Brucellosis seroprevalence in livestock in Uganda from 1998 to 2008: a retrospective study
A total of 17,359 samples were analysed serologically, of which 1,061, 15,758 and 585 samples were from Makerere, Entebbe and Tororo laboratories, respectively, were used to determine the seroprevalence of brucellosis. The overall seroprevalence of brucellosis was 10% while from individual laboratories was 38%, 32% and 7% for Makerere, Entebbe and Tororo laboratories, respectively. Majority of these positive brucellosis test results were in the cattle corridor with P value = 0.399. There were significant differences in brucellosis seroprevalence among species (P value = 0.014). The trends of brucellosis seroprevalence among the different species were decreasing with time but were highest in bovine species (P value = 0.043). Brucellosis seroprevalence had a bimodal monthly pattern corresponding with rainfall. The study showed that brucellosis was prevalent, though the trend of the disease has declined over years. It was recommended that regular disease surveillance, control programmes and further studies be carried out in the country.
KeywordsBrucellosis Seroprevalence Host species Retrospective
The authors wish to appreciate the University of Edinburgh, Commonwealth and the diagnostic laboratories for financial, academic and material support towards the completion of this research.
- CABI, 2007. Animal Health and Production Compendium. CABI, Wallingford.Google Scholar
- Elliott, G., 2008. District Creation and Decentralisation in Uganda. Crisis States Research Centre, Development studies Institute, London School of Economics and Political Science, London, 2008-01Google Scholar
- FAO, 1993. Food and Agriculture Organisation. Chapter 5: livestock husbandry and production. The Borana Plateau of Southern Ethiopia: synthesis of pastoral research, development and change, 1980–91. International Livestock Centre for Africa (ILCA) Addis Ababa, EthiopiaGoogle Scholar
- FAO, 2009. Food and Agriculture Organisation: The State of Food and Agriculture. ISSN 0081-4539. Rome.Google Scholar
- Faye, B., Castel, V., Lesnoff, M., Rutabinda, D., and Dhalwa, J., 2005. Tuberculosis and brucellosis seroprevalence survey on dairy cattle in Mbarara milk basin (Uganda). Preventive Veterinary Medicine 67(2005) 267–281. Elsevier.Google Scholar
- Gul, S.T., and Khan, A., 2007. Epidemiology and epizootology of brucellosis: a review of Pakistan Veterinary Journal, 2007, 27(3) 145–151Google Scholar
- Kabagambe, E.K., Elzer, P.H., Geaghan, J.P., Opuda-Asibo, J., Scholl, D.T., and Miller, J.E., 2001. Risk factors for Brucella seropositivity in goats herds in eastern and western Uganda. Preventive Veterinary Medicine 52(2001) 91–108. Elsevier Science.Google Scholar
- Kalema-Zikusoka, G., Bengis, R.G., Michel, A.L., and Woodford, M.H., 2005. A preliminary investigation of tuberculosis and other diseases in African buffalo (Syncerus caffer) in Queen Elizabeth National park, Uganda. Onderstepoort Journal of Veterinary Resources. 2005 June; 72 (2): 145–51.Google Scholar
- Magona, J.W., Walubengo, J., Galiwango, T., and Etoori, T., 2009. Sero seroprevalence and potential risk of bovine brucellosis in zero grazing and pastoral dairy systems in Uganda. Tropical Animal Health Production (2009) 41:1765–1771. doi: 10.1007/s11250-009-9375-y, Springer Science + Business Media B.V. 2009
- Makita, K. E., Fèvre, M., Waiswa, C., Kaboyo, W., De Clare Bronsvoort, B. M., Eisler, M. C., and Welburn, S.C., 2008. Human brucellosis in urban and peri-urban areas of Kampala, Uganda. Animal Biodiversity and Emerging Diseases: Annals of New York. Academy of Science. 1149: 309–311 (2008). doi: 10.1196/annals.1428.015. 2008. New York Academy of Sciences.
- Mangen, M.J., Otte, J., Pfeiffer, D., and Chilonda, P., 2002. Bovine brucellosis in Sub-Saharan Africa: estimation of sero-seroprevalence and impact on meat and milk off take potential. FAO, 2002.Google Scholar
- Maurin, M., 2008. Brucellosis at the dawn of the 21st century. Medical Malignant Infections. 2005 January :35 (1):6–16.Google Scholar
- Merck’s, 2008. The Merck’s Veterinary Manual. Merck & Co., Inc. Whitehouse Station, NJ, USA. Merial Ltd.Google Scholar
- Nakavuma, J., Kibirige-Ssebunya, I., and Opuda-Asibo, J., 1999. Serosurvey of Brucella abortus in cattle and goats in Central and Southern Uganda. Uganda Journal of Agricultural Sciences, 4:13–18.Google Scholar
- OIE, 2009. OIE Terrestrial Manual 2009. Chapter 2.4.3. Bovine brucellosis. Pages 1–35.Google Scholar
- Oloffs, A., Baumann, M.P.O., Afema, J, and Nakavuma, J., 1998. Experiences with a strategy to investigate bovine brucellosis in a rural area in Southwest Uganda. Revue Elev. Med. Vet. Pays trop., 1998 51 (2)101–105.Google Scholar
- Sheik, A.A., 2005. A cross boarder research on management practices that influence seroprevalence of brucellosis in cattle and goats in Busia district of Kenya and Uganda. Dissertation for a ward of Bachelor of veterinary Medicine degree of Makerere University, Kampala Uganda. Unpublished report.Google Scholar
- Ssedyabane-Nsubuga, 2005. Brucellosis seroprevalence in pigs from two abattoirs around Kampala, Uganda. Special Project Report for award of Bachelors degree of Biomedical and Laboratory Technology. Makerere University Kampala. Unpublished report.Google Scholar
- Weinhaupl, I., Schopf, K.C., Khaschabi, D., Kapaga, A.M., and Msami, H.M., 2000. Investigations on the seroprevalence of bovine Tuberculosis and brucellosis in dairy cattle in Dar es Salaam region and Zebu cattle in Lugoba area, Tanzania. Tropical Animal Health and Production, 32(2000) 147–154. Kluwer, Netherlands.Google Scholar