2019. The methodological quality was evaluated using the Qu-ATEBS tool.

Results

Two hundred seventy articles were identified and after independent screening of abstracts by two authors, 17 articles underwent full-text reading. Ten articles were excluded for not meeting the inclusion criteria and 7 were included in qualitative synthesis. Four studies support the association between SB and OSA: (a) a subtype of OSA patients may have SB as a protective response to respiratory events, (b) most episodes of bruxism occur shortly after the end of apnea/hypopnea (AH) events, (c) bruxism episodes occur secondary to arousals arising from AH events, and (d) there is a correlation between the frequency of SB and AH events, and three studies did not support: (e) AH episodes are related to non-specific SB oromotor activities, (f) SB episodes are not directly associated with the end of AH events, and (g) patients with OSA did not experience more SB events than control group.

Conclusion

There is no scientific evidence to support a conclusive relationship between SB and OSA. Further, well-designed and randomized studies with control groups are needed to investigate whether possible mechanisms common to SB and OSA exist and whether OSA treatment could improve SB negative oral health outcomes in patients with SB and comorbidity of OSA.

Keywords

Bruxism Obstructive sleep apnea Sleep bruxism Sleep-disordered breathing Systematic review 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Supplementary material

11325_2019_1919_MOESM1_ESM.pdf (314 kb)
ESM 1 (PDF 313 kb)

