Sleep and Breathing

, Volume 17, Issue 1, pp 373–379

Negative association between self-reported jaw symptoms and apnea–hypopnea index in patients with symptoms of obstructive sleep apnea syndrome: a pilot study

  • Takafumi Kato
  • Akira Mikami
  • Hideko Sugita
  • Hisae Muraki
  • Mutsumi Okura
  • Motoharu Ohi
  • Mitsutaka Taniguchi
Original Article



Prior to oral appliance therapy for snoring and obstructive sleep apnea syndrome (OSAS), patients are screened for jaw symptoms (e.g., pain). However, the presence of jaw symptoms in a large spectrum of OSAS patients remains unknown. This study aimed to assess the distribution of subjective jaw symptoms in patients with symptoms of OSAS.


Five hundred and eleven consecutive patients (66 female, 445 male; mean age 49.6 ± 12.6 years) with clinical symptoms of OSAS were enrolled for cardiorespiratory evaluation. Self-administered questionnaires were used to assess jaw symptoms, tooth grinding and clenching during sleep, morning oral dryness, morning heartburn sensation, and pain in the neck and back.


The mean apnea–hypopnea (AHI) index was 32.5 ± 30.6 per hour of sleep. Nineteen percent of patients (n = 96) reported at least one jaw symptom. The presence of jaw symptoms was more frequently reported by patients with AHI less than 15 (25 %) than those with AHI of 15 and more (15 %, p = 0.012). In the crude analyses, jaw symptoms were associated with tooth grinding, tooth clenching, morning oral dryness, morning heartburn sensation, and neck/back pain. Multiple logistic regression analysis confirmed that jaw symptoms were associated with AHI less than 15 (odds ratio (OR) 1.99, p = 0.009), tooth clenching (OR 1.79, p = 0.006), morning oral dryness (OR 2.17, p = 0.02), and neck/back pain (OR 1.99, p = 0.005).


Jaw symptoms can be found in 19 % of patients with symptoms of OSAS and are more frequently reported in patients with lower AHI, a patient population for whom oral appliances are often prescribed.


Obstructive sleep apnea AHI Self-report Cardiorespiratory evaluation Jaw symptoms Tooth grinding Oral dryness 


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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Takafumi Kato
    • 1
  • Akira Mikami
    • 2
  • Hideko Sugita
    • 3
  • Hisae Muraki
    • 3
  • Mutsumi Okura
    • 3
  • Motoharu Ohi
    • 3
  • Mitsutaka Taniguchi
    • 3
  1. 1.Department of Oral Anatomy and Neurobiology, Graduate School of DentistryOsaka UniversitySuitaJapan
  2. 2.Osaka University Health Care CenterMinooJapan
  3. 3.Sleep Medical CenterOsaka Kaisei HospitalYodogawaJapan

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