Tropical Animal Health and Production

, Volume 45, Issue 6, pp 1277–1279 | Cite as

Seroprevalence of bovine tuberculosis infection in yaks (Bos grunniens) on the Qinghai-Tibetan Plateau of China

  • Zhaoqing Han
  • Jianfeng Gao
  • Muhammad Shahzad
  • Xianrong Meng
  • Mengyuan Liu
  • Kerong Zhang
  • Ding Zhang
  • Aizhen Guo
  • Suolang Sizhu
  • Jiakui Li
Regular Articles

Abstract

Bovine tuberculosis (BTB), a chronic disease caused by Mycobacterium bovis, has been widely reported in bovines in developing countries, but there is little information on this infection in domestic yaks. Seroprevalence of antibodies to M. bovis in yaks from six and three regions of Tibet and Qinghai plateau, China, respectively, was investigated in 2011 by enzyme-linked immunosorbent assay kits. A total of 1,244 (Tibet 938, Qinghai 306) blood samples was collected and the results showed that 24 (2.6 %) of Tibetan samples and 3 (1 %) of Qinghai's samples were positive for BTB. The findings of the present study indicated that M. bovis infection is prevalent in Chinese yaks in Qinghai and Tibet. These observations should raise a serious public health concern considering the extent to which the herdsmen of the study areas are in contact with their animals and the levels at which they use untreated livestock products. This is the first study showing the infection of M. bovis in domestic yaks.

Keywords

Yaks Bovine tuberculosis ELISA The Qinghai–Tibet Plateau of China 

Notes

Acknowledgments

This study was supported by the Tibet Autonomous Region Science Fund and the Chinese Agricultural Research Systems (CARS-38).

