Advertisement

Tropical Animal Health and Production

, Volume 51, Issue 4, pp 753–758 | Cite as

The role of goats as reservoir hosts for bovine herpes virus 1 under field conditions

  • Sibel GürEmail author
  • Nural Erol
  • Orhan Yapıcı
  • Mehmet Kale
  • Mehmet Tolga Tan
  • Turhan Turan
  • Mehmet Atilla Çakmak
  • Cemil Tosun
  • Simay Yılmaz
  • Abuzer Acar
  • Işınsu Özenli
  • Coşkun Gür
Regular Articles
  • 184 Downloads

Abstract

Bovine herpesvirus 1 (BoHV1) is the cause of economically significant viral infections in cattle. Respiratory symptoms associated with the infection are known as Infectious Bovine Rhinotracheitis (IBR). Sheep and goats are less sensitive to the infection although their role in inter-species viral transmission under field conditions is subject to controversy. The objective of this study was to investigate seroprevalence of BoHV1 infections in cattle, sheep, and goats raised together for at least a year. Blood serum samples were taken from 226 cattle, 1.053 sheep, and 277 goats from 17 small- to medium-scale farms. BoHV1-specific antibody presence and titers were determined using virus neutralization test. In total, 73 of the 226 cattle (32.3%) were seropositive. The infection was detected in 13 of the 17 farms. Infection rates ranged from 5.8 to 88.8%. Only one of the 1053 sheep (0.09%) was seropositive. However, 58 of the 277 (20.9%) goats were seropositive. Goat samples taken from 8 of the 17 farms were seropositive with infection rates ranging from 17 to 38.9%. Statistical analysis showed a significant correlation in infection rates between cattle and goats but not sheep. These results suggest that goats may be more sensitive to the BHV1 infection than sheep and the role of goats as possible reservoirs for BoHV1 in the control and eradication of BHV1 in cattle should be considered in future studies.

Keywords

BHV1 Cattle Goat Sheep Reservoir 

Notes

Acknowledgments

The authors appreciate the help from Veterinarians Gökçe Elveren, Ersen Şahanoğlu, and Halil İbrahim Önder in sample collection.

Funding information

This study received financial support from the Afyon Kocatepe University, Scientific Research Commission (Approval No. 09.VF.05/2017).

Compliance with ethical standards

The study complied with the Ethical Standard of Animal Ethics Committee of the Afyon Kocatepe University, Afyon, Turkey.

Conflict of interest

The authors declare that they have no conflict of interest.

