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International Urology and Nephrology

, Volume 47, Issue 1, pp 101–106 | Cite as

Bladder capacity in kidney transplant patients with end-stage renal disease

  • Miho Song
  • Junsoo Park
  • Young Hoon Kim
  • Duck Jong Han
  • Sang Hoon Song
  • Myung-Soo Choo
  • Bumsik Hong
Urology - Original Paper

Abstract

Introduction

This study evaluated the clinical factors that influence bladder capacity and lower urinary tract dysfunction (LUTD) following kidney transplantation (KT) in end-stage renal disease (ESRD) patients.

Materials and methods

Data were analyzed in ESRD patients who underwent KT between January 2011 and January 2013. The analyzed pre-KT parameters include bladder capacity, vesicoureteral reflux (VUR), postvoid residual urine (PVR), micturition frequency, and voiding volume. Associations between pre-KT parameters, small bladder capacity (<100 cc), and parameters that influence the development of LUTD were also evaluated. LUTD after KT was defined as voiding symptoms that lasted >1 month and required specific treatment.

Results

In total, 622 ESRD patients required KT. The mean age and dialysis duration were 43.9 ± 11.2 years and 59.4 ± 60.7 months. The mean bladder capacity before KT was 300.1 ± 149.8 mL, and 14 % of patients were diagnosed with small bladder capacity. VUR and PVR were observed in 110 (17.5 %) and 83 (13.6 %) patients. Factors associated with small bladder capacity included long-term dialysis, presence of VUR, and PVR (p < 0.001, p = 0.004, p = 0.003). After KT, 31 patients (4.9 %) needed treatment due to LUTD. Factors associated with the development of LUTD included age, VUR, and PVR (p = 0.001 p = 0.034, p < 0.001). Bladder capacity did not affect LUTD after KT.

Conclusion

ESRD patients on long-term dialysis will likely have small bladder capacity and VUR; however, bladder capacity itself is not related to the occurrence of LUTD after KT.

Keywords

End-stage renal disease Bladder capacity Kidney transplantation Lower urinary tract symptom 

References

  1. 1.
    Chen JL, Lee MC, Kuo HC (2012) Reduction of cystometric bladder capacity and bladder compliance with time in patients with end-stage renal disease. J Formos Med Assoc 111:209–213PubMedCrossRefGoogle Scholar
  2. 2.
    Martin X, Aboutaieb R, Soliman S, el Essawy A, Dawahra M, Lefrancois N (1999) The use of long-term defunctionalized bladder in renal transplantation: is it safe? Eur Urol 36:450–453PubMedCrossRefGoogle Scholar
  3. 3.
    Ushigome H, Sakai K, Suzuki T et al (2008) Kidney transplantation for patients on long-term hemodialysis. Transplant Proc 40:2297–2298PubMedCrossRefGoogle Scholar
  4. 4.
    Chun JM, Jung GO, Park JB et al (2008) Renal transplantation in patients with a small bladder. Transplant Proc 40:2333–2335PubMedCrossRefGoogle Scholar
  5. 5.
    Tsunoyama K, Ishida H, Shimizu T, Omoto K, Tanabe K (2012) Improvement of urinary dysfunction after kidney transplantation by administration of the antimuscarinic agent—prospective randomized controlled study. Transplantation 93:597–602PubMedGoogle Scholar
  6. 6.
    Tsunoyama K, Ishida H, Omoto K, Shimizu T, Shirakawa H, Tanabe K (2010) Bladder function of end-stage renal disease patients. Int J Urol 17:791–795PubMedCrossRefGoogle Scholar
  7. 7.
    van der Weide MJ, Hilbrands LB, Bemelmans BL, Kiemeney LA (2004) Lower urinary tract symptoms after renal transplantation: are there changes over time? Urology 63:442–446PubMedCrossRefGoogle Scholar
  8. 8.
    Mitsui T, Shimoda N, Morita K, Tanaka H, Moriya K, Nonomura K (2009) Lower urinary tract symptoms and their impact on quality of life after successful renal transplantation. Int J Urol 16:388–392PubMedCrossRefGoogle Scholar
  9. 9.
    Zermann DH, Janitzky A, Hohne M, Schubert J (2006) Frequency and nocturia after successful renal transplantation: a normal situation? BJU Int 97:555–558PubMedCrossRefGoogle Scholar
  10. 10.
    van der Weide MJ, Hilbrands LB, Bemelmans BL, Meuleman EJ, Frederiks CM (2001) Lower urinary tract symptoms after renal transplantation. J Urol 166:1237–1241PubMedCrossRefGoogle Scholar
  11. 11.
    Castagnetti M, Zhapa E, Berrettini A et al (2010) Lower urinary tract symptoms (LUTS) after renal transplant in non-urologic anuric patients. Pediatr Transplant 14:859–862PubMedCrossRefGoogle Scholar
  12. 12.
    Abrams P, Cardozo L, Fall M et al (2002) The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society. Neurourol Urodyn 21:167–178PubMedCrossRefGoogle Scholar
  13. 13.
    Luke PP, Herz DB, Bellinger MF et al (2003) Long-term results of pediatric renal transplantation into a dysfunctional lower urinary tract. Transplantation 76:1578–1582PubMedCrossRefGoogle Scholar
  14. 14.
    Tanagho EA (1974) Congenitally obstructed bladders: fate after prolonged defunctionalization. J Urol 111:102–109PubMedGoogle Scholar
  15. 15.
    Serrano DP, Flechner SM, Modlin CS, Wyner LM, Novick AC (1996) Transplantation into the long-term defunctionalized bladder. J Urol 156:885–888PubMedCrossRefGoogle Scholar
  16. 16.
    Ghanem MA, Wolffenbuttel KP, De Vylder A, Nijman RJ (2004) Long-term bladder dysfunction and renal function in boys with posterior urethral valves based on urodynamic findings. J Urol 171:2409–2412PubMedCrossRefGoogle Scholar
  17. 17.
    Lyerova L, Lacha J, Skibova J, Teplan V, Vitko S, Schuck O (2001) Urinary tract infection in patients with urological complications after renal transplantation with respect to long-term function and allograft survival. Ann Transplant 6:19–20PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  • Miho Song
    • 1
  • Junsoo Park
    • 1
  • Young Hoon Kim
    • 2
  • Duck Jong Han
    • 2
  • Sang Hoon Song
    • 1
  • Myung-Soo Choo
    • 1
  • Bumsik Hong
    • 1
  1. 1.Department of Urology, Asan Medical CenterUniversity of Ulsan College of MedicineSeoulKorea
  2. 2.Department of Surgery, Asan Medical CenterUniversity of Ulsan College of MedicineSeoulKorea

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