Sleep and Breathing

, Volume 19, Issue 4, pp 1199–1203 | Cite as

White coat hypertension and obstructive sleep apnea

  • Li LiEmail author
  • Li-zhu Guo
  • Jie Li
  • Ying Wang
  • Xin Liu
  • Ya-hui Lv
  • Chang-sheng Ma
Original Article



This study aimed to determine blood pressure characteristics and long-term progress in patients with white coat hypertension (WCH) and obstructive sleep apnea (OSA).


Systolic blood pressure (SBP) and diastolic blood pressure (DBP) and sleep test results over a period of 26 months were analyzed from WCH patients with OSA (n = 28), WCH patients (n = 23), and healthy control subjects (n = 27).


At the end of observation, WCH patients with OSA presented significantly increased daytime and nighttime BP and lower diurnal difference of SBP (all Ps < 0.05) and the increased rate of “non-dipper” status (SBP 28.6 %, DBP 32.1 %) was significantly higher when compared with WCH and control groups (all Ps < 0.01). Sustained hypertension was observed in 42.8 % of the WCH patients with OSA, which was significantly higher than that in the WCH and control groups (Ps < 0.01) and was predicted by non-dipper status via 24-h ambulatory SBP/DBP monitoring (Ps < 0.05).


WCH may represent a prehypertension status, which could develop into sustained hypertension with OSA.


Blood pressure Non-dipper Obstructive sleep apnea White coat hypertension 


Conflict of interest

The authors declare no conflict of interest.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  • Li Li
    • 1
    Email author
  • Li-zhu Guo
    • 1
  • Jie Li
    • 1
  • Ying Wang
    • 1
  • Xin Liu
    • 1
  • Ya-hui Lv
    • 1
  • Chang-sheng Ma
    • 1
    • 2
  1. 1.Cardiovascular Center, Beijing Tong Ren HospitalCapital University of Medical SciencesBeijingChina
  2. 2.Atrial Fibrillation Center, Cardiology Department, Beijing An Zhen HospitalCapital University of Medical SciencesBeijingChina

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