References

  1. Abu Elzein, E. M. E., Housawi, F. M. T., Al-Afaleq, A. I., Al-Musa, J., 2008. Emergence of clinical infectious Bovine Rhinotracheitis in Eastern Saudi Arabia. Revue d’élevage et de médecine vétérinaire des pays tropicaux, 61, 11–13.CrossRefGoogle Scholar
  2. Albayrak, H., Yazıcı, Z., Okur-Gümüşova, S., 2007. Seroprevalence to bovine herpesvirus type 1 in sheep in Turkey. Veterinarski Arhiv, 77(3), 257–263.Google Scholar
  3. Al-Hammadi, M. A., 2016. Serological Surveillance of Infectious Bovine Rhinotracheitis virus, Bovine viral diarrhea virus and Bovine Parainfluenza-3 virus in Saudi Arabia. Alexandria Journal of Veterinary Sciences, 51, 48–53.CrossRefGoogle Scholar
  4. Alkan, F., Burgu, İ., Bilge Dağalp, S., Yıldırım, Y., Gençay, A., Güngör, B., Ataseven, V. S., Akça, Y., 2005. The seroprevalence of BHV-1 infection on selected dairy cattle herds in Turkey.Google Scholar
  5. Aslan, M. E., Azkur, A. K., Gazyağcı, S., 2015. Epidemiology and genetic characterization of BVDV, BHV-1, BHV-4, BHV-5 and Brucella spp. infections in cattle in Turkey. Journal of Veterinary Medical Science, 77, 1371–1377.CrossRefGoogle Scholar
  6. Bahari, A., Gharekhani, J., Zandieh M., Sadeghi-Nasab, A., Akbarein, H., Karimi-Makhsous, A., Yavari, M., 2013. Serological study of bovine herpes virus type 1 in dairy herds of Hamedan province, Iran. Veterinary Research Forum, 4, 111–114.Google Scholar
  7. Brako, E. E., Fulton, R. W., Nicholson, S. S., Amborski, G. F., 1984. Prevalence of bovine herpesvirus-1, bovine viral diarrhea, parainfluenza-3, goat respiratory syncytial, bovine leukemia, and bluetongue viral antibodies in sheep. American Journal of Veterinary Research, 45(4): 813–816.Google Scholar
  8. Burgu, İ., Akça, Y., 1987. First isolation of IBR virus in Turkey. Tropical Animal Health and Production, 19, 56.CrossRefGoogle Scholar
  9. Çabalar, M., Özgünlük, İ., 2014. Van İlindeki Koyun Sürülerinde Bovine Herpesvirus-1 Antikorlarının Prevalansı. Harran Universitesi Veteriner Fakultesi Dergisi, 3(2), 89–92.Google Scholar
  10. Çeribaşı, A. O., Çeribaşı, S., Özkaraca, M., 2016. Immunohistochemical detection of bovine herpesvirus type 1 and bovine adenovirus type 3 antigens in frozen and paraffinized lung sections of pneumonic sheep and goats. Veterinarski Arhiv, 86(1), 9–21.Google Scholar
  11. Engels, M., Palatini, M., Metzler, A.E., Probst, U., Kihm, U., Ackermann, M., 1992. Interactions of bovine and caprine herpesviruses with the natural and foreign hosts. Veterinary Microbiology, 33, 69–78.CrossRefGoogle Scholar
  12. Gençay, A., Bilge Dağalp, S., Şahna, K., Pınar, D., Başaran, Z., 2009. Kayseri Bölgesindeki Sığırlarda Bovine Herpesvirus Tip 1 (BHV-1) Enfeksiyonunun Seroprevalansı. Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi, 23, 47–52.Google Scholar
  13. Goyal, S. M., Khan, M. A., McPherson, S. W., Robinson, R. A., Boylan, W. J., 1988. Prevalence of antibodies to seven viruses in a flock of ewes in Minnesota. American Journal of Veterinary Research, 49(4), 464–467.Google Scholar
  14. Gürtürk, S., Finci, E., Burgu, İ., 1974. Yurdumuz sığırlarında enfeksiyöz bovine rhinotracheitis (IBR) üzerine araştırmalar. Ankara Universitesi Veteriner Fakültesi Dergisi, 21, 34–46.Google Scholar
  15. Guy, J. S., Potgieter, L. N. D., 1985. Bovine herpesvirus-1 infection of cattle. Kinetics of antibody formation after intranasal exposure and abortion induced by the virus. American Journal of Veterinary Research, 46, 893–898.Google Scholar
  16. Hage, J. J., Vellema, P., Schukken, Y. H., Barkema, H. W., Rijeswik, F. A. M., van Oirschot, J. T., Wentink, G. H., 1997. Sheep do not have a major role in bovine herpesvirus 1 transmission. Veterinary Microbiology, 57, 41–54.CrossRefGoogle Scholar
  17. Kálmán, D., Egyed, L., 2005. PCR detection of Bovine Herpesviruses from nonbovine ruminants in Hungary. Journal of Wildlife Diseases, 41, 482–488.CrossRefGoogle Scholar
  18. Landis, J. R., Koch, G. G., 1977. The measurement of observer agreement for categorical data. Biometrics, 33(1), 159–174.CrossRefGoogle Scholar
  19. Lyaku, J. R., Nettleton, P. F., Mardsen, H., 1992. A comparision of serological relationship among five ruminant alphaherpesviruses by ELISA. Archives of Virology, 124, 333–341.CrossRefGoogle Scholar
  20. Mahmoud, M. A., Ahmed, S. A., 2009. Prevalence of Bovine Herpesvirus-1 in Sheep and Goats in Egypt. Global Veterinaria, 3, 472–479.Google Scholar
  21. Maiga, S., Sarr, J., 1992. Epidemiological survey of the main respiratory viruses of small ruminants in Mali. Revue D’Elevage Et De Medecine Veterinaire Des Pays Tropicaux, 45, 15–17.Google Scholar
  22. Martin, W. B., Catrucci, G., Frigeri, F., Ferrari, M., 1990. A serological comparision of some animal herpesviruses. Comparative Immunology and Microbiology of Infectious Diseases, 13, 75–84.CrossRefGoogle Scholar
  23. Muylkens, B., Thiry, J., Kirten, P., Schynts, F., Thiry, E., 2007. Bovine Herpesvirus 1 infection and infectious bovine rhinotracheitis. Veterinary Research, 38, 181–209.CrossRefGoogle Scholar
  24. Özgünlük, İ., Yıldırım, Y., 2017. Güneydoğu Anadolu Bölgesindeki Sığırlarda Bovine Herpes Virus 1 (BHV 1) ve Bovine Viral Diarrhea Virus (BVDV) Enfeksiyonlarının Serolojik Olarak Araştırılması. Harran Üniversitesi Veteriner Fakültesi Dergisi, 6, 152–157.CrossRefGoogle Scholar
