Tropical Animal Health and Production

, Volume 46, Issue 5, pp 837–843

Spatial predictors of bovine tuberculosis infection and Brucella spp. exposure in pastoralist and agropastoralist livestock herds in the Ruaha ecosystem of Tanzania

  • Annette Roug
  • Deana Clifford
  • Jonna Mazet
  • Rudovick Kazwala
  • Julius John
  • Peter Coppolillo
  • Woutrina Smith
Regular Articles

Abstract

While many studies investigate animal-related risk factors for disease, few have considered environmental or spatial risk factors in the dynamics of bovine tuberculosis (bTB) and brucellosis. In the Ruaha ecosystem of Tanzania, we investigated the role of household location as a predictor for infection with Mycobacterium bovis and exposure to Brucella in pastoralist and agropastoralist cattle herds in a typical African wildlife-livestock-human interface. ArcGIS was utilized to calculate Euclidian distances between households and the nearest river, village center, protected area, and other infected households, followed by multivariate logistic regression to assess the association between risk factors and herd-level bTB and Brucella outcomes. Global and local spatial clustering of bTB-infected and Brucella-exposed herds was explored using the Cuzick-Edward’s test and SaTScan spatial scan statistics. Households located farther from rivers and closer to village centers and herds belonging to agropastoralists were more likely to have bTB-positive cattle. Risk of Brucella exposure increased with proximity to protected areas. One spatial cluster of households with Brucella spp. seropositive cattle was identified. Spatial factors may be useful for assessing disease risk and for formulating intervention and control strategies for households that manage cattle in ecosystems characterized by seasonally limited resources and intense wildlife-livestock interfaces.

