Skip to main content
Log in

Induction of Cytochrome P450 1A by β-naphto-flavon within the Pig Liver and Central Nervous System

  • Published:
Veterinary Research Communications Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abbreviations

BNF:

β-naphtoflavon

CYP1A:

cytochrome P4501A

CYP1A2:

cytochrome P4501A2

CYP1B1:

cytochrome P4501B1

EROD:

ethoxy-resorufin-O-deethylase

MROD:

methoxy-resorufin-O-deethylase

RT-PCR:

real time-PCR

References

  • Arinc, E., Sen, A. and Bozcaarmutlu, A., 2000. Cytochrome P4501A and associated mixed-function oxidase induction in fish as a biomarker for toxic carcinogenic pollutants in the aquatic environment. Pure and Applied Chemistry, 72, 985–994

    CAS  Google Scholar 

  • Beland, P., Deguise, S. and Girard, C., 1993. Toxic compounds and health and reproductive effects in St- Lawrence beluga whales. Journal Great Lakes Research, 19, 766–775

    Article  CAS  Google Scholar 

  • Chung-Davidson, Y., Rees, C.B., Wu, H., Yun, S. and Li, W., 2004. Beta-naphthoflavon induction of CYP1A in brain of juvenile lake trout (Salvelinus namaycush Walbaum). Journal of Experimental Biology, 207, 1533–1542

    Article  PubMed  CAS  Google Scholar 

  • Clemons, J.H., Myers, C.R., Lee, L.E.J., Dixon, D.G. and Bols, N.C., 1998. Induction of cytochrome P4501A by binary mixtures of polychlorinated biphenyls (PCBs) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in liver cell lines from rat and trout. Aquatic Toxicology, 43, 179–194

    Article  CAS  Google Scholar 

  • Dayal, M., Parmar, D., Ali, M., Dhawan, A., Dwivedi, U.N. and Seth, P.K., 2001. Induction of rat brain cytochrome P450s (P450s) by deltamethrin: regional specificity and correlation with neurobehavioral toxicity. Neurotox Res, 3, 351–357

    Article  PubMed  CAS  Google Scholar 

  • Liu, L., Bridges, J.R. and Eyer, C.L., 2001, Effect of cytochrome P40 1A induction on oxidative damage in rat brain, Molecular and Cellular Biochemistry, 223, 89–94

    Article  PubMed  CAS  Google Scholar 

  • Omiecinski, C., Remmel, R. and Hosagrahara, V., 1999. Concise review of the cytochrome P450s and their roles in toxicology. Toxicology Science, 48, 151–156

    Article  CAS  Google Scholar 

  • Ortiz-Delgado, J.B., Sarasquete, C., Behrens, A., Canales, M.L.G. and Segner, H., 2002. Expression, cellular distribution and induction of cytochrome P4501A (CYP1A) in gilthead seabream, Sparus aurata, brain. Aquatic Toxicology, 60, 269–283

    Article  PubMed  CAS  Google Scholar 

  • Walther, B., Ghersi-Egea, J.F., Minn, A. and Seist, G., 1986. Subcellular distribution of cytochrome P450 in the brain. Brain Research, 375, 338–344

    Article  PubMed  CAS  Google Scholar 

  • Waxman, D.J., 1999. P450 gene induction by structurally diverse xenochemicals: Central role of nuclear receptors CAR, PXR, and PPAR. Archives of Biochemistry and Biophysics, 369, 11–23

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to A. Zaghini.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Marvasi, L., Zaghini, A., Gervasi, P.G. et al. Induction of Cytochrome P450 1A by β-naphto-flavon within the Pig Liver and Central Nervous System. Vet Res Commun 30 (Suppl 1), 333–336 (2006). https://doi.org/10.1007/s11259-006-0074-0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11259-006-0074-0

Keywords

Navigation