Genome sequence and characterization of a Rhodococcus equi phage REQ1
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Rhodococcus equi is a pathogenic member of the Actinobacteria responsible for causing serious infections in equines. A novel Siphoviridae bacteriophage (REQ1) lytic in R. equi was isolated and characterized. The genome size of REQ1 is 51,342 bp, and its sequence shares 7 % similarity to other DNA sequence in GenBank. Putative open reading frames were identified, and their functions were identified based on their predicted amino acid similarities. REQ1 phage has a modular genome, a feature common in double-stranded DNA phages.
KeywordsRhodococcus equi Actinobacteria REQ1 bacteriophage
The research was supported by the Australian Research Council Linkage Grant (LP0774913) together with Melbourne Water and South East Water who are thanked for their financial support. S. Petrovski was funded by the ARC Linkage and La Trobe University grants.
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