Keywords

Bovine tuberculosis Brucellosis Cattle Spatial predictors Tanzania 

References

  1. Alvarez, J., Perez, A., Bezos, J., Marques, S., Grau, A., Saez, J. L., Minguez, O., de Juan, L. and Dominguez, L., 2012. Evaluation of the sensitivity and specificity of bovine tuberculosis diagnostic tests in naturally infected cattle herds using a Bayesian approach, Veterinary Microbiology, 155, 38-43PubMedCrossRefGoogle Scholar
  2. Cleaveland, S., Shaw, D.J., Mfinanga, S.G., Shirima, G., Kazwala, R.R., Eblate, E. and Sharp, M., 2007. Mycobacterium bovis in rural Tanzania: risk factors for infection in human and cattle populations, Tuberculosis (Edinb), 87, 30-43CrossRefGoogle Scholar
  3. Clifford, D.L., Kazwala, R.R., Sadiki, H., Roug, A., Muse, E.A., Coppolillo, P.C. and Mazet, J.A.K., 2013. Tuberculosis infection in wildlife from the Ruaha ecosystem Tanzania: implications for wildlife, domestic animals, and human health, Epidemiology and Infection, doi:10.1017/S0950268813000836 PubMedGoogle Scholar
  4. Coppolillo, P., 2000. The Landscape ecology of pastoral herding: Spatial analysis of land use and livestock production in East Africa, Human Ecology, 28, 527-560CrossRefGoogle Scholar
  5. Coppolillo, P., Clifford, D. L. and Mazet, J. A. K., 2008. The unintended consequences of development assistance: The case of Usangu in Tanzania, Research Brief 08-02-HALI. Global Livestock Collaborative Research Support Program (CRSP). Available: http://glcrsp.ucdavis.edu/publications/?project=hali. Accessed February 4th, 2014.
  6. Coppolillo, P., Clifford, D., Dickman, A., Masozera, M., Nguvava, M., Kazwala, R., Erickson, J. and Mazet, M., 2009. Landscape factors associated with livestock disease deaths in Idodi and Pawaga Divisions, Tanzania, Research Brief 09-01-HALI. Global Livestock Collaborative Research Support Program (GLCRP). Available: http://glcrsp.ucdavis.edu/publications/?project=hali. Accessed February 4th, 2014.
  7. Courtenay, O., Reilly, L.A., Sweeney, F.P., Hibberd, V., Bryan, S., Ul-Hassan, A., Newman, C., Macdonald, D.W., Delahay, R.J., Wilson, G.J. and Wellington, E.M., 2006. Is Mycobacterium bovis in the environment important for the persistence of bovine tuberculosis? Biology Letters, 2, 460-462PubMedCentralPubMedCrossRefGoogle Scholar
  8. Cuzick, J. and Edwards, R., 1990. Spatial clustering for inhomogeneous populations, Journal of the Royal Statistical Society, Series B, 52, 73 -104Google Scholar
  9. de la Rua-Domenech, R., Goodchild, A. T., Vordermeier, H. M., Hewinson, R. G., Christiansen, K. H. and Clifton-Hadley, R. S., 2006. Ante mortem diagnosis of tuberculosis in cattle: A review of the tuberculin tests, [gamma]-interferon assay and other ancillary diagnostic techniques, Research in Veterinary Science, 81, 190-210PubMedCrossRefGoogle Scholar
  10. De Vos, V., Bengis, R.G., Kriek, N.P., Michel, A., Keet, D.F., Raath, J.P. and Huchzermeyer, H.F., 2001. The epidemiology of tuberculosis in free-ranging African buffalo (Syncerus caffer) in the Kruger National Park, South Africa, Onderstepoort Journal of Veterinary Research, 68, 119-130Google Scholar
  11. Fine, A.E., Bolin, C.A., Gardiner, J.C. and Kaneene, J.B., 2011. A Study of the Persistence of Mycobacterium bovis in the environment under natural weather conditions in Michigan, USA, Veterinary Medicine International, 2011, 765430, doi:10.4061/2011/765430.Google Scholar
  12. Godfroid, J., 2002. Brucellosis in wildlife, Revue Scientifique et Technique Office International des Epizooties, 21, 277-286Google Scholar
  13. Godfroid, J., Nielsen, K. and Saegerman, C., 2010. Diagnosis of brucellosis in livestock and wildlife, Croatian Medical Journal, 51, 296-305PubMedCentralPubMedCrossRefGoogle Scholar
  14. Gomo, C., de Garine-Wichatitsky, M., Caron, A. and Pfukenyi, D.M., 2012. Survey of brucellosis at the wildlife-livestock interface on the Zimbabwean side of the Great Limpopo Transfrontier Conservation Area, Tropical Animal Health and Production, 44, 77-85PubMedCrossRefGoogle Scholar
  15. Gumi, B., Schelling, E., Firdessa, R., Aseffa, A., Tschopp, R., Yamuah, L., Young, D. and Zinsstag, J., 2011. Prevalence of bovine tuberculosis in pastoral cattle herds in the Oromia region, southern Ethiopia, Tropical Animal Health and Production, 43, 1081-1087PubMedCrossRefGoogle Scholar
  16. Homewood, K. 2008. Ecology of African pastoralist societies, Ohio University Press Athens, OH, USAGoogle Scholar
  17. Jiwa, S.F.H., Kazwala, R.R., Tungaraza, R., Kimera, S.I. and Kalaye, W.J., 1996. Bovine brucellosis serum agglutination test prevalence and breed disposition according to prevalent management systems in the Lake Victoria zone of Tanzania, Preventive Veterinary Medicine, 26, 341-346CrossRefGoogle Scholar