References

  1. 1.
    American Academy of Sleep Medicine (ed) (2014) International Classification of Sleep Disorders, 3rd edn. Darien, American Academy of Sleep MedicineGoogle Scholar
  2. 2.
    Lobbezoo F, Ahlberg J, Glaros AG, Kato T, Koyano K, Lavigne GJ, de Leeuw R, Manfredini D, Svensson P, Winocur E (2013) Bruxism defined and graded: an international consensus. J Oral Rehabil 40:2–4CrossRefGoogle Scholar
  3. 3.
    Klasser GD, Rei N, Lavigne GJ (2015) Sleep bruxism etiology: the evolution of a changing paradigm. J Can Dent Assoc 81:f2PubMedGoogle Scholar
  4. 4.
    Lobbezoo F, Ahlberg J, Raphael KG, Wetselaar P, Glaros AG, Kato T, Santiago V, Winocur E, de Laat A, de Leeuw R, Koyano K, Lavigne GJ, Svensson P, Manfredini D (2018) International consensus on the assessment of bruxism: report of a work in progress. J Oral Rehabil 45(11):837–844.  https://doi.org/10.1111/joor.12663 CrossRefPubMedPubMedCentralGoogle Scholar
  5. 5.
    De Luca CG, Singh V, Gozal D, Major PW, Flores-Mir C (2014) Sleep bruxism and sleep-disordered breathing: a systematic review. J Oral & Facial Pain and headache 28(4):299–305.  https://doi.org/10.11607/ofph.1294 CrossRefGoogle Scholar
  6. 6.
    Castroflorio T, Bargellini A, Rossini G, Cugliari G, Rainoldi A, Deregibus A (2015) Risk factors related to sleep bruxism in children: a systematic literature review. Arch Oral Biol 60(11):1618–1624.  https://doi.org/10.1016/j.archoralbio.2015.08.014 CrossRefPubMedGoogle Scholar
  7. 7.
    Stuginski-Barbosa J, Porporatti AL, Costa YM, Svensson P, Conti PC (2017) Agreement of the International Classification of Sleep Disorders Criteria with polysomnography for sleep bruxism diagnosis: a preliminary study. J Prosthet Dent 117(1):61–66.  https://doi.org/10.1016/j.prosdent.2016.01.035 CrossRefPubMedGoogle Scholar
  8. 8.
    American Academy of Sleep Medicine (2005). International classification of sleep disorders, 2nd ed.: Diagnostic and coding manual. Westchester, IL: American Academy of Sleep MedicineGoogle Scholar
  9. 9.
    Kim ST, Choi JH, Jeon HG, Cha HE, Kim DY, Chung YS (2004) Polysomnographic effects of nasal surgery for snoring and obstructive sleep apnea. Acta Otolaryngol 124(3):297–300CrossRefGoogle Scholar
  10. 10.
    Udwadia ZF, Doshi AV, Lonkar SG, Singh CI (2004) Prevalence of sleep-disordered breathing and sleep apnea in middle-aged urban Indian men. Am J Respir Crit Care Med 169(2):168–173CrossRefGoogle Scholar
  11. 11.
    Kato T, Rompre P, Montplaisir JY, Sessle BJ, Lavigne GJ (2001) Sleep bruxism: an oromotor activity secondary to microarousal. J Dent Res 80:1940–1944CrossRefGoogle Scholar
  12. 12.
    Huynh NT, Guilleminault C (2009) Sleep bruxism in children. In: Lavigne GJ, Cistulli PA, Smith MT (eds) Sleep medicine for dentists. A practical overview, Chicago, Quintessence Co, pp 125–131Google Scholar
  13. 13.
    Lavigne G, Manzini C, Huynh NT et al (2011) Sleep bruxism. In: Kryger MH, Roth T, Dement WC (eds) Principles and practice of sleep medicine, 5th edn. Elsevier Saunders, St Louis, pp 1129–1139Google Scholar
  14. 14.
    Carra MC, Huynh N, Fleury B, Lavigne G (2015) Overview on sleep bruxism for sleep medicine clinicians. Sleep Med Clin 10(3):375–384.  https://doi.org/10.1016/j.jsmc.2015.05.005 CrossRefPubMedGoogle Scholar
  15. 15.
    Senaratna CV, Perret JL, Lodge CJ, Lowe AJ, Campbell BE, Matheson MC, Hamilton GS, Dharmage SC (2016) Prevalence of obstructive sleep apnea in the general population: a systematic review. Sleep Med Rev 34:70–81.  https://doi.org/10.1016/j.smrv.2016.07.002 CrossRefPubMedGoogle Scholar
  16. 16.
