A long term feed supplementation based on phosphate binders in Feline Chronic Kidney Disease

  • E. Biasibetti
  • E. Martello
  • M. Bigliati
  • I. Biasato
  • T. Cocca
  • N. Bruni
  • M. T. Capucchio
Original Article

Abstract

Chronic kidney disease (CKD) is a very common disorder in elderly cats. A proper renal diet represents the most efficient therapeutic intervention to improve survival and life quality in feline patients with 3 and 4 International Renal Interest Society (IRIS) stages. Twenty cats were selected in this study. Ten were administered the dietary supplementation for 360 days and the other ten, whose owners did not give consent for any supplemental therapies apart from the renal diet, were selected from a clinical database and used as control group. The present study is a long term study (360 days) aiming to evaluate the efficacy and palatability of a dietary supplementation containing calcium carbonate, calcium-lactate gluconate, chitosan and sodium bicarbonate in cats diagnosed with 3 and 4 IRIS stages of CKD. The owners were asked to fill in questionnaires to get information on the cat’s appetite, the palatability of the given supplement, the presence of vomit and/or diarrhoea, general health and vitality. Hematochemical, biochemical and urinary analyses were performed on day 0, 30, 60, 90, 120, 150,180 and 360. GraphPad Prism® software was used to perform statistical analysis. Our study shows that the given dietary supplement reduced serum phosphorus and increased serum bicarbonate values in cats with CKD. In turn, this supplement could be used as a support therapy in cats with advanced CKD improving their clinical conditions without any adverse reaction. Finally, it is important to underline that all the animals completed the study and the owners reported a good palatability of the feed supplement.

Keywords

Cat Chronic kidney disease Feed supplement Phosphate binder 

Notes

Compliance with Ethical Standards

Ethical approval

All procedures, treatments and animal care were in compliance with the guidelines of the Italian Minister of Health for the care and use of animals (D.L. 4 March 2014 n. 26 and D.L. 27 January 1992 n.116) and UE (Directive 86/609/CEE).

Conflict of interest

Two of the authors are employees of Candioli Farmaceutici S.p.A.

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Copyright information

© Springer Science+Business Media B.V., part of Springer Nature 2018

Authors and Affiliations

  • E. Biasibetti
    • 1
  • E. Martello
    • 1
  • M. Bigliati
    • 2
  • I. Biasato
    • 1
  • T. Cocca
    • 3
  • N. Bruni
    • 2
  • M. T. Capucchio
    • 1
  1. 1.University of TurinGrugliascoItaly
  2. 2.Istituto Farmaceutico Candioli S.p.A.BeinascoItaly
  3. 3.Clinica Veterinaria NapolivetNapoliItaly

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