International Urology and Nephrology

, Volume 51, Issue 2, pp 343–349 | Cite as

The other side of the coin in renal replacement therapies: the burden on caregivers

  • Simge BardakEmail author
  • Serap Demir
  • Eda Aslan
  • Kenan Turgutalp
  • Havva Didem Celikcan
  • Murside Esra Dolarslan
  • Cennet Kılıcarslan
  • Filiz Karasu
  • Ayse Jini Gunes
  • Cemal Kurt
  • Ahmet Kıykım
Nephrology - Original Paper



Living with end-stage renal disease may be burdensome, not only for patients, but also for caregivers. In this study, we aim to compare caregiver burden, psychological symptoms in caregivers of peritoneal dialysis (PD), hemodialysis (HD), and transplantation (TX), and find out associated factors.


A total of 43 PD, 42 HD, 42 TX patients and a total of 127 caregivers that were actively involved with the care of their patients’ dialysis were enrolled. Patients had been on renal replacement therapy at least for 6 months and caregivers had given care at least for 6 months. The World Health Organization Quality of Life short version and hospital anxiety and depression scale (HAD) were applied to the patients. Symptom Checklist-90-Revised and Zarit caregiver burden scale were applied to the caregivers.


Zarit caregiver burden score was found highest in HD group, which was significantly higher than PD and TX. All three groups had similar HAD anxiety scores, whereas the HAD depression score was highest in HD group, lower in PD, and lowest in TX. Quality of life was lowest in HD group. Zarit caregiver burden score was found higher in caregivers with symptoms like somatization, anxiety, obsessive–compulsive, depression, interpersonal sensitivity, psychoticism, paranoid ideation, hostility, and additional psychological symptoms than the ones who did not have these symptoms. Psychological symptoms were similar in PD, HD, and TX groups.


Caregiver burden was found highest in HD group. Educational, social, and psychological support interventions may be considered for caregivers.


Caregivers Caregiver burden Psychological symptoms Renal replacement therapy 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer Nature B.V. 2018

Authors and Affiliations

  • Simge Bardak
    • 1
    Email author
  • Serap Demir
    • 1
  • Eda Aslan
    • 2
  • Kenan Turgutalp
    • 1
  • Havva Didem Celikcan
    • 3
  • Murside Esra Dolarslan
    • 1
  • Cennet Kılıcarslan
    • 1
  • Filiz Karasu
    • 4
  • Ayse Jini Gunes
    • 4
  • Cemal Kurt
    • 4
  • Ahmet Kıykım
    • 1
  1. 1.Department of Internal Medicine, Division of Nephrology, School of MedicineMersin UniversityMersinTurkey
  2. 2.Department of Psychiatry, School of MedicineMersin UniversityMersinTurkey
  3. 3.Department of Biostatistics and Medical InformaticsMersin UniversityMersinTurkey
  4. 4.Department of Internal Medicine, Division of NephrologyMersin State HospitalMersinTurkey

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