International Urology and Nephrology

, Volume 41, Issue 1, pp 7–12 | Cite as

Rising incidence of renal cell carcinoma in Ireland

  • Opeyemi A. FalebitaEmail author
  • Silvia Mancini
  • Eamonn Kiely
  • Harry Comber
Urology - Original Paper



To determine the trend in the incidence of renal cell carcinoma in Ireland, and evaluate changes in the modes of presentation and outcomes.


Data on all histologically diagnosed renal cancers in Ireland over a 12-year period (1994–2005) were retrieved from the database of the National Cancer Registry of Ireland. Data on all renal cancer deaths in Ireland in the period 1994–2004 were obtained from the Central Statistics Office.


There were 2,485 cases of renal cell carcinoma from 1994 to 2005, of which 64% were in males and 36% in females. The average age of females at diagnosis fell from 63 years in 1994 to 58 years in 2005, with little change in the average age in males. The age-adjusted incidence of renal cell carcinoma per 100,000 person-year increased from 5.2 in 1994 to 6.8 in 2005, an annual percentage change of +3.4%. The percentage of incidental renal cell carcinoma increased from 5% in 1999 to 21% in 2003. The age-adjusted mortality rate for males increased from 4.8 per 100,000 person-year in 1994 to 7.3 in 2004, while that for females decreased from 2.6 to 2.3 in the same period. There was no overall increase in survival over the study period.


While the incidence of renal cell carcinoma is increasing in Ireland, largely, but not entirely, due to an increase in incidentally diagnosed cancers, mortality is increasing in males only.

Key Words

Incidence Incidental Mortality Renal cell carcinoma Survival 


  1. 1.
    Chow WH, Devesa SS, Warren JL, Fraumeni JF Jr (1999) Rising incidence of renal cell cancer in the United States. JAMA 281:1628–1631. doi: 10.1001/jama.281.17.1628 PubMedCrossRefGoogle Scholar
  2. 2.
    Cheon J, Kim CS, Lee ES et al (2002) Survey of incidence of urological cancer in South Korea: a 15-year summary. Int J Urol 9:445–454. doi: 10.1046/j.1442-2042.2002.00500.x PubMedCrossRefGoogle Scholar
  3. 3.
    Lipworth L, Tarone RE, McLaughlin JK (2006) The epidemiology of renal cell carcinoma. J Urol 176:2353–2358. doi: 10.1016/j.juro.2006.07.130 PubMedCrossRefGoogle Scholar
  4. 4.
    Liu S, Semenciw R, Morrison H et al (1997) Kidney cancer in Canada: the rapidly increasing incidence of adenocarcinoma in adults and seniors. Can J Public Health 88:99–104PubMedGoogle Scholar
  5. 5.
    Marumo K, Kanayama H, Miyao N et al (2007) Prevalence of renal cell carcinoma: a nation-wide survey in Japan, 2002. Int J Urol 14:479–482. doi: 10.1111/j.1442-2042.2007.01739.x PubMedCrossRefGoogle Scholar
  6. 6.
    Nguyen MM, Gill IS, Ellison LM (2006) The evolving presentation of renal carcinoma in the United States: trends from the Surveillance, Epidemiology, and End Results program. J Urol 176:2397–2400. doi: 10.1016/j.juro.2006.07.144 PubMedCrossRefGoogle Scholar
  7. 7.
    Pantuck AJ, Zisman A, Rauch MK, Belldegrun A (2000) Incidental renal tumors. Urology 56:190–196. doi: 10.1016/S0090-4295(00)00655-5 PubMedCrossRefGoogle Scholar
  8. 8.
    Lindblad P (2004) Epidemiology of renal cell carcinoma. Scand J Surg 93:88–96PubMedGoogle Scholar
  9. 9.
    Levi F, Lucchini F, Negri E, La Vecchia C (2004) Declining mortality from kidney cancer in Europe. Ann Oncol 15:1130–1135. doi: 10.1093/annonc/mdh270 PubMedCrossRefGoogle Scholar
  10. 10.
    Sweeney JP, Thornhill JA, Graiger R et al (1996) Incidentally detected renal cell carcinoma: pathological features, survival trends and implications for treatment. Br J Urol 78:351–353PubMedGoogle Scholar
  11. 11.
    Jayson M, Sanders H (1998) Increased incidence of serendipitously discovered renal cell carcinoma. Urology 51:203–205. doi: 10.1016/S0090-4295(97)00506-2 PubMedCrossRefGoogle Scholar
  12. 12.
    Nunnally J World health statistics annual 1995. World Health Organization, GenevaGoogle Scholar
  13. 13.
    Pahernik S, Ziegler S, Roos F et al (2007) Small renal tumors: correlation of clinical and pathological features with tumor size. J Urol 178:414–417. doi: 10.1016/j.juro.2007.03.129 PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, B.V. 2008

Authors and Affiliations

  • Opeyemi A. Falebita
    • 1
    • 2
    Email author
  • Silvia Mancini
    • 3
  • Eamonn Kiely
    • 1
  • Harry Comber
    • 3
  1. 1.Department of UrologyCork University HospitalCorkIreland
  2. 2.CorkIreland
  3. 3.National Cancer RegistryCorkIreland

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