    Kostrzewa-Janicka J, Jurkowski P, Zycinska K, Przybyłowska D, Mierzwinska-Nastalska E (2015) Sleep-related breathing disorders and bruxism. Adv Exp Med Biol 873:9–14CrossRefGoogle Scholar
  17. 17.
    Leger D, Bayon V, Laaban J, Philip P (2012) Impact of sleep apnea on economics. Sleep Med Rev 16:455–462CrossRefGoogle Scholar
  18. 18.
    Lavigne GJ, Rompre PH, Montplaisir JY (1996) Sleep bruxism: validity of clinical research diagnostic criteria in a controlled polysomnographic study. J Dent Res 75:546–552CrossRefGoogle Scholar
  19. 19.
    Maluly M, Andersen ML, Dal-Fabbro C, Garbuio S, Bittencourt L, de Siqueira JT et al (2013) Polysomnographic study of the prevalence of sleep bruxism in a population sample. J Dent Res 92(7l):97–103CrossRefGoogle Scholar
  20. 20.
    Serra-Negra JM, Paiva SM, Auad SM, Ramos-Jorge ML, Pordeus IA (2012) Signs, symptoms, parafunctions and associated factors of parent-reported sleep bruxism in children: a case-control study. Braz Dent J 23(6):746–752CrossRefGoogle Scholar
  21. 21.
    Paesani DA, Lobbezoo F, Gelos C, Guarda-Nardini L, Ahlberg J, Manfredini D (2013) Correlation between self-reported and clinically based diagnoses of bruxism in temporomandibular disorders patients. J Oral Rehabil 40(11):803–809.  https://doi.org/10.1111/joor.12101 CrossRefPubMedGoogle Scholar
  22. 22.
    Lam MH, Zhang J, Li AM, Wing YK (2011) A community study of sleep bruxism in Hong Kong children: association with comorbid sleep disorders and neurobehavioral consequences. Sleep Med 12:641–645CrossRefGoogle Scholar
  23. 23.
    Insana SP, Gozal D, Mcneil DW, Montgomery Downs HE (2014) Community based study of sleep bruxism during early childhood. Sleep Med 14:183–188CrossRefGoogle Scholar
  24. 24.
    Tachibana M, Kato T, Kato-Nishimura K, Matsuzawa S, Mohril I, Taniike M (2016) Associations of sleep bruxism with age, sleep apnea, and daytime problematic behaviors in children. Oral Dis 22(6):557–565CrossRefGoogle Scholar
  25. 25.
    Ohayon MM, Li KK, Guilleminault C (2001) Risk factors for sleep bruxism in the general population. Chest 119:53–61CrossRefGoogle Scholar
  26. 26.
    Kato T, Velly AM, Nakane T, Masuda Y, Maki S (2012) Age is associated with self-reported sleep bruxism, independently of tooth loss. Sleep Breath 16:1159–1165CrossRefGoogle Scholar
  27. 27.
    DiFrancesco RC, Junqueira PA, Trezza PM, de Faria ME, Frizzarini R, Zerati FE (2004) Improvement of bruxism after T & A surgery. Int J Pediatr Otorhinolaryngol 68(4):441–445CrossRefGoogle Scholar
  28. 28.
    Hosoya H, Kitaura H, Hashimoto T, Ito M, Kinbara M, Deguchi T, Irokawa T, Ohisa N, Ogawa H, Takano-Yamamoto T (2014) Relationship between sleep bruxism and sleep respiratory events in patients with obstructive sleep apnea syndrome. Sleep Breath 18(4):837–844.  https://doi.org/10.1007/s11325-014-0953-5 CrossRefPubMedGoogle Scholar
  29. 29.
    Ferreira NMR, Santos JFF, Santos MBF, Marchini L (2015) Sleep bruxism associated with obstructive sleep apnea syndrome in children. J Cranio 33(4):251–255.  https://doi.org/10.1080/08869634.2015 CrossRefGoogle Scholar
  30. 30.
    Kato T, Katase T, Yamashita S, Sugita H, Muraki H, Mikami A, Okura M, Ohi M, Masuda Y, Taniguchi M (2013) Responsiveness of jaw motor activation to arousals during sleep in patients with obstructive sleep apnea syndrome. J Clin Sleep Med 9(8):759–765PubMedPubMedCentralGoogle Scholar
  31. 31.
    Khoury S, Rouleau GA, Rompre PH, Mayer P, Montplaisir JY, Lavigne GJ (2008) A significant increase in breathing amplitude precedes sleep bruxism. Chest. 134:332–337CrossRefGoogle Scholar
  32. 32.
    Manfredini D, Guarda-Nardini L, Marchese-Ragona R, Lobbezoo F (2015) Theories on possible temporal relationships between sleep bruxism and obstructive sleep apnea events. An expert opinion. Sleep Breath 19(4):1459–1465.  https://doi.org/10.1007/s11325-015-1163-5 CrossRefPubMedGoogle Scholar