  25. Papanastasopoulou, M., Koptopoulos, G., Lekkas, S., Papadopoulos, O., Ludwig, H., 1991. An experimental study on the pathogenicity of the caprine herpesvirus type 1. Comparative Immunology and Microbiology of Infectious Diseases, 14, 47–53.CrossRefGoogle Scholar
  26. Pirak, M., Thiry, E., Brochier, B., Pastoret, P. P, 1983. Infection expérimentale de la chèvre bpar le virus de la rhinotrachéite infectieuse bovine (bovine herpes virus 1) et tentative de réactivation virale. Annales de Médecine Vétérinaire, 159, 1103–1106.Google Scholar
  27. Roizman, B., Carmichael, L. E., Deinhart, F., De-The, G., Nahmias, A. J., Plowright, W., Rapp, F., Takahashi, M., Wolf, K., 1981. Herpesviridae. Definition, provisional nomenculature and taxonomy. Intervirology, 16, 201–217.CrossRefGoogle Scholar
  28. Rosadio, R. H., Evermann, M. S. J. F., Mueller, G. M., 1984. Spectrum of naturally occuring disease associated with herpesvirus infection of goats and sheep. Agricultural Practice, 5, 20–27.Google Scholar
  29. Rusch, P., Engels, M., Berchtold, M., Wyler, R., 1981. Untersuchungen über den Titerverlauf virusneutralisierender Antikörper nach akuter IBR. Schweizer Archiv Fur Tierheilkunde, 123, 419–247.Google Scholar
  30. Saito, J. K., Gribble, D. H., Berrios, P. E., Knight, H. D., McKercher, D. G., 1974. A new herpesvirus isolate from goats: Preliminary report. American Journal of Veterinary Research, 35, 847–848.Google Scholar
  31. Shirvani, E., Lotfi, M., Kamalzadeh, M., Noaman, V., Bahriari, M., Morovati, H., Hatami, A., 2012. Seroepidemiological study of bovine respiratory viruses (BRSV, BoHV-1, PI-3V, BVDV, and BAV-3) in dairy cattle in central region of Iran (Esfahan province). Tropical Animal Health and Production, 44, 191–195.CrossRefGoogle Scholar
  32. Six, A., Banks, M., Engels, M., Ros Bascuňana, C., Ackermann, M., 2001. Latency and reactivation of bovine herpesvirus 1 (BHV-1) in goats and of caprine herpesvirus 1 (CapHV-1) in calves. Arch. Virol., 146, 1325–1335.CrossRefGoogle Scholar
  33. Suresh, P., Suribabu, T., 1993. Serological survey of bovine herpesvirus 1 (BHV1) in sheep in Andrha Pradesh. Indian Journal of Animal Science, 63, 146–147.Google Scholar
  34. Tan, M. T., Yıldırım, Y., Erol, N., Güngör, B., 2006. The Seroprevalence of Bovine Herpes Virus type 1 (BHV-1) and Bovine Leukemia Virus (BLV) in Selected Dairy Cattle Herds in Aydın Province, Turkey. Turkish Journal of Veterinary and Animal Science, 30, 353–357.Google Scholar
  35. Tolari, F., White, H., Nixon, P., 1990. Isolation and reactivation of bovid herpesvirus 1 in goats. Microbiologica, 13, 67–71.Google Scholar
  36. Trueblood, M. S., Swift, B. L., McHolland-Reymond, L., 1978. A bovine herpesvirus isolated from sheep. Canadian Journal of Comparative Medicine, 42, 97–99.Google Scholar
  37. Tuncer-Göktuna, P., Alpay, G., Öner E. B., Yeşilbağ, K., 2016. The role of herpesviruses (BoHV-1 and BoHV-4) and pestiviruses (BVDV and BDV) in ruminant abortion cases in western Turkey. Tropical Animal Health Production, 48, 1021–1027.CrossRefGoogle Scholar
  38. Wafula, J. S., Mushi, E. Z., Wamwayi, H., 1985. Reaction of goats to infection with infectious bovine rhinotracheitis virus. Research in Veterinary Science, 39, 84–86.CrossRefGoogle Scholar
  39. Wentink, G. H., Van Oirschot, J. T., Verhoeff, J., 1993. Risk of infection with bovine herpesvirus 1: A review. Veterinary Quarterly, 15, 30–33.CrossRefGoogle Scholar
  40. Wyler, R., Engles, M., Schwyzer, M., 1989. Infectious bovine rhinotracheitis/ vulvovaginitis (BHV-1). In: G. Wittmann (eds), Herpesvirus diseases of cattle, horses and pigs. Developments in Veterinary Virology. Boston: Kluwer Academic Publishers, 1–172.Google Scholar
  41. Yang, D. K., Hwang, I. J., Kim, B. H., Kweon, C. H., Lee, K. W., Kang, M. I., Lee, C. S., Cho, K. O., 2008. Serosurveillance of Viral Diseases in Korean Native Goats (Capra hircus). Journal of Veterinary Medical Science, 70(9), 977–979.CrossRefGoogle Scholar
  42. Yeşilbağ K, Bilge-Dağalp S, 2006. Koyunlarda bovine herpesvirus -1 enfeksiyonunun seroprevalansı. Ankara Universitesi Veteriner Fakültesi Dergisi, 53, 141–143.Google Scholar
  43. Yeşilbağ, K., Güngör, B., 2009. Antibody prevalence against respiratory viruses in sheep and goats in North-Western Turkey. Tropical animal health and production, 41, 421–425.CrossRefGoogle Scholar
  44. Yeşilbağ K, Bilge Dağalp S, Okur-Gümüşova S, Güngör B, 2003. Studies on herpesvirus infections of goats in Turkey: prevalence of antibodies to bovine herpesvirus 1. Revue des Médecine Véterinaire, 154, 12, 772–774.Google Scholar
  45. Yıldırım, Y., Yılmaz, V., Faraji Majarashin, A. R., 2009. Kuzeydoğu Anadolu Bölgesi Sınır İllerinde Bulunan Sığırlarda Viral Solunum Sistemi Enfeksiyonlarının Seroprevalansı. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 15, 601–606.Google Scholar
  46. Yılmaz V, Coşkun N, 2016. Investigation of Bovine Herpes Virus Type 1 Infection in Sheep in the Kars Province of Turkey. Harran Universitesi Veteriner Fakultesi Dergisi, 5(1), 40–43.Google Scholar

