Advertisement

International Urology and Nephrology

, Volume 46, Issue 8, pp 1481–1493 | Cite as

Coffee consumption and urologic cancer risk: a meta-analysis of cohort studies

  • Tian-bao Huang
  • Zhui-feng Guo
  • Xiao-long Zhang
  • Xiao-peng Zhang
  • Huan Liu
  • Jiang Geng
  • Xu-dong Yao
  • Jun-hua ZhengEmail author
Urology - Original Paper

Abstract

Objectives

Controversial results were reported among several epidemiologic studies on the relationship between coffee consumption and urologic cancer risk. We, therefore, conducted this meta-analysis to clarify these associations.

Methods

Electronic databases including Pubmed, Embase and Cochrane library were searched between January 1966 and August 2013 for eligible studies. Pooled relative risk (RR) and its 95 % confidence interval (CI) were calculated. All P values are two tailed.

Results

Thirteen cohorts were eligible for inclusion. As to prostate cancer (PCa), significant reverse association was found among highest versus none/lowest analysis with acceptable heterogeneity (RR 0.86, 95 % CI 0.79–0.95; I 2 25 %, P value for heterogeneity: 0.221). A pooled RR which assessed advanced PCa was 0.73 (with 95 % CI 0.50–1.07), and a slight stronger reverse association was found in fatal PCa. However, a slight insignificant reverse association, basing on 8 studies with 9 outcomes, was found in dose–response analysis (RR 0.98, 95 % CI 0.93–1.03). For kidney and bladder cancer, insignificant associations were found in both highest versus none/lowest analyses and dose–response analyses.

Conclusions

Our findings suggest that coffee consumption may reduce the risk of PCa. No associations were found with both bladder and kidney cancer. Further well-designed large-scaled cohort studies are warranted to provide more definitive conclusions.

Keywords

Coffee Urologic neoplasms Prostatic neoplasms Urinary bladder neoplasms Renal cell carcinoma Meta-analysis 

Notes

Acknowledgments

Tian-bao Huang was responsible for the initial plan, data collection, statistical analysis and for conducting the study. Tian-bao Huang, Yang Yan and Zhui-feng Guo contributed to data collection, data extraction, data interpretation and manuscript drafting. Huan Liu, Xiao-long Zhang, Jiang Geng and Xu-dong Yao contributed to data interpretation and study design. Jun-hua Zheng was the guarantor for this paper and has full responsibility for this study.

Conflict of interest

None.

