Evolutionary forces at work in partitiviruses
The family Partitiviridae consists of dsRNA viruses with genome separated into two segments and encoding replicase and capsid protein only. We examined the nucleotide diversity expressed as the ratio dN/dS of nonsynonymous and synonymous substitutions, which has been calculated for 12 representative viruses of all five genera of partitiviruses. We can state that strong purifying selection works on both the RdRp and CP genes and propose that putative positive selection occurs also on the RdRp genes in two viruses. Among the 95 evaluated viruses, wherein both segments had been sequenced, 8 viruses in betapartitiviruses and 9 in alphapartitiviruses were identified as reassortment candidates because they differ extremely in their CP identity even as they are related in terms of RdRp. Furthermore, there are indications that reassortants are present among isolates of different viruses.
KeywordsCapsid protein Negative/positive selection Reassortment RNA polymerase Symbiosis
This work has been funded by institutional support RVO60077344 and Grant MEMOBiC of the Ministry of Education, Youth and Sports of the Czech Republic.
Compliance with ethical standards
Conflict of interest
The author declares no conflict of interest.
This article does not contain any experiments with human participants or animals and is in compliance with ethical standards for research.
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