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International Urology and Nephrology

, Volume 49, Issue 7, pp 1225–1232 | Cite as

Impact of chronic kidney disease among Korean adults with chronic obstructive pulmonary disease

  • Min Young KimEmail author
  • Sungmin Boo
  • Mijung Yoo
  • Jonghyun Lee
  • Na Ree Kang
Nephrology – Original Paper

Abstract

Purpose

Chronic kidney disease (CKD) is an emerging issue in patients with chronic obstructive pulmonary disease (COPD). In COPD, loss of muscle mass is relatively common finding, and diagnosis of CKD should be based on measured or estimated GFR (Cavailles et al. Eur Respir Rev 22:454–475, 2013; Gosker et al. Am J Clin Nutr 71:1033–1047, 2000; Delanaye and Mariat Nat Rev Nephrol 9:513–522, 2013). We aimed to determine the prevalence and impact of CKD, defined by using chronic kidney disease epidemiology collaboration (CKD-EPI) equation, in COPD patients.

Methods

This study analyzed data of 3393 adults 40 years of age or older who completed pulmonary function tests in the fifth Korea National Health and Nutritional Examination Survey 2012. Participants with normal lung function (NLF) and COPD were included. CKD was defined as an eGFR <60 mL/min/1.73 m2. Multivariate logistic regression analysis was performed to evaluate the relationship between CKD and COPD.

Results

Among 3393 participants, 528 (15.6%) were classified as COPD. The prevalence values of participants with eGFR level ≥90, 60–90, and <60 mL/min/1.73 m2 were 54.1, 43.6, and 2.2% in those with NLF and 39.8, 51.5, and 8.7% in those with COPD (p = 0.000). We analyzed the relationship between COPD and all factors that had a statistically significant association with COPD. The significant factors were older age, lower education, BMI, pulmonary tuberculosis, current bronchial asthma, smoking, and CKD.

Conclusions

In a Korean population ≥40 years old, the prevalence of participants with COPD is 15.6%. CKD is an independent risk factor for COPD. In addition to CKD, older age, lower education, BMI, pulmonary tuberculosis, current bronchial asthma, and smoking are significantly associated with COPD.

Keywords

Chronic kidney disease Chronic obstructive pulmonary disease Adult Prevalence Risk factor 

Notes

Acknowledgments

We thank the Korea Centers for Disease Control and Prevention for making this survey possible.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Copyright information

© Springer Science+Business Media Dordrecht 2017

Authors and Affiliations

  • Min Young Kim
    • 1
    Email author
  • Sungmin Boo
    • 1
  • Mijung Yoo
    • 1
  • Jonghyun Lee
    • 1
  • Na Ree Kang
    • 1
  1. 1.Department of Internal MedicineSeoul Medical CenterSeoulKorea

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