Veterinary Research Communications

, Volume 31, Issue 3, pp 317–322 | Cite as

Pharmacokinetics of Eprinomectin in Plasma and Milk in Lactating Camels (Camelus dromedarius)

  • M. Bengoumi
  • K. Hidane
  • Bengone-Ndong
  • F. Van-Gool
  • M. Alvinerie
Short Communication



area under the concentration-time curve


maximum concentration


high-performance liquid chromatography


mean residence time


time to reach maximum concentration


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  1. Ali, B.H., Oukessou, M. and Bashir, A.K., 1996. Pharmacokinetic consideration in the camel (Camelus dromedarius). Comparative Biochemistry and Physiology, 115, 1–9PubMedGoogle Scholar
  2. Alvinerie, M., Sutra, J.F. and Galtier P., 1993. Ivermectin in goat plasma and milk after subcutaneous injection. Veterinary Research, 24, 417–421PubMedGoogle Scholar
  3. Alvinerie, M., Sutra, J.F., Galtier P. and Mage, C., 1999a. Pharmacokinetics of eprinomectin in plasma and milk following topical administration to lactating dairy cattle. Research in Veterinary Science, 67, 229–232CrossRefGoogle Scholar
  4. Alvinerie, M., Sutra, J.F., Galtier P. and Mage, C., 1999b. Some pharmacokinetic parameters of eprinomectin in goat following pour-on administration. Veterinary Research Communications, 23, 449–455CrossRefGoogle Scholar
  5. Bengoumi, M. and Faye B., 2002. Camel diseases and herd management in dry areas. 53rd EAAP Meeting, 1–4 September 2002, Cairo, EgyptGoogle Scholar
  6. Bengoumi, M., Vias, G., Kouniba, A. and Faye B., 2002. Camel milk and traditional cheese in sub-Saharan Africa. Proceedings of Cheese Art 2002, 4–9 June 2002, Ragusa, Italy, 77–84Google Scholar
  7. Boyce, W., Kollias, G., Courtney, C.H., Allen, J. and Chalmers, E., 1984. Efficacy of ivermectin against gastrointestinal nematodes in dromedary camels. Journal of the American Veterinary Medicine Association, 185, 1307–1308Google Scholar
  8. Dakkak, A. and Ouheli, H., 1987. Helminthes et helminthoses du dromadaire. Revue bibliographique. Revue Scientifique et Technique del' Office International de Epizooties, 6, 423–445Google Scholar
  9. Dupy, J., Chartier, C., Sutra J.F. and Alvinerie, M., 2001. Eprinomectin in dairy goats, dose influence on plasma lvels and milk excretion. Parasitology Research, 87, 294–298CrossRefGoogle Scholar
  10. Farah, Z., 1993. Composition of camel's milk. Review article. Journal of Dairy Research, 60, 603–626PubMedCrossRefGoogle Scholar
  11. Oukessou, M., Berrag, B. and Alvinerie, M., 1999. A comparative kinetic study of ivermectin and moxidectin in lactating camels (Camelus dromedarius). Veterinary Parasitology, 83, 151–159PubMedCrossRefGoogle Scholar
  12. Shubber, A.H., Oxley, K.J., Khalaf, A.M., Ramahi, H.M., Al-Naqeeb, L.M., Karimi, O. and Jamshidi, K., 2003. Safety and efficacy against mange and nematodes of three formulations of abamectin in Arabian camels. Veterinary Record, 153, 564–566PubMedGoogle Scholar
  13. Sutra, J.F., Chartier, C., Galtier P. and Alvinerie M., 1998. Detrmination of eprinomectin in plasma by high performance liquid chromatography with automated solid phase extraction and fluorescence detection. Analyst, 123, 1525–1527PubMedCrossRefGoogle Scholar
  14. Toutain, P., Alvinerie, M. and Galtier P., 1988. Plasma and milk kinetics of therapeutic doses of ivermectin for dairy cows. Proceedings of the 4th Congress of the European Association of Veterinary Pharmacology and Toxicology, Budapest. Hungary, 165–170Google Scholar
  15. Yamaoka, K., Tanigawara, K., Nakacawa, T. and Uno, T., 1981. A pharmacokinetic analysis program (MULTI) for microcomputer. Journal Pharmacobio-Dynamics, 4, 879–885Google Scholar

Copyright information

© Springer Science + Business Media, Inc. 2007

Authors and Affiliations

  • M. Bengoumi
    • 1
  • K. Hidane
    • 2
  • Bengone-Ndong
    • 3
  • F. Van-Gool
    • 4
  • M. Alvinerie
    • 3
  1. 1.Institut Agronomique et Vétérinaire Hassan IIRabat
  2. 2.Direction Provinciale de l’AgricultureDakhlaMorocco
  3. 3.Station de Pharmacologie et Toxicologie, INRAToulouse
  4. 4.MerialLyonFrance

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