Kinetic and Thermodynamic Behavior on the Sorption of Clindamycin from an Aqueous Medium by Modified Surface Zeolitic Tuffs
- 192 Downloads
Clindamycin (CLD), an antibiotic derivate of lincomycin, is widely used; the presence of this drug in the wastewater and the environment could produce resistance in bacteria. In this work, the sorption of this drug by two surfactant-modified zeolitic tuffs was studied considering contact time, initial concentration, pH, and temperature. The kinetic behavior indicates that the equilibrium times were between 15 and 12 h for all materials, and the results were best adjusted to Ho and Mc Kay model. The highest adsorption was obtained with the hexadecyltrimethylammonium-modified zeolitic tuff from Oaxaca, Mexico (1.56 mg/g). The sorption isotherms obtained showed a linear behavior, indicating a partition mechanism. The thermodynamic parameters were determined from the isotherms at different temperatures and Van Ho equation; the processes are exothermic and not spontaneous. The best pH for the adsorption is between 8 and 11. The results show that the modified zeolitic tuffs are potential materials for the adsorption of CLD from water.
KeywordsClindamycin Sorption Zeolitic tuff Surfactant Kinetics Thermodynamic parameters
The authors acknowledge the financial support from the CONACYT (Project 215997) and CONACYT scholar grant no. 556031 for AGO.
- Cappelletti, A., Conella, A., Langella, M., Mercurio, L., Catalanotti, V., & Monetti, B. D. (2015). Use of surface modified natural zeolite (SMNZ) in pharmaceutical preparations. Part 1. Mineralogical and technological characterization of some industrial zeolite rich-rocks. Microporous and Mesoporous Materials, 250, 232–244.CrossRefGoogle Scholar
- Colella, C., & Mumpton, F. A. (2000). Natural zeolites for the third millennium, ICNZ, International Committee on Natural Zeolites. Italy: De Frede Editore.Google Scholar
- (FEUM) Farmacopea de los Estados Unidos Mexicanos. (2014). Secretaria de Salud, México.Google Scholar
- ICH Q2A. (2009). Validation of analytical procedures: text and methodology. European Medicine Agency Web http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2009/09/WC500002662.pdf. Accessed 20 June 2017.
- ICH Q2B. (2009). Validation of analytical procedures. European Medicine Agency Web http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2009/09/WC500002662.pdf. Accessed 20 June 2017.
- Leyva-Ramos, R., Medellín-Castillo, N. A., Guerrero-Coronado, R. M., Berber-Mendoza, M. S., Aragón Piña, A., & Azuara, J. A. (2005). Intercambio iónico de plata (I) en solución acuosa sobre clinoptilolita. Revista Internacional de Contaminación Ambiental, 4, 193–200.Google Scholar
- Li, Y., Hu, X., Zhang, Y., Zhao, Q., Ning, P., & Tian, S. (2017). Adsorption behavior of phenol by reversible surfactant-modified montmorillonite: Mechanism, thermodynamics, and regeneration. Chemical Engineering Journal, 334(15), 1214–1221.Google Scholar
- Lv, Y. K., Wang, L. M., Yan, S. L., Wang, X. H., & Sun, H. W. (2012). Synthesis and characterization of molecularly imprinted poly(methacrylic acid)/silica hybrid composite materials for selective recognition of lincomycin in aqueous media. Journal of Applied Polymer Science, 126, 1631–1636.CrossRefGoogle Scholar
- Solache-Ríos, M. J., Villalba-Coyote, R., & Díaz-Nava, M. C. (2010). Sorption and desorption of remazol yellow by a Fe-zeolitic tuff. Journal Mexican Chemistry Society, 54(1), 59–68.Google Scholar
- USP (United States Pharmacopeia) 40/National Formulary (NF) 35. (2017). Food and Drug Administration (FDA), USA.Google Scholar