International Urology and Nephrology

, Volume 44, Issue 6, pp 1617–1622 | Cite as

The impact of simple orchiectomy on semen quality and endocrine parameters in postpubertal cryptorchid men

  • Hasan Cem Irkilata
  • Yusuf Kibar
  • Seref Basal
  • Bulent Kurt
  • Armagan Gunal
  • Bilal Fırat Alp
  • Ender Oral
  • Ugur Musabak
  • Lutfu Tahmaz
  • Murat Dayanc
Urology - Original Paper
First Online:
Received:
Accepted:

Abstract

Purpose

The main objectives of this retrospective cohort study were to evaluate reproductive endocrine and semen profiles before and after simple orchiectomy in patients with unilateral postpubertal cryptorchidism and to investigate the relationship between hormone levels and histopathology of the removed testis.

Methods

We evaluated 40 adult males who were admitted to our clinic, between 2001 and 2007, with unilateral undescended testis. Right orchiectomy was performed in 27 patients and left orchiectomy in 13. Semen analysis, serum inhibin B, follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone levels were examined in before and 3 months after orchiectomy. Orchiectomy materials were evaluated histopathologically.

Results

Semen parameters, as well as testosterone and LH levels, did not change in any histopathological subgroups in the postoperative follow-up. In patients with maturation arrest, mean serum inhibin B level statistically significantly decreased from 160.9 to 83.5 pg/ml, and mean FSH level significantly increased from 4.8 to 7.6 mIU/ml after orchiectomy (p value, 0.008 and 0.008, respectively). Though, the levels were still within the normal range of the two hormones.

Conclusions

Simple orchiectomy does not have any effect on semen parameters and testosterone level in patients with postpubertal cryptorchidism. The change in inhibin B and FSH levels after orchiectomy in patients with maturation arrest is not clinically significant.

Keywords

Cryptorchidism Adult Fertility Hormone 
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Copyright information

© Springer Science+Business Media, B.V. 2012

Authors and Affiliations

  • Hasan Cem Irkilata
    • 1
    • 4
  • Yusuf Kibar
    • 1
  • Seref Basal
    • 1
  • Bulent Kurt
    • 2
  • Armagan Gunal
    • 2
  • Bilal Fırat Alp
    • 1
  • Ender Oral
    • 1
  • Ugur Musabak
    • 3
  • Lutfu Tahmaz
    • 1
  • Murat Dayanc
    • 1
  1. 1.Department of UrologyGulhane Military Medical AcademyAnkaraTurkey
  2. 2.Department of PathologyGulhane Military Medical AcademyAnkaraTurkey
  3. 3.Department of Immunology and AllergyGulhane Military Medical AcademyAnkaraTurkey
  4. 4.Department of UrologyGulhane School of MedicineAnkaraTurkey

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