  33. 33.
    Jokubauskas L, Baltrušaitytė A (2017) Relationship between obstructive sleep apnoea syndrome and sleep bruxism: a systematic review. J Oral Rehabil 44(2):144–153.  https://doi.org/10.1111/joor.12468 CrossRefPubMedGoogle Scholar
  34. 34.
    Dawson A, Raphael KG, Glaros A, Axelsson S, Arima T, Ernberg M, Farella M, Lobbezoo F, Manfredini D, Michelotti A, Svensson P, List T (2013) Development of a quality-assessment tool for experimental bruxism studies: reliability and validity. J Orofac Pain 27:111–122CrossRefGoogle Scholar
  35. 35.
    Phillips BA, Okeson J, Paesani D, Gilmore R (1986) Effect of sleep position on sleep apnea and parafunctional activity. Chest. 90(3):424–429CrossRefGoogle Scholar
  36. 36.
    Okeson JP, Phillips BA, Berry DT, Cook YR, Cabelka JF (1991) Nocturnal bruxing events in subjects with sleep-disordered breathing and control subjects. J Craniomandib Disord 5(4):258–264PubMedGoogle Scholar
  37. 37.
    Sjöholm TT, Lowe AA, Miyamoto K, Fleetham JA, Ryan CF (2000) Sleep bruxism in patients with sleep-disordered breathing. Arch Oral Biol 45(10):889–896CrossRefGoogle Scholar
  38. 38.
    Saito M, Yamaguchi T, Mikami S, Watanabe K, Gotouda A, Okada K, Hishikawa R, Shibuya E, Lavigne G (2014) Temporal association between sleep apnea-hypopnea and sleep bruxism events. J Sleep Res 23:196–203.  https://doi.org/10.1111/jsr.12099 CrossRefGoogle Scholar
  39. 39.
    Saito M, Yamaguchi T, Mikami S, Watanabe K, Gotouda A, Okada K, Hishikawa R, Shibuya E, Shibuya Y, Lavigne G (2016) Weak association between sleep bruxism and obstructive sleep apnea. A sleep laboratory study. Sleep Breath 20:703–709.  https://doi.org/10.1007/s11325-015-1284-x CrossRefPubMedGoogle Scholar
  40. 40.
    Tan MWY, Yap AU, Chua AP, Wong JCM, Parot MVJ, Tan KBC (2018) Prevalence of sleep bruxism and its association with obstructive sleep apnea in adult patients: a retrospective polysomnographic investigation. J Oral Facial Pain Headache.  https://doi.org/10.11607/ofph.2018
  41. 41.
    Huynh N, Kato T, Rompre PH, Okura K, Saber M, Lanfranchi PA et al (2006) Sleep bruxism is associated to micro-arousals and an increase in cardiac sympathetic activity. J Sleep Res 15(3):339–346CrossRefGoogle Scholar
  42. 42.
    Lavigne GJ, Huynh N, Kato T, Okura K, Adachi K, Yao D, Sessle B (2007). Genesis of sleep bruxism: motor and autonomic-cardiac interactions. Arch Oral Biol 2007; 52(4):381–384CrossRefGoogle Scholar
  43. 43.
    Carra MC, Rompré PH, Kato T, Parrino L, Terzano MG, Lavigne GJ, Macaluso GM (2011) Sleep bruxism and sleep arousal: an experimental challenge to assess the role of cyclic alternating pattern. J Oral Rehabil 38(9):635–642.  https://doi.org/10.1111/j.1365-2842.2011.02203 CrossRefPubMedGoogle Scholar
  44. 44.
    Landry-Schönbeck A, de Grandmont P, Rompré PH, Lavigne GJ (2009) Effect of an adjustable mandibular advancement appliance on sleep bruxism: a crossover sleep laboratory study. Int J Prosthodont 22(3):251–259PubMedGoogle Scholar
  45. 45.
    Gregório PB, Athanazio RA, Bitencourt AG, Neves FB, Terse R, Hora F (2008) Symptoms of obstructive sleep apnea-hypopnea syndrome in children. J Bras Pneumol 34(6):356–361CrossRefGoogle Scholar
  46. 46.
    Franco L, Rompre PH, de Grandmont P, Abe S, Lavigne GJ (2011) A mandibular advancement appliance reduces pain and rhythmic masticatory muscle activity in patients with morning headache. J Orofac Pain 25(3):240–249PubMedGoogle Scholar
  47. 47.