References

  1. 1.
    Jacobsen BK, Bjelke E, Kvale G, Heuch I (1986) Coffee drinking, mortality, and cancer incidence: results from a Norwegian prospective study. J Natl Cancer Inst 76:823–831PubMedGoogle Scholar
  2. 2.
    Stensvold I, Jacobsen BK (1994) Coffee and cancer: a prospective study of 43,000 Norwegian men and women. Cancer Causes Control 5:401–408PubMedCrossRefGoogle Scholar
  3. 3.
    Ozasa K, Nakao M, Watanabe Y et al (2005) Association of serum phytoestrogen concentration and dietary habits in a sample set of the JACC Study. J Epidemiol 15(Suppl 2):S196–S202PubMedCrossRefGoogle Scholar
  4. 4.
    Nomura AM, Kolonel LN, Hankin JH, Yoshizawa CN (1991) Dietary factors in cancer of the lower urinary tract. Int J Cancer 10(48):199–205CrossRefGoogle Scholar
  5. 5.
    Severson RK, Nomura AM, Grove JS, Stemmermann GN (1989) A prospective study of demographics, diet, and prostate cancer among men of Japanese ancestry in Hawaii. Cancer Res 1(49):1857–1860Google Scholar
  6. 6.
    Ellison LF (2000) Tea and other beverage consumption and prostate cancer risk: a Canadian retrospective cohort study. Eur J Cancer Prev 9:125–130PubMedCrossRefGoogle Scholar
  7. 7.
    Mills PK, Beeson WL, Phillips RL, Fraser GE (1991) Bladder cancer in a low risk population: results from the Adventist Health Study. Am J Epidemiol 1(133):230–239Google Scholar
  8. 8.
    Michaud DS, Spiegelman D, Clinton SK et al (1999) Fluid intake and the risk of bladder cancer in men. N Engl J Med 6(340):1390–1397CrossRefGoogle Scholar
  9. 9.
    Nagano J, Kono S, Preston DL et al (2000) Bladder-cancer incidence in relation to vegetable and fruit consumption: a prospective study of atomic-bomb survivors. Int J Cancer 1(86):132–138CrossRefGoogle Scholar
  10. 10.
    Park CH, Myung SK, Kim TY, Seo HG, Jeon YJ, Kim Y (2010) Coffee consumption and risk of prostate cancer: a meta-analysis of epidemiological studies. BJU Int. 106:762–769PubMedCrossRefGoogle Scholar
  11. 11.
    Zhou Y, Tian C, Jia C (2012) A dose-response meta-analysis of coffee consumption and bladder cancer. Prev Med 55:14–22PubMedCrossRefGoogle Scholar
  12. 12.
    Discacciati A, Orsini N, Andersson SO et al (2013) Coffee consumption and risk of localized, advanced and fatal prostate cancer: a population-based prospective study. Ann Oncol 24:1912–1918PubMedCrossRefGoogle Scholar
  13. 13.
    Bosire C, Stampfer MJ, Subar AF, Wilson KM, Park Y, Sinha R (2013) Coffee consumption and the risk of overall and fatal prostate cancer in the NIH-AARP Diet and Health Study. Cancer Causes Control 24:1527–1534PubMedCentralPubMedCrossRefGoogle Scholar
  14. 14.
    Li Q, Kakizaki M, Sugawara Y et al (2013) Coffee consumption and the risk of prostate cancer: the Ohsaki Cohort Study. Br J Cancer 11(108):2381–2389CrossRefGoogle Scholar
  15. 15.
    Moher D, Liberati A, Tetzlaff J, Altman DG (2010) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Int J Surg. 8:336–341PubMedCrossRefGoogle Scholar
  16. 16.
    Stroup DF, Berlin JA, Morton SC et al (2000) Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis of observational studies in epidemiology (MOOSE) group. JAMA 19(283):2008–2012CrossRefGoogle Scholar
  17. 17.
    Kurahashi N, Inoue M, Iwasaki M, Sasazuki S, Tsugane S (2009) Coffee, green tea, and caffeine consumption and subsequent risk of bladder cancer in relation to smoking status: a prospective study in Japan. Cancer Sci 100:294–914PubMedCrossRefGoogle Scholar
  18. 18.
    Shafique K, McLoone P, Qureshi K, Leung H, Hart C, Morrison DS (2012) Coffee consumption and prostate cancer risk: further evidence for inverse relationship. Nutr J 11:42PubMedCentralPubMedCrossRefGoogle Scholar
  19. 19.
    Washio M, Mori M, Sakauchi F et al (2005) Risk factors for kidney cancer in a Japanese population: findings from the JACC Study. J Epidemiol. 15(Suppl 2):S203–S211PubMedCrossRefGoogle Scholar
  20. 20.
    Wilson KM, Kasperzyk JL, Rider JR et al (2011) Coffee consumption and prostate cancer risk and progression in the health professionals follow-up study. J Natl Cancer Inst 8(103):876–884CrossRefGoogle Scholar
  21. 21.
    Lee JE, Giovannucci E, Smith-Warner SA, Spiegelman D, Willett WC, Curhan GC (2006) Total fluid intake and use of individual beverages and risk of renal cell cancer in two large cohorts. Cancer Epidemiol Biomarkers Prev. 15:1204–1211PubMedCrossRefGoogle Scholar
  22. 22.
    Zeegers MP, Dorant E, Goldbohm RA, van den Brandt PA (2001) Are coffee, tea, and total fluid consumption associated with bladder cancer risk? Results from the Netherlands cohort study. Cancer Causes Control 12:231–238PubMedCrossRefGoogle Scholar
  23. 23.
    Moskal A, Norat T, Ferrari P, Riboli E (2007) Alcohol intake and colorectal cancer risk: a dose-response meta-analysis of published cohort studies. Int J Cancer 1(120):664–671CrossRefGoogle Scholar
  24. 24.
    Aune D, Greenwood DC, Chan DS et al (2012) Body mass index, abdominal fatness and pancreatic cancer risk: a systematic review and non-linear dose-response meta-analysis of prospective studies. Ann Oncol 23:843–852PubMedCrossRefGoogle Scholar
  25. 25.
    Bhathena SJ, Velasquez MT (2002) Beneficial role of dietary phytoestrogens in obesity and diabetes. Am J Clin Nutr 76:1191–1201PubMedGoogle Scholar
  26. 26.
    Wu T, Willett WC, Hankinson SE, Giovannucci E (2005) Caffeinated coffee, decaffeinated coffee, and caffeine in relation to plasma C-peptide levels, a marker of insulin secretion, in US women. Diabetes Care 28:1390–1396PubMedCrossRefGoogle Scholar
  27. 27.
    Russnes KM, Wilson KM, Epstein MM, et al. Total antioxidant intake in relation to prostate cancer incidence in the health professionals follow up study. Int J Cancer. 2013Google Scholar
  28. 28.
    Platz EA, Giovannucci E (2004) The epidemiology of sex steroid hormones and their signaling and metabolic pathways in the etiology of prostate cancer. J Steroid Biochem Mol Biol 92:237–253PubMedGoogle Scholar
  29. 29.
    Kotsopoulos J, Eliassen AH, Missmer SA, Hankinson SE, Tworoger SS (2009) Relationship between caffeine intake and plasma sex hormone concentrations in premenopausal and postmenopausal women. Cancer 15(115):2765–2774CrossRefGoogle Scholar
  30. 30.
    Safarinejad MR (2011) Insulin-like growth factor binding protein-3 (IGFBP-3) gene variants are associated with renal cell carcinoma. BJU Int. 108:762–770PubMedCrossRefGoogle Scholar
  31. 31.
    Bracken MB, Triche E, Grosso L, Hellenbrand K, Belanger K, Leaderer BP (2002) Heterogeneity in assessing self-reports of caffeine exposure: implications for studies of health effects. Epidemiology 13:165–171PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  • Tian-bao Huang
    • 1
    • 2
  • Zhui-feng Guo
    • 1
  • Xiao-long Zhang
    • 1
    • 2
  • Xiao-peng Zhang
    • 1
    • 2
  • Huan Liu
    • 1
    • 2
  • Jiang Geng
    • 1
    • 2
  • Xu-dong Yao
    • 1
    • 2
  • Jun-hua Zheng
    • 1
    • 2
    Email author
  1. 1.Department of Urology, Shanghai Tenth People’s HospitalTongji UniversityShanghaiChina
  2. 2.Department of First Clinical Medical CollegeNanjing Medical UniversityNanjingChina

Personalised recommendations