Fusarium solani, Tax-3, a new endophytic taxol-producing fungus from Taxus chinensis
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An endophytic fungus, Tax-3, was isolated from barks of Taxus chinensis grown in the Qinba mountains, China. The strain was classified into Fusarium solani based on the morphological characteristics and the molecular phylogenetics inferred from the nuclear ribosomal DNA ITS sequences with the sequence similarity values of 100%. High performance liquid chromatography (HPLC) assay showed the F. solani, Tax-3, produced taxol with a higher yield of 163.35 μg/L in the reformative potato dextrose liquid medium (d), revealing its potential applications for taxol production.
KeywordsEndophytic fungi Fusarium solani ITS sequence Phylogenetic analysis Taxol Taxus chinensis
We would like to thank Tajalli Keshavarz and anonymous reviewers for their critical reviews of the manuscript and acknowledge Dr. Bin Liu for critical reading of the manuscript. The work was supported jointly by projects from Shaanxi Educational Committee (08JZ21, 08JK244, 08JK248).
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