International Urology and Nephrology

, Volume 37, Issue 1, pp 65–68 | Cite as

Lymphoepithelioma-Like Carcinoma of the Urinary Bladder: A Case Report and Discussion of Differential Diagnosis

  • Servet Guresci
  • Latife Doganay
  • Semsi Altaner
  • H. Irfan Atakan
  • Kemal Kutlu
Article

Abstract

Lymphoepithelioma-like carcinoma (LELC) of the urinary bladder is very rare. It is mandatory to make differential diagnosis among lymphoma, chronic cystitis and LELC because of different therapeutic approach. A bladder tumor was found in a 90-year-old patient suffering from hematuria. After transurethral resection, undifferentiated tumor with prominent lymphoid infiltration was seen on light microscopy. Immunohistochemical examination demonstrated positive staining of tumor cells with cytokeratin (CK), epithelial membrane antigen and CK-20. We presented the case because of its rarity and related literature was reviewed.

Keywords

Bladder Immunohistochemistry Lymphoepithelioma-like carcinoma 

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References

  1. 1.
    Amin, MB, Ro, JY, Lee, KM,  et al. 1994Lymphoepithelioma-like carcinoma of the urinary bladderAm J Surg Pathol18466473PubMedGoogle Scholar
  2. 2.
    Zukerberg LR, Harris NL, Young RH. (1991) Carcinomas of the urinary bladder simulating malignant lymphoma. A report of five cases. Am J Surg Pathol 15(6): 569–576Google Scholar
  3. 3.
    Leyvraz, S, Henle, W, Chahinian, AP,  et al. 1985Association of Epstein–Barr Virus with thymic carcinomaThe New England J Med31212961299Google Scholar
  4. 4.
    Saw, D, Lau W, H, John H, C,  et al. 1986Malignant lymphoepithelial lesion of the salivary glandHum Pathol17914923PubMedGoogle Scholar
  5. 5.
    Mills, SE, Austin, MB, Randall, ME. 1985Lymphoepithelioma-like carcinoma of the uterin cervix. A distinctive, undifferentiated carcinoma with inflammatory stromaAm J Surg Pathol9883889PubMedGoogle Scholar
  6. 6.
    Lopez-Beltran, A, Luque, RJ, Vicioso, L,  et al. 2001Lymphoepithelioma-like carcinoma of the urinary bladder: a clinicopathologic study of 13 casesVirchows Arch438552557CrossRefPubMedGoogle Scholar
  7. 7.
    Constantinides, C, Giannopoulos, A, Kyriakou, G,  et al. 2001Lymphoepithelioma-like carcinoma of the bladderBJU Int87121122CrossRefPubMedGoogle Scholar
  8. 8.
    Ward, JN, Dong, WF, Pitts, WR,Jr. 2002Lymphoepithelioma-like carcinoma of the bladderJ Urol16725232524CrossRefPubMedGoogle Scholar
  9. 9.
    Holmang, S, Borghede, G, Johansson, SL. 1998Bladder carcinoma with lymphoepithelioma-like differentiation: a report of 9 casesJ Urol159779782CrossRefPubMedGoogle Scholar
  10. 10.
    Gulley, ML, Amin, MB, Nicholls, JM,  et al. 1995Epstein–Barr Virus is detected in undifferentiated nasopharyngeal carcinoma but not in lymphoepithelioma-like carcinoma of the urinary bladderHum Pathol2612071214CrossRefPubMedGoogle Scholar
  11. 11.
    Dinney, CP, Ro, JY, Babaian, RJ,  et al. 1993Lymphoepithelioma of the bladder: a clinicopathological study of three casesJ Urol149840842PubMedGoogle Scholar

Copyright information

© Springer 2005

Authors and Affiliations

  • Servet Guresci
    • 1
  • Latife Doganay
    • 1
  • Semsi Altaner
    • 1
  • H. Irfan Atakan
    • 2
  • Kemal Kutlu
    • 1
  1. 1.Department of PathologyTrakya University Medical FacultyEdirneTurkey
  2. 2.Department of UrologyTrakya University Medical FacultyEdirneTurkey

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