International Urology and Nephrology

, Volume 47, Issue 3, pp 451–455 | Cite as

The possible role of percutaneous tibial nerve stimulation using adhesive skin surface electrodes in patients with neurogenic detrusor overactivity secondary to spinal cord injury

Urology - Original Paper



To compare the effectiveness of percutaneous tibial nerve stimulation (PTNS) using adhesive skin surface electrodes versus solifenacin succinate (SS) in patients with neurogenic detrusor overactivity (NDO) secondary to spinal cord injury (SCI).


A randomized controlled study involving 100 patients with NDO secondary to SCI was conducted. Patients were randomized into two groups. In group A, patients received PTNS using adhesive skin surface electrodes for 4 weeks. In group B, patients underwent SS treatment for 4 weeks. Bladder diaries and incontinence quality of life questionnaire were reviewed before treatment and 2 and 4 weeks after treatment.


Improvement in all bladder diary parameters was statistically significant within each group 2 and 4 weeks after treatment compared to baseline (p < 0.05), but did not reach statistical significance between the PTNS and SS groups (p > 0.05). Compared to SS, PTNS was not associated with any unanticipated adverse events.


PTNS therapy with adhesive skin surface electrodes is an effective method to treat NDO secondary to SCI. This therapy is not only no difference comparing to SS therapy but also noninvasive and easily managed by patients.


Neurogenic detrusor overactivity Spinal cord injury Percutaneous tibial nerve stimulation Solifenacin Succinate Surface electrodes 



This study was supported by China National Technology R&G Program, No. 2012BAI34B02. All experiments were performed at the department of urology of the China Rehabilitation Research Center, Beijing, China. The authors would like to express special thanks to Mr. Chen Jian for technical support and Dr. Ju Lu for the valuable discussions.

Conflict of interest



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Copyright information

© Springer Science+Business Media Dordrecht 2015

Authors and Affiliations

  1. 1.Department of UrologyChina Rehabilitation Research CenterBeijingChina
  2. 2.Department of UrologyCapital Medical UniversityBeijingChina
  3. 3.Neural Electro-Mechanics Center, Chongqing Institute of Green and Intelligent Technology (CIGIT)Chinese Academy of ScienceChongqingChina

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