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Sleep and Breathing

, Volume 13, Issue 1, pp 85–88 | Cite as

Urinary levels of catecholamines among individuals with and without sleep bruxism

  • Paula Seraidarian
  • Paulo Isaías Seraidarian
  • Bruno das Neves Cavalcanti
  • Leonardo MarchiniEmail author
  • Ana Christina Claro Neves
Original Article

Abstract

Introduction

Sleep bruxism (SB) is characterized by repetitive and coordinated mandible movements and non-functional teeth contacts during sleep time. Although the etiology of SB is controversial, the literature converges on its multifactorial origin. Occlusal factors, smoking, alcoholism, drug usage, stress, and anxiety have been described as SB trigger factors. Recent studies on this topic discussed the role of neurotransmitters on the development of SB.

Objective

Thus, the purpose of this study was to detect and quantify the urinary levels of catecholamines, specifically of adrenaline, noradrenaline and dopamine, in subjects with SB and in control individuals.

Materials and methods

Urine from individuals with SB (n = 20) and without SB (n = 20) was subjected to liquid chromatography. The catecholamine data were compared by Mann–Whitney’s test (p ≤ 0.05).

Results

Our analysis showed higher levels of catecholamines in subjects with SB (adrenaline = 111.4 µg/24 h; noradrenaline = 261,5 µg/24 h; dopamine = 479.5 µg/24 h) than in control subjects (adrenaline = 35,0 µg/24 h; noradrenaline = 148,7 µg/24 h; dopamine = 201,7 µg/24 h). Statistical differences were found for the three catecholamines tested.

Conclusion

It was concluded that individuals with SB have higher levels of urinary catecholamines.

Keywords

Sleep bruxism Etiology Catecholamines Adrenaline Noradrenaline Dopamine Urine 

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Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Paula Seraidarian
    • 1
  • Paulo Isaías Seraidarian
    • 2
  • Bruno das Neves Cavalcanti
    • 1
    • 3
  • Leonardo Marchini
    • 1
    • 4
    • 5
    • 6
    Email author
  • Ana Christina Claro Neves
    • 1
  1. 1.Universidade de TaubatéTaubatéBrazil
  2. 2.Pontifícia Universidade Católica de Minas GeraisBelo HorizonteBrazil
  3. 3.Universidade IbirapueraSão PauloBrazil
  4. 4.Universidade do Vale do ParaíbaSão José dos CamposBrazil
  5. 5.State University of São Paulo-UNESPSão José dos CamposBrazil
  6. 6.S.J. CamposBrazil

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