Copyright information

© Springer Nature B.V. 2018

Authors and Affiliations

  • Sibel Gür
    • 1
    Email author
  • Nural Erol
    • 2
  • Orhan Yapıcı
    • 3
  • Mehmet Kale
    • 4
  • Mehmet Tolga Tan
    • 2
  • Turhan Turan
    • 5
  • Mehmet Atilla Çakmak
    • 6
  • Cemil Tosun
    • 6
  • Simay Yılmaz
    • 7
  • Abuzer Acar
    • 8
  • Işınsu Özenli
    • 7
  • Coşkun Gür
    • 9
  1. 1.Department of Virology, Faculty of Veterinary MedicineAfyon Kocatepe UniversityAfyonkarahisarTurkey
  2. 2.Department of Virology, Faculty of Veterinary MedicineAdnan Menderes UniversityAydınTurkey
  3. 3.Department of Virology, Faculty of Veterinary MedicineSelcuk UniversityKonyaTurkey
  4. 4.Department of Virology, Faculty of Veterinary MedicineMehmet Akif Ersoy UniversityBurdurTurkey
  5. 5.Department of Virology, Faculty of Veterinary MedicineCumhuriyet UniversitySivasTurkey
  6. 6.Ministry of Food, Agriculture and LivestockAfyonkarahisarTurkey
  7. 7.İşlek LLCAfyonkarahisarTurkey
  8. 8.Department of Internal Diseases, Faculty of Veterinary MedicineAfyon Kocatepe UniversityAfyonkarahisarTurkey
  9. 9.Kangal Veterinary ClinicSivasTurkey

Personalised recommendations