International Urology and Nephrology

, Volume 37, Issue 3, pp 535–540 | Cite as

Sperm Recovery Prediction in Azoospermic Patients Using Doppler Ultrasonography

  • C. A. B. Souza
  • J. S. L. Cunha-Filho
  • P. Fagundes
  • F. M. Freitas
  • E. P. Passos


Purpose: To evaluate power Doppler ultrasonography to predict sperm recovery in azoospermic patients. Methods: Color Doppler and power Doppler ultrasonography of testis were performed in 38 patients before testicular sperm extraction. Analysis of blood flow included the pulsatility and resistance index of intratesticular vessels and testicular artery, and power Doppler of testis. The results of power Doppler of testis were classified into three categories: 0, no vessels found; 1, one to three vessels; 2, more than three vessels found. Results: Power Doppler of both testis showed a significant difference between obstructive azoospermia and non-obstructive azoospermia (Fisher’s exact test – P = 0.02), and between the groups with and without sperm recovery (Fisher’s exact test – P = 0.001). Doppler indices of intratesticular vessels and testicular artery were similar between the groups. Conclusions: Testicular Power Doppler assessment showed that patients with obstructive azoospermia have better blood flow than patients with non-obstructive azoospermia, and power Doppler is able to predict sperm recovery in azoospermic patients.


Azoospermia Color Doppler Male infertility Testicular sperm extraction Ultrasonography 


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  1. 1.
    Foresta, C, Garolla, A, Bettella, A,  et al. 1998Doppler ultrasound of the testis in azoospermic subjects as a parameter of testicular functionHum Reprod1330903093CrossRefPubMedGoogle Scholar
  2. 2.
    Mansour, RT, Kamal, A, Fahmy, I,  et al. 1997Intracytoplasmic sperm injection in obstructive and non obstructive azoospermiaHum Reprod1219741979CrossRefPubMedGoogle Scholar
  3. 3.
    Silber, SJ, Steirteghem, AC, Nagy, Z,  et al. 1996Normal pregnancies resulting from testicular sperm extraction and intracytoplasmic sperm injection for azoospermia due to maturation arrestFertil Steril66110117PubMedGoogle Scholar
  4. 4.
    Schlegel, PN, Su, LM. 1997Physiological consequences of testicular sperm extractionHum Reprod1216881692CrossRefPubMedGoogle Scholar
  5. 5.
    Tournaye, H, Verheyen, G, Nagy, P,  et al. 1997Are there any predictive factors for successful testicular sperm recovery in azoospermic patients?Hum Reprod128086CrossRefPubMedGoogle Scholar
  6. 6.
    Battaglia, C, Giulini, S, Regnani, G,  et al. 2001Intratesticular Doppler flow, seminal plasma nitrites/nitrates, and nonobstructive sperm extraction from patients with obstructive and nonobstructive azoospermiaFertil Steril7510881094CrossRefPubMedGoogle Scholar
  7. 7.
    Ergun, S, Stingl, J, Holstein, AF. 1994Segmental angioarchitecture of testicular lobule in manAndrologia26143150PubMedGoogle Scholar
  8. 8.
    Eytan, O, Har-Toov, J, Fait, G,  et al. 2001Vascularity index distribution within the testis: a technique for guiding testicular sperm extractionUltrasound Med Biol2711711176CrossRefPubMedGoogle Scholar
  9. 9.
    Souza, CAB, Cunha Filho, JS, Santos, D,  et al. 2003Predictive factors for motile sperm recovery using testicular biopsy in nonobstructive azoospermic patientsInt Urol Nephrol355357CrossRefPubMedGoogle Scholar
  10. 10.
    Ezeh, Ui, Moore, HD, Cooke, ID. 1998A prospective study of multiple needle biopsies versus a single open biopsy for testicular sperm extraction in men with non-obstructive azoospermiaHum Reprod1330753080PubMedGoogle Scholar
  11. 11.
    Westlander, G, Ekerhovd, E, Granberg, S,  et al. 2001Serial ultrasonography, hormonal profile and antisperm antibody response after testicular sperm aspirationHum Reprod1626212627CrossRefPubMedGoogle Scholar
  12. 12.
    Souza CAB, Fagundes P, Cunha F JSL et al. Power Doppler Ultrasonography in non-obstructive and obstructive azoospermia. In: 19th Annual Meeting of the ESHRE, 2003, Madrid. Human Reproduction, Vol. 18. Londres: Oxford University Press, 2003, pp. 197–198.Google Scholar
  13. 13.
    Passos EP, Fagundes P, Cunha F° JSL et al. Serial Power Doppler Ultrasonography after testicular sperm extraction. In: 19th Annual Meeting of the ESHRE, Madrid. Human Reproduction, Vol. 18. Londres: Oxford University Press, 2003. p. 202.Google Scholar
  14. 14.
    Rubin, JM, Bude, RO, Carson, PL,  et al. 1994Power Doppler US: a potentially useful alternative to mean frequency-based color Doppler USRadiology190853856PubMedGoogle Scholar
  15. 15.
    Har-Toov, J, Fait, G, Houser, R,  et al. 2001Can Doppler ultrasonographic measurements of the testis predict spermatozoa retrieval in azoospermic patients undergoing testicular biopsy?Fertil Steril7612761277CrossRefPubMedGoogle Scholar

Copyright information

© Springer 2005

Authors and Affiliations

  • C. A. B. Souza
    • 1
    • 3
  • J. S. L. Cunha-Filho
    • 1
  • P. Fagundes
    • 2
  • F. M. Freitas
    • 1
  • E. P. Passos
    • 1
    • 2
  1. 1.Human Reproduction Center, Hospital de Clínicas de Porto AlegreUniversidade Federal do Rio Grande do SulPorto AlegreBrazil
  2. 2.Serviço de Ecografia e GenéticaPorto AlegreBrazil
  3. 3.Human Reproduction CenterHospital de Clínicas de Porto AlegrePorto AlegreBrazil

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