    Carra MC, Huynh N, Morton P, Rompré PH, Papadakis A, Remise C, Lavigne GJ (2011) Prevalence and risk factors of sleep bruxism and wake-time tooth clenching in a 7- to 17-yr-old population. Eur J Oral Sci 119(5):386–394.  https://doi.org/10.1111/j.1600-0722.2011.00846.x CrossRefPubMedGoogle Scholar
  48. 48.
    Hesselbacher S, Subramanian S, Rao S, Casturi L, Surani S (2014) Self-reported sleep bruxism and nocturnal gastroesophageal reflux disease in patients with obstructive sleep apnea: relationship to gender and ethnicity. Open Respir Med J 8:34–40.  https://doi.org/10.2174/1874306401408010034 CrossRefPubMedPubMedCentralGoogle Scholar
  49. 49.
    Sjöholm T, Lehtinen II, Helenius H (1995) Masseter muscle activity in diagnosed sleep bruxists compared with non-symptomatic controls. J Sleep Res 4(1):48–55CrossRefGoogle Scholar
  50. 50.
    Schames SE, Schames J, Schames M, Chagall-Gundur SS (2012) Sleep bruxism, an autonomic self-regulating response by triggering the trigeminal cardiac reflex. J Calif Dent Assoc 40:670–676PubMedGoogle Scholar
  51. 51.
    Carra MC, Macaluso GM, Romprè PH, Huynh N, Parrino L, Terzano MG, Lavigne GJ (2010) Clonidine has a paradoxical effect on cyclic arousal and sleep bruxism during nREM sleep. Sleep 33:1711–1716CrossRefGoogle Scholar
  52. 52.
    Trotti LM (2017) Restless legs syndrome and sleep-related movement disorders. Sleep Neurology 4:1005–1006.  https://doi.org/10.1212/CON.0000000000000488 CrossRefGoogle Scholar
  53. 53.
    Durán-Cantolla J, Alkhraisat MH, Martínez-Null C, Aguirre JJ, Guinea ER, Anitua E (2015) Frequency of obstructive sleep apnea syndrome in dental patients with tooth wear. J Clin Sleep Med 11(4):445–450.  https://doi.org/10.5664/jcsm.4602 CrossRefPubMedPubMedCentralGoogle Scholar
  54. 54.
    Bellerive A, Montpetit A, El-Khatib H, Carra MC, Remise C, Desplats E, Huynh N (2015) The effect of rapid palatal expansion on sleep bruxism in children. Sleep Breath 19(4):1265–1271.  https://doi.org/10.1007/s11325-015-1156-4 CrossRefPubMedGoogle Scholar
  55. 55.
    Dumais IE, Lavigne GJ, Carra MC, Rompre PH, Huynh NT (2015) Could transient hypoxia be associated with rhythmic masticatory muscle activity in sleep bruxism in the absence of sleep-disordered breathing? A preliminary report. J Oral Rehabil 42:810–818CrossRefGoogle Scholar
  56. 56.
    Tsujisaka A, Haraki S, Nonoue S, Mikami A, Adachi H, Mizumori T, Yatani H, Yoshida A, Kato T (2018) The occurrence of respiratory events in young subjects with a frequent rhythmic masticatory muscle activity: a pilot study. J Prosthodont Res 62(3):317–323.  https://doi.org/10.1016/j.jpor.2017.12.004 CrossRefPubMedGoogle Scholar
  57. 57.
    Lavigne GJ, Kato T, Kolta A, Sessle BJ (2003) Neurobiological mechanisms involved in sleep bruxism. Crit Rev Oral Biol Med 14:30–46CrossRefGoogle Scholar
  58. 58.
    Lavigne G, Khoury S, Abe S, Yamaguchi T, Raphael K (2008) Bruxism physiology and pathology: an overview for clinicians. J Oral Rehabil 35(7):476–494CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Ana Júlia da Costa Lopes
    • 1
  • Thays Crosara Abrahão Cunha
    • 1
  • Maria Cecília Magalhães Monteiro
    • 1
  • Júnia Maria Serra-Negra
    • 2
  • Luana Cardoso Cabral
    • 1
  • Paulo Cézar Simamoto Júnior
    • 3
    • 4
    Email author
  1. 1.School of DentistryFederal University of Uberlandia-UFUUberlândiaBrazil
  2. 2.School of Dentistry, Department of Pediatric Dentistry and OrthodonticsFederal University of Minas Gerais-UFMGBelo HorizonteBrazil
  3. 3.School of Dentistry, Department of Occlusion, Fixed Prosthesis and Dental MaterialsFederal University of Uberlandia-UFUUberlândiaBrazil
  4. 4.Faculdade de Odontologia da Universidade Federal de Uberlândia-FOUFUUberlândiaBrazil

Personalised recommendations