Advertisement

Role of CD3+γδ-T cells in the association of obstructive sleep-disordered breathing and cancer

  • Richard Staats
  • Raquel Rodrigues
  • André Barros
  • Leonor Bacelar-Nicolau
  • Margarida Aguiar
  • Dina Fernandes
  • Susana Moreira
  • André Simões
  • Bruno Silva-Santos
  • João Valença Rodrigues
  • Cristina Barbara
  • António Bugalho de Almeida
  • Luís F. Ferreira MoitaEmail author
Sleep Breathing Physiology and Disorders • Letter to the Editors (Invited)

Notes

References

  1. 1.
    Palamaner Subash Shantha G, Kumar AA, Cheskin LJ, Pancholy SB (2015) Association between sleep-disordered breathing, obstructive sleep apnea, and cancer incidence: a systematic review and meta-analysis. Sleep Med 16:1289–1294.  https://doi.org/10.1016/j.sleep.2015.04.014 CrossRefGoogle Scholar
  2. 2.
    Sillah A, Watson NF, Schwartz SM, Gozal D, Phipps AI (2018) Sleep apnea and subsequent cancer incidence. Cancer Causes Control 29:987–994.  https://doi.org/10.1007/s10552-018-1073-5 CrossRefGoogle Scholar
  3. 3.
    Pérez-Warnisher MT, Cabezas E, Troncoso MF, Gómez T, Melchor R, Pinillos EJ, el Hachem A, Gotera C, Rodriguez P, Mahíllo I, González-Mangado N, Peces-Barba G, Seijo LM (2019) Sleep disordered breathing and nocturnal hypoxemia are very prevalent in a lung cancer screening population and may condition lung cancer screening findings: results of the prospective Sleep Apnea In Lung Cancer Screening (SAILS) study. Sleep Med 54:181–186.  https://doi.org/10.1016/j.sleep.2018.10.020 CrossRefGoogle Scholar
  4. 4.
    Koo DL, Lee S, Im JP et al (2016) Obstructive sleep apnea is associated with an increased risk of colorectal neoplasia. Gastrointest Endosc 85:568–573.e1.  https://doi.org/10.1016/j.gie.2016.07.061 Google Scholar
  5. 5.
    Tanday S (2016) Severe sleep apnoea linked to melanoma risk. Lancet Oncol 17:e229.  https://doi.org/10.1016/s1470-2045(16)30161-9 CrossRefGoogle Scholar
  6. 6.
    Fang HF, Miao NF, Chen CD, Sithole T, Chung MH (2015) Risk of cancer in patients with insomnia, parasomnia, and obstructive sleep apnea: a nationwide nested case-control study. J Cancer 6:1140–1147.  https://doi.org/10.7150/jca.12490 CrossRefGoogle Scholar
  7. 7.
    Cao J, Feng J, Li L, Chen B (2015) Obstructive sleep apnea promotes cancer development and progression: a concise review. Sleep Breath 19:453–457.  https://doi.org/10.1007/s11325-015-1126-x CrossRefGoogle Scholar
  8. 8.
    Kendzerska T, Leung RS, Hawker G, Tomlinson G, Gershon AS (2014) Obstructive sleep apnea and the prevalence and incidence of cancer. Cmaj 186:985–992.  https://doi.org/10.1503/cmaj.140238 CrossRefGoogle Scholar
  9. 9.
    Iwakura Y, Wakita D, Nishikawa H et al (2010) Tumor-infiltrating IL-17-producing γδ T cells support the progression of tumor by promoting angiogenesis. Eur J Immunol 40:1927–1937.  https://doi.org/10.1002/eji.200940157 CrossRefGoogle Scholar
  10. 10.
    Rei M, Pennington DJ, Silva-Santos B (2015) The emerging protumor role of γδ T lymphocytes: implications for cancer immunotherapy. Cancer Res 75:798–802.  https://doi.org/10.1158/0008-5472.CAN-14-3228 CrossRefGoogle Scholar
  11. 11.
    Malissen M, Serre K, Silva-Santos B et al (2018) Tumor-associated neutrophils suppress pro-tumoral IL-17+ γδ T cells through induction of oxidative stress. PLoS Biol 16:e2004990.  https://doi.org/10.1371/journal.pbio.2004990 CrossRefGoogle Scholar
  12. 12.
    Silva-Santos B, Serre K, Norell H (2012) γδ T cells in cancer. Nat Rev Immunol:23–38.  https://doi.org/10.1007/9781441999146_3
  13. 13.
    Mensurado S, Balkwill FR, Pennington DJ et al (2014) Murine CD27(-) V 6(+) T cells producing IL-17A promote ovarian cancer growth via mobilization of protumor small peritoneal macrophages. Proc Natl Acad Sci 111:E3562–E3570.  https://doi.org/10.1073/pnas.1403424111 CrossRefGoogle Scholar
  14. 14.
    Ma S, Wu Y, Shi L et al (2014) IL-17A produced by T cells promotes tumor growth in hepatocellular carcinoma. Cancer Res 74:1969–1982.  https://doi.org/10.1158/0008-5472.can-13-2534 CrossRefGoogle Scholar
  15. 15.
    Kolls JK, McAllister F, Pardoll DM et al (2014) Oncogenic Kras activates a hematopoietic-to-epithelial IL-17 signaling axis in preinvasive pancreatic neoplasia. Cancer Cell 25:621–637.  https://doi.org/10.1016/j.ccr.2014.03.014 CrossRefGoogle Scholar
  16. 16.
    Staats R, Rodrigues R, Barros A, Bacelar-Nicolau L, Aguiar M, Fernandes D, Moreira S, Simões A, Silva-Santos B, Rodrigues JV, Barbara C, de Almeida AB, Moita LF (2018) Decrease of perforin positive CD3+γδ-T cells in patients with obstructive sleep disordered breathing. Sleep Breath 22:211–221.  https://doi.org/10.1007/s11325-017-1602-6 CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Richard Staats
    • 1
  • Raquel Rodrigues
    • 2
    • 3
  • André Barros
    • 2
  • Leonor Bacelar-Nicolau
    • 4
  • Margarida Aguiar
    • 1
  • Dina Fernandes
    • 1
  • Susana Moreira
    • 1
    • 2
  • André Simões
    • 5
  • Bruno Silva-Santos
    • 5
  • João Valença Rodrigues
    • 1
  • Cristina Barbara
    • 1
  • António Bugalho de Almeida
    • 1
  • Luís F. Ferreira Moita
    • 2
    Email author
  1. 1.Departamento de PneumologiaHospital de Santa MariaLisbonPortugal
  2. 2.Innate Immunity and Inflammation LaboratoryInstituto Gulbenkian de CiênciaOeirasPortugal
  3. 3.Departamento de Pediatria, Serviço de Genética MédicaHospital de Santa MariaLisbonPortugal
  4. 4.Instituto de Medicina Preventiva and ISAMB, Faculdade de MedicinaUniversidade de LisboaLisbonPortugal
  5. 5.Instituto de Medicina Molecular, Faculdade de MedicinaUniversidade de LisboaLisbonPortugal

Personalised recommendations