Objective: We prospectively evaluate the safety, morbidity and characteristics of complications for transrectal ultrasound guided needle biopsy of prostate carried out solely by urologists in a single unit. This will help to counsel patient prior to the biopsy. Patients and methods: One hundred consecutive patients were recruited to complete questionnaires prospectively, 2 weeks and 3 months after TRUS and prostate biopsy. Haematospermia, haematuria and rectal bleeding characteristics were evaluated. Pain, analgesia requirement, infection and urinary retention rates were also assessed. Results: Ninety-two patients (92%) returned questionnaires 2 weeks and 63 patients (63%) three months after the biopsy. At 2 weeks questionnaire, 58 patients (63%) experienced haematuria and 9 patients (10%) for more than 1 week. Eighty-five percent of the 58 patients who had haematuria described it as mild and intermittent. Twenty-three (25%) patients experienced a rectal bleed and none for more than four days. Only 1 patient experienced clots with the rectal bleeding. Twelve (13%) patients had difficulty passing urine but the symptoms resolved by day four. Acute urinary retention did not occur. Thirty-five (38%) patients had some degree of discomfort and only one patient had pain for more than three days. Twenty-five (27%) patients took analgesia between 1 and 8 days (Mean 3 days). Two patients had a urinary tract infection despite prophylactic antibiotics. At three months, 4 patients (6%) had experienced secondary haematuria 3 weeks after the biopsy. Two patients experienced more rectal bleeding 2 weeks after the biopsy and 1 patient had residual discomfort 2 weeks after the procedure. Thirteen patients (21%) had haematospermia between day 6 and 56 (Mean 21 days). Conclusions: Transrectal ultrasound guided biopsy of the prostate is generally well tolerated with minor pain and morbidity in our urologist-led service. Our data will assist counselling of patients prior to the procedure.
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KK Hodge JE McNeal MK Terris (1989) ArticleTitleRandom systemic versus directed ultrasound guided transrectal core biopsies of the prostate J Urol 142 71 Occurrence Handle2659827 Occurrence Handle1:STN:280:BiaB1c%2FgslY%3D
G Aus CG Hermannson J Hugosson et al. (1993) ArticleTitleTranrectal ultrasound examination of prostate: complications and acceptance by patients Br J Urol 71 457 Occurrence Handle8499990 Occurrence Handle1:STN:280:ByyB2s3gvFM%3D Occurrence Handle10.1111/j.1464-410X.1993.tb15992.x
KR Ghani D Dundas U Patel (2004) ArticleTitleBleeding after tranrectal ultrasonography-guided prostate biopsy: a study of 7-day morbidity after six-, eight- and 12-core biopsyprotocol BJU Int 94 IssueID7 1014–1020 Occurrence Handle15541119 Occurrence Handle10.1111/j.1464-410X.2004.05096.x
CK Naughton DK Ornstein DS Smith et al. (2000) ArticleTitlePain and morbidity of transrectal ultrasound guided prostate biopsy: a prospective randomised trial of 6 versus 12 cores J Urol 163 168–171 Occurrence Handle10604338 Occurrence Handle1:STN:280:DC%2BD3c%2FmslyhtQ%3D%3D Occurrence Handle10.1016/S0022-5347(05)67996-7
B Djavan M Waldert A Zlotta et al. (2001) ArticleTitleSafety and morbidity of first and repeated transrectal ultrasound guided prostate needle biopsies: results of a prospective European prostate cancer detection study J Urol 166 856–860 Occurrence Handle11490233 Occurrence Handle1:STN:280:DC%2BD3MvksVShtg%3D%3D Occurrence Handle10.1016/S0022-5347(05)65851-X
CE Lee-Elliott D Dundas U Patel (2004) ArticleTitleRandomised trial of lidocaine vs lidocaine/bupivacaine periprostatic injection on longitudinal pain scores after prostate biopsy J Urol 163 158–162
JL Gore SF Shariat BJ Miles et al. (2001) ArticleTitleOptimal combinations of systemic sextant and laterally directed biopsies for the detection of prostate cancer J Urol 165 1554–1559 Occurrence Handle11342916 Occurrence Handle1:STN:280:DC%2BD3M3ovVOitw%3D%3D Occurrence Handle10.1016/S0022-5347(05)66347-1
LV Rodriguez MK Terris (1998) ArticleTitleRisk and complications of transrectal ultrasound guided prostate needle biopsy: a prospective study and review of the literature J Urol 160 2115 Occurrence Handle9817335 Occurrence Handle1:STN:280:DyaK1M%2Fjt1antQ%3D%3D Occurrence Handle10.1016/S0022-5347(01)62255-9
S Torp-Pedersen F Lee PJ Littrup et al. (1989) ArticleTitleTransrectal biopsy of the prostate guided with trans-rectal US. Longitudinal and multiplanar scanning Radiology 170 23–27 Occurrence Handle2642344 Occurrence Handle1:STN:280:BiaD2s3htVA%3D
K Mutaguchi K Shinohara A Matsubara et al. (2005) ArticleTitleLocal anaesthesia during 10 core biopsy of prostate: comparison of 2 methods J Urol 173 742–745 Occurrence Handle15711260 Occurrence Handle10.1097/01.ju.0000152119.28959.3a
T Mkinen A Auvinen M Hakama et al. (2002) ArticleTitleAcceptability and complications of prostate biopsy in population based PSA screening versus routine clinical practice: A prospective, controlled study Urology 60 IssueID5 846–850 Occurrence Handle12429313 Occurrence Handle10.1016/S0090-4295(02)01864-2
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Lee, G., Attar, K., Laniado, M. et al. Safety and detailed patterns of morbidity of transrectal ultrasound guided needle biopsy of prostate in a urologist-led unit. Int Urol Nephrol 38, 281–285 (2006). https://doi.org/10.1007/s11255-006-6671-6
- Prostate biopsy
- Prostate cancer