Oral Radiology

, Volume 34, Issue 3, pp 199–207 | Cite as

Dense cancellous bone as evidenced by a high HU value is predictive of late implant failure: a preliminary study

  • Ikuya Miyamoto
  • Tetsu Takahashi
  • Tatsurou Tanaka
  • Bunichi Hirayama
  • Kenko Tanaka
  • Toru Yamazaki
  • Yasuhiro Morimoto
  • Izumi Yoshioka
Original Article



The mechanism of late implant failure is unclear. This study examined the association between sclerosing cancellous bone images and the risk of late implant failures using multi-detector row computed tomography (CT) imaging data.


We performed a case–control study. The study group consisted of consecutive patients with implant failures treated at Kyushu Dental University between 2001 and 2016. CT data for late failure of 36 implants in 16 patients were available. The study cohort consisted of 16 patients with 36 late failed implants and 28 patients with 113 successful implants.


The mean survival rate was 6.9 months for early implant failure, 76.6 months for late failure with marginal bone resorption, inflammation symptoms, and so-called peri-implantitis, and 95.0 months for late failure caused by implant fracture. The mean HU value for cases in the control group was 507 compared with 1231 for cases with late failure implants. Logistic regression was used for analysis. There were signs of high radiodensity of peri-implant cancellous bone when comparing adjusted radiodensity per 100 HU using CT data (OR 2.35; 95% CI 1.73–3.20; p < 0.001).


Within the limits of our study, the presence of high radiodensity and cancellous bone consolidation on imaging may be related to risk factors for late implant failure. Therefore, CT images of the host cancellous bone status for observation of visible sclerosis could be a useful diagnostic indicator for late implant failure.


Late implant failure Cancellous bone Bone sclerosing image 



The authors would like to thank Chief Prof. Kazuhiro Tominaga (Department of Science of Physical Functions, Division of Oral and Maxillofacial Surgery, Kyushu Dental University) for his support.

Compliance with ethical standards

Conflict of interest

Ikuya Miyamoto, Tetsu Takahashi, Tatsurou Tanaka, Bunichi Hirayama, Kenko Tanaka, Toru Yamazaki, Yasuhiro Morimoto, and Izumi Yoshioka declare that they have no conflict of interest.

Human rights statement

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964 and later versions.

Informed consent

Informed consent was obtained from all patients for being included in the study.

Ethical statement

The Ethical Committee of Kyushu Dental University approved the study protocol (Approval Number: 2013 12-38). The STROBE guideline was followed in this investigation.


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Copyright information

© Japanese Society for Oral and Maxillofacial Radiology and Springer Japan KK 2017

Authors and Affiliations

  • Ikuya Miyamoto
    • 1
  • Tetsu Takahashi
    • 2
  • Tatsurou Tanaka
    • 3
  • Bunichi Hirayama
    • 2
  • Kenko Tanaka
    • 2
  • Toru Yamazaki
    • 4
    • 5
  • Yasuhiro Morimoto
    • 3
  • Izumi Yoshioka
    • 6
  1. 1.Division of Oral and Maxillofacial Surgery, Department of Oral and Maxillofacial Reconstructive Surgery, School of DentistryIwate Medical UniversityMoriokaJapan
  2. 2.Division of Oral and Maxillofacial Surgery, Department of Oral Medicine and SurgeryTohoku University Graduate School of DentistrySendaiJapan
  3. 3.Division of Oral RadiologyKyushu Dental UniversityKitakyushuJapan
  4. 4.Department of Public Health and Occupational MedicineMie University Graduate School of MedicineTsuJapan
  5. 5.Epidemiology Centre for Disease Control and PreventionMie University HospitalTsuJapan
  6. 6.Division of Oral MedicineKyushu Dental University, KitakyushuKitakyushuJapan

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