Association between insomnia and type 2 diabetes mellitus in Han Chinese individuals in Shandong Province, China
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Diabetes and sleep disorders are public health threats worldwide, but the potential association between them is still unclear.
We conducted a community-based cross-sectional study including 5078 participants (2665, 52.5% male) to determine the association between insomnia and diabetes mellitus prevalence.
In patients with type 2 diabetes mellitus (T2DM) and nondiabetic controls, the prevalence of insomnia was 20.2% (68/377) and 12.2% (578/4741), respectively. The results showed that insomnia was associated with T2DM after adjusting for age, sex, BMI, smoking, alcohol consumption, presence of disease history (hypertension, dyslipidemia, stroke, cardiovascular diseases, cancers), and depression (odds ratio [OR] = 1.31, 95% confidence interval [CI] 1.03–1.66). After stratifying by age and sex, insomnia was significantly associated with diabetes mellitus only in the subgroup of middle-aged participants (40–59 years) (OR = 1.61, 95% CI 1.16–2.23) and males (OR = 1.48, 95% CI 1.08–2.03) after controlling for the above covariates.
This study suggests that insomnia is independently and significantly associated with diabetes mellitus in the northern Chinese population, especially in the 40–59-year-old age group and in males.
KeywordsInsomnia Sleep duration Diabetes mellitus Athens insomnia scale Cross-sectional study
This work was supported by the National Key Technology Research and Development Program of the Ministry of Science and Technology of China (2015BAI06B05). The sponsor had no role in the design or conduct of this research.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
All procedures performed in studies involving human participants were in accordance with the ethical standards of Weifang Maternity and Child Health Hospital and with the 1964 Declaration of Helsinki and its later amendments or with comparable ethical standards.
Informed consent was obtained from all individual participants included in the study.
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