  18. Jori, F., Mokospasetso, M., Etter, E., Munstermann, S., Newman, S.H. and Michel, A., 2013. Preliminary assessment of bovine tuberculosis at the livestock/wildlife interface in two protected areas of northern Botswana, Transboundary and Emerging Diseases, 60, 28-36. doi:10.1111/tbed.12110.PubMedCrossRefGoogle Scholar
  19. Katale, B.Z., Mbugi, E.V., Karimuribo, E.D., Keyyu, J.D., Kendall, S., Kibiki, G.S., Godfrey-Faussett, P., Michel, A.L., Kazwala, R.R., van Helden, P. and Matee, M.I., 2013. Prevalence and risk factors for infection of bovine tuberculosis in indigenous cattle in the Serengeti ecosystem, Tanzania, BMC Veterinary Research, 9, doi:10.1186/1746-6148-9-267 Google Scholar
  20. Kulldorf, M., 1997. A spatial scan statistic, Communications in Statistics - Theory and Methods, 26, 1481 – 1496CrossRefGoogle Scholar
  21. Matope, G., Bhebhe, E., Muma, J.B., Lund, A. and Skjerve, E., 2010. Herd-level factors for Brucella seropositivity in cattle reared in smallholder dairy farms of Zimbabwe, Preventive Veterinary Medicine, 94, 213-221PubMedCrossRefGoogle Scholar
  22. Mazet, J.A., Clifford, D.L., Coppolillo, P.B., Deolalikar, A.B..., Erickson, J.D. and Kazwala, R.R., 2009. A "one health" approach to address emerging zoonoses: the HALI project in Tanzania, PLoS Medicine 6, e1000190. doi:10.1371/journal.pmed.1000190 PubMedCentralPubMedCrossRefGoogle Scholar
  23. McDermott, J.J. and Arimi, S.M., 2002. Brucellosis in sub-Saharan Africa: epidemiology, control and impact, Veterinary Microbiology, 90, 111-134PubMedCrossRefGoogle Scholar
  24. Mfinanga, S.G., Morkve, O., Kazwala, R.R., Cleaveland, S., Sharp, J.M., Shirima, G. and Nilsen, R., 2003. The role of livestock keeping in tuberculosis trends in Arusha, Tanzania, International Journal of Tuberculosis and Lung Disease, 7, 695-704Google Scholar
  25. Motsi, T.R., Tichiwangana, S.C., Matope, G. and Mukarati, N.L., 2013. A serological survey of brucellosis in wild ungulate species from five game parks in Zimbabwe, Onderstepoort Journal of Veterinary Research, 80, doi:10.4102/ojvr.v80i1.586.
  26. Muma, J., Samui, K., Siamudaala, V., Oloya, J., Matope, G., Omer, M., Munyeme, M., Mubita, C. and Skjerve, E., 2006. Prevalence of antibodies to Brucella spp. and individual risk factors of infection in traditional cattle, goats and sheep reared in livestock–wildlife interface areas of Zambia, Tropical Animal Health and Production, 38, 195-206PubMedCrossRefGoogle Scholar
  27. Munyeme, M., Muma, J., Samui, K., Skjerve, E., Nambota, A., Phiri, I., Rigouts, L. and Tryland, M., 2009. Prevalence of bovine tuberculosis and animal level risk factors for indigenous cattle under different grazing strategies in the livestock/wildlife interface areas of Zambia, Tropical Animal Health and Production, 41, 345-352PubMedCrossRefGoogle Scholar
  28. Munyeme, M. and Munang'andu, H.M., 2011. A review of bovine tuberculosis in the Kafue basin ecosystem, Veterinary Medicine International 2011, 918743. doi:10.4061/2011/918743 PubMedCentralPubMedCrossRefGoogle Scholar
  29. Mwakalila, S., 2011: Assessing the hydrological conditions of the Usangu Wetlands in Tanzania, Journal of Water Resource and Protection, 3, 876-882CrossRefGoogle Scholar
  30. Mwakapuja, R.S., Makondo, Z.E., Malakalinga, J., Bryssinckx, W., Mdegela, R.H., Moser, I., Kazwala, R.R. and Tanner, M., 2013. Prevalence and significant geospatial clusters of bovine tuberculosis infection at livestock-wildlife interface ecosystem in Eastern Tanzania, Tropical Animal Health and Production, 45, 1223-30PubMedCrossRefGoogle Scholar
  31. Oloya, J., Muma, J.B., Opuda-Asibo, J., Djønne, B., Kazwala, R. and Skjerve, E. 2007. Risk factors for herd-level bovine-tuberculosis seropositivity in transhumant cattle in Uganda, Preventive Veterinary Medicine, 80, 318-329PubMedCrossRefGoogle Scholar
  32. Swai, E.S. and Schoonman, L., 2010. The use of rose bengal plate test to asses cattle exposure to Brucella infection in traditional and smallholder dairy production systems of Tanga region of Tanzania, Veterinary Medicine International 2010. doi:10.4061/2010/837950
  33. Swai, E.S. and Schoonman, L., 2012. Differences in prevalence of tuberculosis in indigenous and crossbred cattle under extensive and intensive management systems in Tanga region of Tanzania, Tropical Animal Health and Production, 44, 459-465PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  • Annette Roug
    • 1
  • Deana Clifford
    • 1
  • Jonna Mazet
    • 1
  • Rudovick Kazwala
    • 2
  • Julius John
    • 2
  • Peter Coppolillo
    • 3
    • 4
  • Woutrina Smith
    • 1
  1. 1.Wildlife Health Center One Health Institute, School of Veterinary MedicineUniversity of California, DavisDavisUSA
  2. 2.Department of Veterinary Medicine and Public HealthSokoine University of AgricultureMorogoroTanzania
  3. 3.Ruaha Landscape ProgrammeWildlife Conservation SocietyIringaTanzania
  4. 4.Working Dogs for ConservationThree ForksUSA

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