References

  1. Awah-Ndukum, J., Kudi, A.C., Bah, G.S., Bradley, G., Tebug, S.F., Dickmu, P.L., Njakoi, H.N., Agharih, W.N., 2012. Bovine tuberculosis in cattle in the highlands of Cameroon: seroprevalence estimates and rates of tuberculin skin test reactors at modified cut-offs. Veterinary Medicine International, doi: 10.1155/2012/798502
  2. Ayele, W.Y., Neill, S.D., Zinsstag, J., Weiss, M.G., Pavlik, I., 2004. Bovine tuberculosis: an old disease but a new threat to Africa. The International Journal of Tuberculosis and Lung Disease: The Official Journal of the International Union Against Tuberculosis and Lung Disease 8(8), 924–37Google Scholar
  3. Biet, F., Boschiroli, M.L., Thorel, M.F., Guilloteau, L.A., 2005. Zoonotic aspects of Mycobacterium bovis and Mycobacterium avium-intracellulare complex (MAC). Veterinary Research 36 (3), 411–36PubMedCrossRefGoogle Scholar
  4. Boadella, M., Lyashchenko, K., Greenwald, R., Esfandiari, J., Jaroso, R., Carta, T., Garrido, J.M., Vicente, J., de, la, Fuente, J., Gortázar, C., 2011. Serologic tests for detecting antibodies against Mycobacterium bovis and Mycobacterium avium subspecies. J Vet Diagn Invest. 23(1):77–83Google Scholar
  5. Cleaveland, S., Shaw, D.J., Mfinanga, S.G., Shirima, G., Kazwala, R.R., Eblate, E., Sharp, M., 2007. Mycobacterium bovis in rural Tanzania: Risk factors for infection in human and cattle populations, Tuberculosis, 87: 30–43PubMedCrossRefGoogle Scholar
  6. Cosivi, O., Grange, J.M., Daborn, C.J., Raviglione, M.C., Fujikura, T., Cousins, D., Robinson, R.A., Huchzermeyer, H.F., de, Kantor, I., Meslin, F.X., 1998. Zoonotic tuberculosis due to Mycobacterium bovis in developing countries, Emerging Infectious Diseases, 4, 59–70PubMedCrossRefGoogle Scholar
  7. Gao, J.F., Liu, M.Y., Meng, X.R., Han, Z.Q., Zhang, D., Hou, B., Zhang, K.R., Sizhu, S.L., Li, J.K., 2012. Seroprevalence of bovine viral diarrhea infection in Yaks (Bos grunniens) on the Qinghai-Tibetan Plateau of China. Tropical Animal Health and Production doi: 10.1007/s11250-012-0290-2
  8. Gumi, B., Schelling, E., Firdessa, R., Erenso, G., Biffa, D., Aseffa, A., Tschopp, R., Yamuah, L., Young, D., Zinsstag, J., 2012. Low prevalence of bovine tuberculosis in Somali pastoral livestock, southeast Ethiopia. Tropical Animal Health and Production 44(7), 1445–50PubMedCrossRefGoogle Scholar
  9. Khan, I.A., Khan, A., Mubarak, A., Ali, A., 2008. Factors affecting prevalence of bovine tuberculosis in Nili Ravi buffaloes, Pakistan Veterinary Journal, 28(4): 155–158Google Scholar
  10. Lamichhaney, S., (2010) Prevalence and Risk Factor Assessment of Bovine Tuberculosis: Impact of the disease in wildlife, domestic animals and human interface at Koshi Tappu Wildlife Reserve in Eastern Nepal. Lambert Academic Publishing, Saarbrücken, GermanyGoogle Scholar
  11. Lang X.L., Qu, H.L., Bu, Z.Y., Yang, Y.L., Sun, C.H., Li, X.Y., Wang, J.L., Cai, J.S., Ma, R.L., Fu, Y.J., Wang, X.L., 2011. Seroprevalence of Brucella infection in yaks (Bos grunniens) on the Qinghai-Tibet plateau of China, Tropical Animal Health and Production, 43: 305–306CrossRefGoogle Scholar
  12. Liu, J., Cai, J.Z., Zhang, W., Liu, Q., Chen, D., Han, J.P., Liu, Q.R., 2008. Seroepidemiology of Neospora caninum and Toxoplasma gondii infection in yaks (Bos grunniens) in Qinghai, China, Veterinary Parasitology, 152, 330–332PubMedCrossRefGoogle Scholar
  13. OIE, 2009. Office International des Epizooties Terrestrial manual: Chapter 2.4.7, World Health Organization for Animal Health, ParisGoogle Scholar
  14. Schiller, I., Vordermeier, H.M., Waters, W.R., Whelan, A.O., Coad, M., Gormley, E., Buddle, B.M., Palmer, M., Thacker, T., McNair, J., Welsh, M., Hewinson, R.G., Oesch, B., 2010. Bovine tuberculosis: Effect of the tuberculin skin test on in vitro interferon gamma responses. Veterinary Immunology and Immunopathology 136(1–2), 1–11PubMedCrossRefGoogle Scholar
  15. Tschopp, R., Aseffa, A., Schelling, E., Berg, S., Hailu, E., Gadisa, E., Habtamu, M., Argaw, K., Zinsstag, J., 2010. Bovine tuberculosis at the wildlife-livestock-human interface in Hamer Woreda, South Omo, Southern Ethiopia. PLoS One, 17: 5–8Google Scholar
  16. Zhang, L.X., Sun, Y., Yang, L., Li, G.L., 2011. Epidemic situation of tuberculosis in Tibet, Journal of Clinical Pulmonary Medicine, 16: 1268–1269Google Scholar
  17. Zinsstag, J., Schelling, E., Roth, F. and Kazwala, R., 2006. Economics of Bovine Tuberculosis. In: Thoen, C.O., Steele, J.H., Gilsdorf, M.J. (2nd eds), Mycobacterium bovis infection in animals and humans. Blackwell, BostonGoogle Scholar

Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • Zhaoqing Han
    • 1
    • 2
  • Jianfeng Gao
    • 1
  • Muhammad Shahzad
    • 1
  • Xianrong Meng
    • 1
  • Mengyuan Liu
    • 1
  • Kerong Zhang
    • 1
  • Ding Zhang
    • 1
  • Aizhen Guo
    • 1
  • Suolang Sizhu
    • 2
  • Jiakui Li
    • 1
    • 2
  1. 1.College of Veterinary MedicineHuazhong Agricultural UniversityWuhanPeople’s Republic of China
  2. 2.Laboratory of Detection and Monitoring of Highland Animal DiseasesTibet Agricultural and Animal Husbandry CollegeLinzhiPeople’s Republic of China

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