Sleep and Breathing

, Volume 16, Issue 4, pp 1129–1137

Sleep quality and asthma control and quality of life in non-severe and severe asthma

  • Faith S. Luyster
  • Mihaela Teodorescu
  • Eugene Bleecker
  • William Busse
  • William Calhoun
  • Mario Castro
  • Kian Fan Chung
  • Serpil Erzurum
  • Elliot Israel
  • Patrick J. Strollo
  • Sally E. Wenzel
Original Article

Abstract

Purpose

The effect of sleep quality on asthma control independent from common comorbidities like gastroesophageal reflux disease (GERD) and obstructive sleep apnea (OSA) is unknown. This study examined the association between sleep quality and asthma control and quality of life after accounting for OSA and GERD in non-severe (NSA) and severe (SA) asthma.

Methods

Cross-sectional data from 60 normal controls, 143 with NSA, and 79 with SA participating in the Severe Asthma Research Program was examined. Those who reported using positive airway pressure therapy or were at high risk for OSA were excluded.

Results

Both SA and NSA had poorer sleep quality than controls, with SA reporting the worst sleep quality. All asthmatics with GERD and 92% of those without GERD had poor sleep quality (p = 0.02). The majority (88–100%) of NSA and SA participants who did not report nighttime asthma disturbances still reported having poor sleep quality. In both NSA and SA, poor sleep quality was associated with worse asthma control and quality of life after controlling for GERD and other covariates.

Conclusions

These results suggest that poor sleep quality is associated with poor asthma control and quality of life among asthmatics and cannot be explained by comorbid GERD and nighttime asthma disturbances.

Keywords

Asthma control Gastroesphogeal reflux disease Sleep 

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Faith S. Luyster
    • 1
  • Mihaela Teodorescu
    • 2
  • Eugene Bleecker
    • 3
  • William Busse
    • 2
  • William Calhoun
    • 4
  • Mario Castro
    • 5
  • Kian Fan Chung
    • 6
  • Serpil Erzurum
    • 7
  • Elliot Israel
    • 8
  • Patrick J. Strollo
    • 9
  • Sally E. Wenzel
    • 9
    • 10
  1. 1.University of Pittsburgh School of NursingPittsburghUSA
  2. 2.University of Wisconsin School of MedicineMadisonUSA
  3. 3.Wake Forest University School of MedicineWinston-SalemUSA
  4. 4.University of Texas Medical Branch at GalvestonGalvestonUSA
  5. 5.Washington University School of Medicine, St. LouisSt. LouisUSA
  6. 6.Imperial College London School of MedicineLondonUK
  7. 7.The Cleveland ClinicClevelandUSA
  8. 8.Brigham and Women’s HospitalBostonUSA
  9. 9.Division of Pulmonary, Allergy, and Critical Care Medicine, Department of MedicineUniversity of PittsburghPittsburghUSA
  10. 10.The University of Pittsburgh Asthma Institute at UPMCUniversity of Pittsburgh School of MedicinePittsburghUSA

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